Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
1,213 results
- Tysabri JapanIndependent statistical analysis of Natalizumab (BG00002, Tysabri) Study in Japanese Participants With Relapsing-Remitting Multiple Sclerosis (RRMS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Unite-CNMIndependent statistical analysis of Early Phase Human Drug Trial to Investigate Dynamin 101 (DYN101) in Patients ≥ 16 Years With Centronuclear Myopathies: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- VIEW 2Complete statistical analysis of VIEW 2, the randomized phase 3 trial comparing aflibercept with ranibizumab in wet age-related macular degeneration, including non-inferiority methodology, ANCOVA, risk differences, and reported week 52 results.
- VISSITIndependent statistical analysis and educational interpretation of VISSIT (NCT00816166), a randomized phase 2/3 trial of the Pharos Vitesse Neurovascular Stent System plus medical therapy versus medical therapy for ischemic stroke and transient…
- VNeSTIndependent statistical analysis of Effect of Verb Network Strengthening Treatment (VNeST) on Lexical Retrieval in Aphasia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- VRIndependent statistical analysis of Immersive Virtual Reality in Stroke Pilot Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04429945).
- WAKE-UPIndependent statistical analysis of the WAKE-UP phase 3 trial evaluating MRI-based thrombolysis with alteplase in wake-up stroke, including design, endpoints, planned statistical methods, and interpretation.
- WARCEFComplete statistical analysis of the WARCEF trial, comparing warfarin with aspirin in patients with reduced cardiac ejection fraction, including trial design, time-to-event endpoints, Cox and Poisson regression, reported results, safety, and statistical…
- WASIDIndependent statistical analysis of WASID, a randomized, double-blind phase 3 trial comparing aspirin and warfarin for stroke prevention. The page explains the trial design, available registry information, planned statistical interpretation, and important…
- WHISPERIndependent statistical analysis of Effectiveness of the Precision Spinal Cord Stimulator System at Sub-Perception Amplitude: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- X-TOLEIndependent statistical analysis of A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- YOGAMAT-IIIndependent statistical analysis of Optimization and Multi-Site Feasibility of Yoga for Chronic Pain in People in YOGAMAT-II - Phase II: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- YOGAMAT-IIIndependent statistical analysis of Optimization and Multi-Site Feasibility of Yoga for Chronic Pain in People in YOGAMAT-II - Phase I: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…