Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
816 results
- ADORE BRAINIndependent statistical analysis of Brain Health in Midlife: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06640842).
- Adrenocorticotropic Hormone Stimulation in Postural Orthostatic Tachycardia Syndrome (POTS): Complete Statistical AnalysisIndependent statistical analysis of Adrenocorticotropic Hormone Stimulation in Postural Orthostatic Tachycardia Syndrome (POTS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01764711).
- ADVANCEIndependent statistical analysis of the ADVANCE phase 3 trial of blood pressure and glucose lowering for prevention of vascular disease in high-risk patients with type 2 diabetes, including its factorial design, composite…
- ADVANCEIndependent statistical analysis of the phase 3 ADVANCE trial of peginterferon beta-1a versus placebo in relapsing multiple sclerosis, covering negative binomial rate ratios for annualized relapse rate, Cox hazard ratios, lesion mean…
- AEROBICIndependent statistical analysis of Acute Exercise and the Cerebral Metabolic Response in Aging and Alzheimer's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Aging and Estrogen on Cortical Function: Complete Statistical AnalysisIndependent statistical analysis of Aging and Estrogen on Cortical Function: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01268046).
- ALDERIndependent statistical analysis of Anxiety Lowering and Deprescribing Through Emotion Regulation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06359314).
- ALFSG-MBTIndependent statistical analysis of 13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- ALIASIndependent statistical analysis of ALIAS, a randomized phase 3 trial of albumin versus saline in acute ischemic stroke, including trial design, endpoints, logistic regression, risk ratios, nonparametric analysis, safety, and interpretation.
- ALIGN: Aligning Medications With What Matters Most (Demonstration): Complete Statistical AnalysisIndependent statistical analysis of ALIGN: Aligning Medications With What Matters Most (Demonstration): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06335953).
- ALLAY-LID-IIndependent statistical analysis of Efficacy and Safety of Amantadine Hydrochloride (HCl) ER Tablets to Treat Parkinson's Disease Patients With LID.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Altering Activation Patterns Post-stroke: Complete Statistical AnalysisIndependent statistical analysis of Altering Activation Patterns Post-stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02418949).
- AltoidaMLIndependent statistical analysis of Evaluation of a Computerized Complex Instrumental Activities of Daily Living Marker (NMI): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- AMADIndependent statistical analysis of Efficacy of Acupuncture in Macular Diseases: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02255981).
- Amara View Benchmark Study: Complete Statistical AnalysisIndependent statistical analysis of Amara View Benchmark Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06535932).
- AMARANTHComplete statistical analysis of the AMARANTH phase 2/3 trial of lanabecestat in early Alzheimer's disease, including trial design, primary and secondary endpoint results, ANCOVA and mixed-effects methodology, safety, and statistical interpretation.
- AMAZEIndependent statistical analysis of Cohort 2 (Abdominoplasty) of: A Multi-surgery Assessment of ZYNRELEF (HTX-011): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06109428).
- AMPACT1Independent statistical analysis of AM-101 in the Treatment of Post-Acute Tinnitus 1: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01934010).
- An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment: Complete Statistical AnalysisIndependent statistical analysis of An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment: primary endpoint results, effect estimate with confidence interval, sample-size…
- An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSD: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Cancer Participants With Inadequately Controlled Pain by Non-Narcotic Analgesics: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Cancer Participants With Inadequately Controlled Pain by Non-Narcotic Analgesics: primary endpoint results, effect estimate with confidence interval,…
- An Efficacy and Tolerability Study of Topiramate in Participants With Migraine: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Tolerability Study of Topiramate in Participants With Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- An Electronic Clinical Decision Support Tool to Reduce Low-value Antipsychotic Prescriptions: Complete Statistical AnalysisIndependent statistical analysis of An Electronic Clinical Decision Support Tool to Reduce Low-value Antipsychotic Prescriptions: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- An Extension Study of LAQ/5062 Exploring the Long Term Safety, Tolerability and Clinical Effect Parameters During the Disease: Complete Statistical AnalysisIndependent statistical analysis of An Extension Study of LAQ/5062 Exploring the Long Term Safety, Tolerability and Clinical Effect Parameters During the Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Efficacy and Safety of Voltaren Gel in Subjects With DOMS: Complete Statistical AnalysisIndependent statistical analysis of An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Efficacy and Safety of Voltaren Gel in Subjects With DOMS: primary endpoint results, effect estimate with confidence…
- An Observational Study of BOTOX® as Headache Prophylaxis for Chronic Migraine: Complete Statistical AnalysisIndependent statistical analysis of An Observational Study of BOTOX® as Headache Prophylaxis for Chronic Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- An Open Label Study of Levetiracetam in Japanese Pediatric Patients With Partial Seizures: Complete Statistical AnalysisIndependent statistical analysis of An Open Label Study of Levetiracetam in Japanese Pediatric Patients With Partial Seizures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- An Open-label Extension Study to Evaluate the Safety and Tolerability of Perampanel (E2007) Administered as an Adjunctive Therapy in Epilepsy Subjects: Complete Statistical AnalysisIndependent statistical analysis of An Open-label Extension Study to Evaluate the Safety and Tolerability of Perampanel (E2007) Administered as an Adjunctive Therapy in Epilepsy Subjects: primary endpoint results, effect estimate with confidence…
- An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain: Complete Statistical AnalysisIndependent statistical analysis of An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD): Complete Statistical AnalysisIndependent statistical analysis of An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD): primary endpoint results, effect estimate with…
- An Open-label Study in Healthy Male Subjects to Assess the Absorption, Distribution, Metabolism and Excretion of [14C]-Labelled BIA 9-1067 and Metabolites: Complete Statistical AnalysisIndependent statistical analysis of An Open-label Study in Healthy Male Subjects to Assess the Absorption, Distribution, Metabolism and Excretion of [14C]-Labelled BIA 9-1067 and Metabolites: primary endpoint results, effect estimate with confidence…
- An Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Edge): Complete Statistical AnalysisIndependent statistical analysis of An Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Edge): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease: Complete Statistical AnalysisIndependent statistical analysis of Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00069329).
- Analysis of Electrocorticographic Signals: Complete Statistical AnalysisIndependent statistical analysis of Analysis of Electrocorticographic Signals: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03785028).
- Analysis of Snore Sound Following Minimal Invasive Surgery in Sleep-disordered Breathing Patients: Complete Statistical AnalysisIndependent statistical analysis of Analysis of Snore Sound Following Minimal Invasive Surgery in Sleep-disordered Breathing Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Anesthesia and Postoperative Pain: Complete Statistical AnalysisIndependent statistical analysis of Anesthesia and Postoperative Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00232817).
- ANGEL-ASPECTIndependent statistical analysis of ANGEL-ASPECT, a randomized trial of endovascular therapy versus best medical management in acute ischemic stroke patients with large infarct core.
- ANSWERIndependent statistical analysis of Adjunctive Neurovascular Support for Wide-neck Aneurysm Embolization and Reconstruction: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02312856).
- Anti-Diabetic Medications to Fight PD and LBD: Complete Statistical AnalysisIndependent statistical analysis of Anti-Diabetic Medications to Fight PD and LBD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06263673).
- Antibody Persistence and Booster Dose Response in Subjects Who Received Menactra® Three Years Earlier in Study MTA26: Complete Statistical AnalysisIndependent statistical analysis of Antibody Persistence and Booster Dose Response in Subjects Who Received Menactra® Three Years Earlier in Study MTA26: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Antineoplaston Therapy in Treating Patients With Meningioma: Complete Statistical AnalysisIndependent statistical analysis of Antineoplaston Therapy in Treating Patients With Meningioma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00003483).
- APEX 241Independent statistical analysis of Aripiprazole Open-Label, Safety and Tolerability Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00102518).
- Apixaban Versus Warfarin for the Management of Post-operative Atrial Fibrillation: Complete Statistical AnalysisIndependent statistical analysis of Apixaban Versus Warfarin for the Management of Post-operative Atrial Fibrillation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02889562).
- APMIndependent statistical analysis of APM in the Evoke SCS System to Program Patients With Chronic Pain of the Trunk and/or Limbs: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Application of Ideal Binary Masking to Disordered Speech: Complete Statistical AnalysisIndependent statistical analysis of Application of Ideal Binary Masking to Disordered Speech: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05244603).
- Approach to Sexuality From Occupational Therapy in People With Acquired Brain Injury in Subacute Stage: Complete Statistical AnalysisIndependent statistical analysis of Approach to Sexuality From Occupational Therapy in People With Acquired Brain Injury in Subacute Stage: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- ARDAIndependent statistical analysis of A Clinical Trial to Investigate the Safety and Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics and Immunogenicity of 2 Dose Regimens of ARGX-117 in Adults With Multifocal Motor Neuropathy: primary endpoint…
- ARESTIndependent statistical analysis of Apixaban for Early Prevention of Recurrent Embolic Stroke and Hemorrhagic Transformation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Arimoclomol in Amyotropic Lateral Sclerosis – Open Label Extension Trial: Complete Statistical AnalysisIndependent statistical analysis of Arimoclomol in Amyotropic Lateral Sclerosis - Open Label Extension Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03836716).
- Armodafinil (Nuvigil), Postoperative Recovery of OSA (Obstructive Sleep Apnea) and Obese Patients: Complete Statistical AnalysisIndependent statistical analysis of Armodafinil (Nuvigil), Postoperative Recovery of OSA (Obstructive Sleep Apnea) and Obese Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…