Statistical methods in oncology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
Hazard ratio
Log-rank test
Cochran-Mantel-Haenszel test
Odds ratio
Cox proportional-hazards model
Fisher exact test
Risk difference
Stratified log-rank test
All oncology trials
2,067 results
- COG STIMIndependent statistical analysis of Management of Cognitive Difficulties After Cancer Treatments in Women Treated for Breast Cancer: Feasibility Study (Step 1 of the Cog-Stim Protocol): primary endpoint results, effect estimate with confidence…
- Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial: Complete Statistical AnalysisIndependent statistical analysis of Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05860127).
- COGNUTRIN in Breast Cancer Survivors: Complete Statistical AnalysisIndependent statistical analysis of COGNUTRIN in Breast Cancer Survivors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01823991).
- ColdPlay2Independent statistical analysis of Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Epithelium: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- COLUMBUSIndependent statistical analysis of the COLUMBUS phase 3 trial of LGX818 plus MEK162, vemurafenib, and LGX818 monotherapy in BRAF mutant melanoma, including trial design, registered PFS endpoints, planned survival analysis, and safety…
- Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine Tumors: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Combination Chemotherapy and Dasatinib in Treating Participants With Philadelphia Positive or BCR-ABL Positive Acute Lymphoblastic Leukemia.: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy and Dasatinib in Treating Participants With Philadelphia Positive or BCR-ABL Positive Acute Lymphoblastic Leukemia.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Combination Chemotherapy and Peripheral Blood Stem Cell Transplant Followed By Aldesleukin and Sargramostim in Treating Patients With Inflammatory Stage IIIB or Metastatic Stage IV Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy and Peripheral Blood Stem Cell Transplant Followed By Aldesleukin and Sargramostim in Treating Patients With Inflammatory Stage IIIB or Metastatic Stage IV Breast Cancer: primary endpoint…
- Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Burkitt’s Lymphoma or Leukemia: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Burkitt's Lymphoma or Leukemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Positive Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Positive Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Combination Chemotherapy With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck: primary endpoint results, effect estimate with…
- Combination Chemotherapy With or Without Rituximab in Treating Participants With Stage III-IV Classic Hodgkin Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy With or Without Rituximab in Treating Participants With Stage III-IV Classic Hodgkin Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Combination Chemotherapy With or Without Trastuzumab Followed By an Autologous Stem Cell Transplant and Radiation Therapy in Treating Patients With Stage III or Stage IV Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy With or Without Trastuzumab Followed By an Autologous Stem Cell Transplant and Radiation Therapy in Treating Patients With Stage III or Stage IV Breast Cancer: primary…
- Combination Chemotherapy With or Without Vismodegib in Treating Patients With Advanced Stomach Cancer or Gastroesophageal Junction Cancer: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy With or Without Vismodegib in Treating Patients With Advanced Stomach Cancer or Gastroesophageal Junction Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Combination Chemotherapy, Bev, RT, and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of Combination Chemotherapy, Bev, RT, and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Combination Immunotherapy in Biochemically Recurrent Prostate Cancer: Complete Statistical AnalysisIndependent statistical analysis of Combination Immunotherapy in Biochemically Recurrent Prostate Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03315871).
- Combination Immunotherapy With Herceptin and the HER2 Vaccine NeuVax: Complete Statistical AnalysisIndependent statistical analysis of Combination Immunotherapy With Herceptin and the HER2 Vaccine NeuVax: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01570036).
- Combination of Bevacizumab, Pertuzumab, and Sandostatin for Adv. Neuroendocrine Cancers: Complete Statistical AnalysisIndependent statistical analysis of Combination of Bevacizumab, Pertuzumab, and Sandostatin for Adv. Neuroendocrine Cancers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01121939).
- Combination of BKM120 and Bevacizumab in Refractory Solid Tumors and Relapsed/Refractory Glioblastoma Multiforme: Complete Statistical AnalysisIndependent statistical analysis of Combination of BKM120 and Bevacizumab in Refractory Solid Tumors and Relapsed/Refractory Glioblastoma Multiforme: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Combination of GTI-2040 and Cytarabine in the Treatment of Refractory and Relapsed Acute Myeloid Leukemia (AML): Complete Statistical AnalysisIndependent statistical analysis of Combination of GTI-2040 and Cytarabine in the Treatment of Refractory and Relapsed Acute Myeloid Leukemia (AML): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Combination of Taxotere and Oxaliplatin in Squamous Cell Carcinoma of the Head and Neck: Complete Statistical AnalysisIndependent statistical analysis of Combination of Taxotere and Oxaliplatin in Squamous Cell Carcinoma of the Head and Neck: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Combination Study of IPH2201 (Monalizumab) With Ibrutinib in Relapsed, Refractory or Previously Untreated CLL: Complete Statistical AnalysisIndependent statistical analysis of Combination Study of IPH2201 (Monalizumab) With Ibrutinib in Relapsed, Refractory or Previously Untreated CLL: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Combination Therapy With Imiquimod Cream 5% and Tazarotene Cream 0.1% for the Treatment of Lentigo Maligna: Complete Statistical AnalysisIndependent statistical analysis of Combination Therapy With Imiquimod Cream 5% and Tazarotene Cream 0.1% for the Treatment of Lentigo Maligna: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Combination Therapy With Nivolumab and PD-L1/IDO Peptide Vaccine to Patients With Metastatic Melanoma: Complete Statistical AnalysisIndependent statistical analysis of Combination Therapy With Nivolumab and PD-L1/IDO Peptide Vaccine to Patients With Metastatic Melanoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Combination Treatment (Talazoparib Plus Avelumab) for Stage IV or Recurrent Non-Squamous Non-Small Cell Lung Cancer With STK11 Gene Mutation (A LUNG-MAP Treatment Trial): Complete Statistical AnalysisIndependent statistical analysis of Combination Treatment (Talazoparib Plus Avelumab) for Stage IV or Recurrent Non-Squamous Non-Small Cell Lung Cancer With STK11 Gene Mutation (A LUNG-MAP Treatment Trial): primary endpoint results, effect estimate…
- Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus: Complete Statistical AnalysisIndependent statistical analysis of Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01378377).
- Combined Immunochemotherapy Followed By Reduced Dose Radiation Therapy (RT) for Patients With Newly Diagnosed Primary Central Nervous System Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Combined Immunochemotherapy Followed By Reduced Dose Radiation Therapy (RT) for Patients With Newly Diagnosed Primary Central Nervous System Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size…
- Combined Letrozole and Clomid in Women With Infertility and PCOS: Complete Statistical AnalysisIndependent statistical analysis of Combined Letrozole and Clomid in Women With Infertility and PCOS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02802865).
- Combined MRI and Optical Imaging to Improved Breast Cancer Diagnosis: Complete Statistical AnalysisIndependent statistical analysis of Combined MRI and Optical Imaging to Improved Breast Cancer Diagnosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00610467).
- Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen: Complete Statistical AnalysisIndependent statistical analysis of Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen:…
- Combined Vaginal Misoprostol and Perivascular Vasopressin: Complete Statistical AnalysisIndependent statistical analysis of Combined Vaginal Misoprostol and Perivascular Vasopressin: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03815344).
- Combo of Cabozantinib With Abiraterone in Chemotherapy-Naïve Subjects With Bone-Metastatic CRPC: Complete Statistical AnalysisIndependent statistical analysis of Combo of Cabozantinib With Abiraterone in Chemotherapy-Naïve Subjects With Bone-Metastatic CRPC: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- COMET-1Independent statistical analysis of COMET-1, the randomized phase 3 trial of cabozantinib versus prednisone in men with metastatic castration-resistant prostate cancer previously treated with docetaxel and abiraterone or MDV3100.
- COMET-2Independent statistical analysis of COMET-2, a randomized phase 3 trial comparing cabozantinib with mitoxantrone plus prednisone in men with previously treated symptomatic castration-resistant prostate cancer.
- COMETABreastIndependent statistical analysis of Analysis of Olaparib Response in Patients With BRCA1 and/or 2 Promoter Methylation Diagnosed of Advanced Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Common Safety Follow-up Trial of Tecemotide (L-BLP25): Complete Statistical AnalysisIndependent statistical analysis of Common Safety Follow-up Trial of Tecemotide (L-BLP25): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01423760).
- Community Interventions in Non-medical Settings to Increase Informed Decision Making for Prostate Cancer Screening: Complete Statistical AnalysisIndependent statistical analysis of Community Interventions in Non-medical Settings to Increase Informed Decision Making for Prostate Cancer Screening: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Comparative Analysis of Transperineal Versus Transrectal Approaches for MRI-Targeted Biopsy of the Prostate for the Detection and Characterization of Prostate Cancer: Complete Statistical AnalysisIndependent statistical analysis of Comparative Analysis of Transperineal Versus Transrectal Approaches for MRI-Targeted Biopsy of the Prostate for the Detection and Characterization of Prostate Cancer: primary endpoint results, effect estimate with confidence…
- Compare Propofol to Fentanyl and Midazolam for Colonoscopy: Complete Statistical AnalysisIndependent statistical analysis of Compare Propofol to Fentanyl and Midazolam for Colonoscopy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01488045).
- Comparing Efficacy and Safety Between Pertuzumab® and Perjeta® in Neoadjuvant Treatment of HER2+ Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of Comparing Efficacy and Safety Between Pertuzumab® and Perjeta® in Neoadjuvant Treatment of HER2+ Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Comparing Efficacy and Safety of Stivant (AryoGen Bevacizumab) Versus Avastin in Metastatic Colorectal Cancer: Complete Statistical AnalysisIndependent statistical analysis of Comparing Efficacy and Safety of Stivant (AryoGen Bevacizumab) Versus Avastin in Metastatic Colorectal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Comparing Two Forms of Head Immobilization for Stereotactic Radiotherapy: Complete Statistical AnalysisIndependent statistical analysis of Comparing Two Forms of Head Immobilization for Stereotactic Radiotherapy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00328510).
- Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery: Complete Statistical AnalysisIndependent statistical analysis of Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in…
- Comparison of a Novel 22-gauge Core Biopsy Needle: Complete Statistical AnalysisIndependent statistical analysis of Comparison of a Novel 22-gauge Core Biopsy Needle: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01598194).
- Comparison of Fluconazole vs Voriconazole to Treat Fungal Infections for Blood and Marrow Transplants (BMT CTN 0101): Complete Statistical AnalysisIndependent statistical analysis of Comparison of Fluconazole vs Voriconazole to Treat Fungal Infections for Blood and Marrow Transplants (BMT CTN 0101): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Comparison of IV Topotecan/Docetaxel to Docetaxel Alone in Second-Line Stage IIIB/IV Non-Small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of Comparison of IV Topotecan/Docetaxel to Docetaxel Alone in Second-Line Stage IIIB/IV Non-Small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…