Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
1,025 results
- Care Partner Assisted Intervention to Improve Oral Health of Individuals With Mild Dementia: Complete Statistical AnalysisIndependent statistical analysis of Care Partner Assisted Intervention to Improve Oral Health of Individuals With Mild Dementia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- CARE-ACTIndependent statistical analysis of Caregivers' and Physicians' Treatment Preference in Parkinson Patients Treated With Neupro® Requiring Caregiver Support: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- CARESComplete statistical analysis of the CARES phase 3 trial of febuxostat versus allopurinol in participants with gout and cardiovascular comorbidities, including MACE, cardiovascular death, myocardial infarction, stroke, and survival-analysis methodology.
- Caring for Babies During the Newborn Screening Blood Test: Complete Statistical AnalysisIndependent statistical analysis of Caring for Babies During the Newborn Screening Blood Test: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02608892).
- CARTERIndependent statistical analysis of Circuitry Assessment and Reinforcement Training Effects on Recovery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04290988).
- CBTi GWIIndependent statistical analysis of Cognitive Behavioral Therapy for Insomnia for Gulf War Illness: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02782780).
- CDP-Choline and Working Memory After TBI: A Neuroimaging Study: Complete Statistical AnalysisIndependent statistical analysis of CDP-Choline and Working Memory After TBI: A Neuroimaging Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00727246).
- Cerebellar Transcranial Direct Current Stimulation and Aphasia Treatment: Complete Statistical AnalysisIndependent statistical analysis of Cerebellar Transcranial Direct Current Stimulation and Aphasia Treatment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02901574).
- CEUS For Intraoperative Spinal Cord Injury: Complete Statistical AnalysisIndependent statistical analysis of CEUS For Intraoperative Spinal Cord Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05530798).
- CGRP, Estrogen, Cortisol, VIP, α-Amylase, PGE2, PGI2 and ß-Endorphin Levels in Menstrual Migraine Before and After Treximet: Complete Statistical AnalysisIndependent statistical analysis of CGRP, Estrogen, Cortisol, VIP, α-Amylase, PGE2, PGI2 and ß-Endorphin Levels in Menstrual Migraine Before and After Treximet: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- CHALLENGEIndependent statistical analysis of Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer: primary endpoint results, effect estimate…
- Chamomile for Chronic Primary Insomnia: Complete Statistical AnalysisIndependent statistical analysis of Chamomile for Chronic Primary Insomnia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01286324).
- CHAMPSIndependent statistical analysis of Connected Health Blood Pressure Monitoring In Stroke and TIA Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02450760).
- Characteristics of Sleep Patterns in Young Adults With and Without Insomnia: Complete Statistical AnalysisIndependent statistical analysis of Characteristics of Sleep Patterns in Young Adults With and Without Insomnia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Chest Pain Perception and Capsaicin Sensitivity: Complete Statistical AnalysisIndependent statistical analysis of Chest Pain Perception and Capsaicin Sensitivity: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02346903).
- CHOOSEIndependent statistical analysis of Cross Over Convenience And Preference Study Of New Mark VII Compared To Genotropin Pen In Pediatric And Adult Subjects: primary endpoint results, effect estimate with confidence interval, sample-size…
- Chronic Liver Disease in Urea Cycle Disorders: Complete Statistical AnalysisIndependent statistical analysis of Chronic Liver Disease in Urea Cycle Disorders: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03721367).
- CHRONICLEIndependent statistical analysis of A 1-year Trial to Inform About Long-term Exposure to Eptinezumab in Participants With Chronic Cluster Headache (cCH): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Cilengitide (EMD 121974) for Recurrent Glioblastoma Multiforme (Brain Tumor): Complete Statistical AnalysisIndependent statistical analysis of Cilengitide (EMD 121974) for Recurrent Glioblastoma Multiforme (Brain Tumor): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00093964).
- CIRTIndependent statistical analysis of Cardiovascular Inflammation Reduction Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01594333).
- Citicoline in Non-Arteritic Ischemic Optic Neuropathy: Complete Statistical AnalysisIndependent statistical analysis of Citicoline in Non-Arteritic Ischemic Optic Neuropathy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03758118).
- Clarithromycin for the Treatment of Hypersomnia: Complete Statistical AnalysisIndependent statistical analysis of Clarithromycin for the Treatment of Hypersomnia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01146600).
- CLARITYIndependent statistical analysis of A Safety and Efficacy Study of Oral Cladribine in Subjects With Relapsing-remitting Multiple Sclerosis (RRMS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- CLARITY ADIndependent statistical analysis of the phase 3 CLARITY AD trial of lecanemab in participants with early Alzheimer's disease, covering trial design, CDR-SB endpoints, safety endpoints, planned statistical analysis, and interpretation.
- CLBP Single-Arm Long-Term Follow-up Study: Complete Statistical AnalysisIndependent statistical analysis of CLBP Single-Arm Long-Term Follow-up Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05207813).
- Clenbuterol on Motor Function in Individuals With Amyotrophic Lateral Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of Clenbuterol on Motor Function in Individuals With Amyotrophic Lateral Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04245709).
- Clinical Evaluation of Ropinirole Prolonged Release/Extended Release (PR/XR) Tablet for Adjunctive Therapy to L-dopa in Subjects With Advanced Parkinson’s Disease: Complete Statistical AnalysisIndependent statistical analysis of Clinical Evaluation of Ropinirole Prolonged Release/Extended Release (PR/XR) Tablet for Adjunctive Therapy to L-dopa in Subjects With Advanced Parkinson's Disease: primary endpoint results, effect estimate with confidence interval,…
- Clinical Evaluation of the Nucleus 5 Cochlear Implant (CI) System: Complete Statistical AnalysisIndependent statistical analysis of Clinical Evaluation of the Nucleus 5 Cochlear Implant (CI) System: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01072409).
- Clinical Investigation of New CI Delivery Models in an Adult Nucleus CI Population: Complete Statistical AnalysisIndependent statistical analysis of Clinical Investigation of New CI Delivery Models in an Adult Nucleus CI Population: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Clinical Management of Neuropathic Pain With Ramelteon: Complete Statistical AnalysisIndependent statistical analysis of Clinical Management of Neuropathic Pain With Ramelteon: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00753623).
- Clinical Outcomes of Deep Brain Stimulator (DBS) Electrodes Placed Using Intraoperative Computed Tomography (CT) and Frameless Stereotaxis: Complete Statistical AnalysisIndependent statistical analysis of Clinical Outcomes of Deep Brain Stimulator (DBS) Electrodes Placed Using Intraoperative Computed Tomography (CT) and Frameless Stereotaxis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Clinical Outcomes Study Using a New Implantable Neurostimulation System for Chronic Intractable Pain: Complete Statistical AnalysisIndependent statistical analysis of Clinical Outcomes Study Using a New Implantable Neurostimulation System for Chronic Intractable Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Clinical Performance of a Transcutaneous Bone Conduction Hearing Solution (Baha® Attract System): Complete Statistical AnalysisIndependent statistical analysis of Clinical Performance of a Transcutaneous Bone Conduction Hearing Solution (Baha® Attract System): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Clinical Study of Lamotrigine to Treat Newly Diagnosed Epilepsy: Complete Statistical AnalysisIndependent statistical analysis of Clinical Study of Lamotrigine to Treat Newly Diagnosed Epilepsy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01431963).
- Clinical Study on Silk Sericin Wound Dressing for Split-thickness Skin Graft Donor Sites Treatment: Complete Statistical AnalysisIndependent statistical analysis of Clinical Study on Silk Sericin Wound Dressing for Split-thickness Skin Graft Donor Sites Treatment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Clinical Trial Comparing C-Brace to Knee Ankle Foot Orthosis (KAFO)/Stance Control Orthosis (SCO): Complete Statistical AnalysisIndependent statistical analysis of Clinical Trial Comparing C-Brace to Knee Ankle Foot Orthosis (KAFO)/Stance Control Orthosis (SCO): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Clinical Trial Comparing Effectiveness of Buffered Versus Unbuffered Local Anesthetic in Children Ages 10-12 Years: Complete Statistical AnalysisIndependent statistical analysis of Clinical Trial Comparing Effectiveness of Buffered Versus Unbuffered Local Anesthetic in Children Ages 10-12 Years: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Clinical Trial of CNS-targeted HAART (CIT2): Complete Statistical AnalysisIndependent statistical analysis of Clinical Trial of CNS-targeted HAART (CIT2): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00624195).
- CLOSEA statistical analysis of the CLOSE phase 3 trial evaluating patent foramen ovale closure or anticoagulants versus antiplatelet therapy to prevent stroke recurrence.
- CLOTBUST-HFIndependent statistical analysis of CLOTBUST Hands-Free: A Phase I/II Pilot Safety Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01240356).
- CLOTS 3Independent statistical analysis of CLOTS 3 (NCT00789542), a phase 3 randomized trial evaluating intermittent pneumatic compression to prevent post-stroke deep vein thrombosis.
- Coaching for Caregivers of Children With Spinal Cord Injury: Complete Statistical AnalysisIndependent statistical analysis of Coaching for Caregivers of Children With Spinal Cord Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03898700).
- COCOVIndependent statistical analysis of Care Outcomes for Chiropractic Outpatient Veterans: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03254719).
- Cognition Platform Study in Participants at Risk for Alzheimer’s Disease (AD) (MK-0000-413): Complete Statistical AnalysisIndependent statistical analysis of Cognition Platform Study in Participants at Risk for Alzheimer's Disease (AD) (MK-0000-413): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial: Complete Statistical AnalysisIndependent statistical analysis of Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05860127).
- CogSMART-PDIndependent statistical analysis of Cognitive Rehabilitation for PD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03335150).
- Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Combined and Isolated Effects of Sleep Deprivation and Alcohol Intake on Exercise Performance in Humans.: Complete Statistical AnalysisIndependent statistical analysis of Combined and Isolated Effects of Sleep Deprivation and Alcohol Intake on Exercise Performance in Humans.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Combined Spinal/Epidural (CSE) Saline Duration/Spread: Complete Statistical AnalysisIndependent statistical analysis of Combined Spinal/Epidural (CSE) Saline Duration/Spread: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01062893).