Neurology Clinical Trials

Statistical methods in neurology trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All neurology trials

1,213 results

• SDFCIndependent statistical analysis of Olfactory Contributions to Sleep-dependent Food Craving: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04179838).Phase NAResults postedn = 29NCT04179838
• SDTTIndependent statistical analysis of Assessment of Laryngopharyngeal Sensation in Adductor Spasmodic Dysphonia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05158179).Phase NAResults postedn = 13NCT05158179
• SERENITY IIIndependent statistical analysis of Dexmedetomidine in the Treatment of Agitation Associated With Bipolar Disorder: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04276883).Phase 3Results postedn = 380NCT04276883
• SKYGGNIndependent statistical analysis of OCS-01 in Treating Inflammation and Pain in Post-cataract Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04130802).Phase 2Results postedn = 153NCT04130802
• SLD3Independent statistical analysis of Assessment of Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia and Frontotemporal Dementia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 1Results postedn = 81NCT02736695
• SLUMBERIndependent statistical analysis of Improving Sleep Using Mentored Behavioral and Environmental Restructuring: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03327324).Phase NAResults postedn = 110NCT03327324
• SOCRATESIndependent statistical analysis of the SOCRATES phase 3 trial of ticagrelor versus acetylsalicylic acid after acute ischaemic stroke or transient ischaemic attack, including endpoint definitions, Cox and logistic regression methods, efficacy results,…Phase 3Results postedn = 13,307NCT01994720
• SOMNOSIndependent statistical analysis of Effects of Continuous Positive Airway Pressure (CPAP) on Glucose Metabolism: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01503164).Phase NAResults postedn = 111NCT01503164
• SPACEIndependent statistical analysis of SPACE (NCT00514644), a diagnostic study evaluating carotid ultrasound and Panorama examination in patients with carotid stenoses. Includes the registered endpoint, trial design, planned prevalence analysis, and statistical interpretation.Phase NAn = 266NCT00514644
• SPAFIndependent statistical analysis of Apixaban Drug Utilization Study In Stroke Prevention In Atrial Fibrillation (Spaf): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 51,690NCT03441633
• SPARKIndependent statistical analysis of Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Participants With Parkinson's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 2Results postedn = 357NCT03318523
• SPARKIndependent statistical analysis of Kuvan® in Phenylketonuria Patients Less Than 4 Years Old: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01376908).Phase 3Results postedn = 56NCT01376908
• SPARK2Independent statistical analysis of Phase 2B Study Assessing Pain Relief After Replacement of the Knee: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 2Results postedn = 226NCT06799845
• SPIRE-1An independent statistical analysis of SPIRE-1 (NCT01975376), the terminated phase 3 placebo-controlled trial of bococizumab for prevention of major cardiovascular events: stratified Cox hazard ratios, MMRM and ANCOVA lipid analyses, multiplicity and…Phase 3Results postedn = 16,784NCT01975376
• SPIRE-2Independent statistical analysis of SPIRE-2 (NCT01975389), the terminated phase 3 placebo-controlled trial of bococizumab in high-risk participants: stratified Cox hazard ratios for major cardiovascular events, MMRM and ANCOVA lipid analyses, and serious…Phase 3Results postedn = 10,564NCT01975389
• SPS3A detailed statistical review of SPS3, a randomized phase 3 trial of secondary prevention of small subcortical strokes, including its trial design, registered endpoints, planned statistical analysis, and interpretation.Phase 3n = 3,020NCT00059306
• SPTIndependent statistical analysis of Brain Biomarkers of Response to Treatment for Apraxia of Speech: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02046941).Phase NAResults postedn = 17NCT02046941
• STARSIndependent statistical analysis of A Randomized Placebo-Controlled Study of Lovastatin in Children With Neurofibromatosis Type 1: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 146NCT00853580
• STEADFASTIndependent statistical analysis of Long-Term Safety Extension Study of ACTIMMUNE® (Interferon γ-1b) in Children and Young Adults With Friedreich's Ataxia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 38NCT02797080
• STEP-BDAn independent statistical analysis and educational interpretation of STEP-BD, a randomized, double-blind treatment study in bipolar disorder with an enrollment of 5,000 participants.Phase NAn = 5,000NCT00012558
• STEP-HomeIndependent statistical analysis of Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03868930).Phase NAResults postedn = 221NCT03868930
• STOMPIndependent statistical analysis of Evaluation of an Interactive Opioid Risk Education Program (STOMP) for Parents: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 712NCT03287622
• STOP-TICIndependent statistical analysis of Combined CBIT and rTMS to Improve Tourette's Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04795908).Phase NAResults postedn = 3NCT04795908
• STRIVEComplete statistical analysis of the STRIVE phase 3 trial of erenumab for migraine prevention, including randomized trial design, primary and secondary endpoint analyses, mixed-effects models, Cochran-Mantel-Haenszel testing, multiplicity, and safety.Phase 3Results postedn = 955NCT02456740
• SUMMITIndependent statistical analysis of A Randomized, Double-Blind, Parallel Group, Placebo-Controlled Study to Assess STS101 in the Acute Treatment of Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 1,591NCT04940390
• SUMMIT-LTSIndependent statistical analysis of Long-Term Safety and Tolerability Study of NKTR-181 in Subjects With Chronic Low Back Pain or Chronic Non-Cancer Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 3Results postedn = 638NCT02367820
• SURMOUNT-OSAIndependent statistical analysis of SURMOUNT-OSA, a randomized phase 3 trial of tirzepatide in participants with obstructive sleep apnea and obesity, including AHI results, ANCOVA, logistic regression, confidence intervals, and safety.Phase 3Results postedn = 469NCT05412004
• SWIFT DIRECTIndependent statistical analysis of SWIFT DIRECT (NCT03192332), a randomized trial comparing bridging thrombolysis with direct mechanical thrombectomy in acute ischemic stroke, including its design, modified Rankin Scale endpoint, planned analysis, and statistical…Phase NAn = 410NCT03192332
• Symptoms-StepsIndependent statistical analysis of In Person and mHealth Coping Skills Training for Symptom Management and Steps in Stem Cell Transplant Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase NAResults postedn = 40NCT03859765
• T-jet®Independent statistical analysis of Comparison of a Needle-free Injection Method With a Needle-syringe Injection Method: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 4Results postedn = 52NCT00990340
• TANGOIndependent statistical analysis of A Phase 3 Study of Tanezumab for Chronic Low Back Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 3Results postedn = 1,832NCT02528253
• TARDISIndependent statistical analysis of the TARDIS phase 3 trial evaluating triple antiplatelet therapy after ischaemic stroke, including design, endpoints, planned analysis, methodology, and interpretation.Phase 3n = 3,096NCT01661322
• TEAM2Independent statistical analysis of Reducing Stroke Risk in African-American Men: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04402125).Phase NAResults postedn = 171NCT04402125
• TEMPO-2Complete statistical analysis of TEMPO-2, a randomized phase 3 trial of tenecteplase versus antiplatelet treatment for minor acute ischemic stroke with proven occlusion, including trial design, the 90-day modified Rankin Scale endpoint,…Phase 3Results postedn = 1,274NCT02398656
• TENSIONAn independent statistical analysis of TENSION (NCT03094715), a randomized trial of thrombectomy plus best medical care versus best medical care in acute stroke with extended lesion and extended time window.Phase NAn = 253NCT03094715
• TERIKIDSIndependent statistical analysis of Efficacy, Safety and Pharmacokinetics of Teriflunomide in Pediatric Patients With Relapsing Forms of Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 3Results postedn = 166NCT02201108
• TESIndependent statistical analysis of Electric Stimulation of the Eye to Improve Vision After Trauma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02019927).Phase NAResults postedn = 97NCT02019927
• THALESComplete statistical analysis of the phase 3 THALES trial of ticagrelor versus placebo in acute ischaemic stroke and transient ischaemic attack, including trial design, endpoints, Cox and logistic regression methods, efficacy results,…Phase 3Results postedn = 11,016NCT03354429
• THRACEIndependent statistical analysis of THRACE (NCT01062698), a randomized trial evaluating intra-arterial thrombectomy in acute ischemic stroke, including design, endpoints, methodology, and statistical interpretation.Phase NAn = 412NCT01062698
• THRIVEIndependent statistical analysis of Observational Study That Will Collect Information on Patients With Urea Cycle Disorders (UCDs): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 203NCT01948427
• TIRCON-EXTIndependent statistical analysis of Long-term Deferiprone Treatment in Patients With Pantothenate Kinase-Associated Neurodegeneration: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02174848).Phase 3Results postedn = 68NCT02174848
• TitAINIndependent statistical analysis of A Placebo-controlled Phase 2 Trial to Investigate the Safety and Efficacy of Secukinumab in Giant Cell Arteritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 52NCT03765788
• TMH PilotIndependent statistical analysis of Family Telemental Health Intervention for Veterans With Dementia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03116464).Phase NAResults postedn = 4NCT03116464
• TNTIndependent statistical analysis of the TNT trial (NCT00327691), a randomized phase 4 study evaluating atorvastatin for cardiovascular risk reduction through intensive LDL lowering.Phase 4n = 8,600NCT00327691
• TPMIIndependent statistical analysis of Improving Prospective Memory Via Telehealth: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05129293).Phase NAResults postedn = 35NCT05129293
• Treat & TrainIndependent statistical analysis of A Post-Marketing-Observational Study (PMOS) to Determine the Effectiveness of Combined Adalimumab Treatment and Active Supervised Training in Patients With Axial Spondyloarthritis (axSpA): primary endpoint results, effect estimate with…Phase NAResults postedn = 17NCT03258814
• TRIUMPH-2Independent statistical analysis of TRIUMPH-2, a randomized, double-blind phase 3 study of retatrutide in participants with type 2 diabetes mellitus who have obesity or overweight.Phase 3n = 1,152NCT05929079
• TSMIndependent statistical analysis of Drug and Non-Drug Treatment Of Severe Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00910689).Phase 4Results postedn = 232NCT00910689
• TWPSIndependent statistical analysis of Long-Term Effects of Torso-Weighting: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02743312).Phase NAResults postedn = 5NCT02743312
• Tx-TreatmentIndependent statistical analysis of Phase 1-2 of Temozolomide and Hypofractionated Radiotherapy in Tx of Supratentorial Glioblastoma Multiform: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 1/2Results postedn = 30NCT01120639

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