Statistical methods in oncology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
Hazard ratio
Log-rank test
Cochran-Mantel-Haenszel test
Odds ratio
Cox proportional-hazards model
Fisher exact test
Risk difference
Stratified log-rank test
All oncology trials
1,418 results
- A Study of LY3039478 in Participants With Advanced Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY3039478 in Participants With Advanced Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01695005).
- A Study of MabThera (Rituximab) in Elderly Patients With Untreated Follicular Non-Hodgkin’s Lymphoma (NHL): Complete Statistical AnalysisIndependent statistical analysis of A Study of MabThera (Rituximab) in Elderly Patients With Untreated Follicular Non-Hodgkin's Lymphoma (NHL): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of MabThera/Rituxan (Rituximab) Alone and in Combination With Roferon-A in Patients With Follicular or Other CD20+ Low-Grade (Indolent) Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of MabThera/Rituxan (Rituximab) Alone and in Combination With Roferon-A in Patients With Follicular or Other CD20+ Low-Grade (Indolent) Lymphoma: primary endpoint results, effect estimate with confidence…
- A Study of Management of Tarceva – Induced Rash in Patients With Non-Small Cell Lung Cancer.: Complete Statistical AnalysisIndependent statistical analysis of A Study of Management of Tarceva - Induced Rash in Patients With Non-Small Cell Lung Cancer.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of Midostaurin Efficacy and Safety in Newly Diagnosed Patients With FLT3-mutated AML: Complete Statistical AnalysisIndependent statistical analysis of A Study of Midostaurin Efficacy and Safety in Newly Diagnosed Patients With FLT3-mutated AML: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of MORAb-202 Versus Investigator’s Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of MORAb-202 Versus Investigator's Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer: primary endpoint results, effect estimate…
- A Study of Nab-Paclitaxel and Gemcitabine With or Without Olaratumab (LY3012207) in Participants With Metastatic Pancreatic Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Nab-Paclitaxel and Gemcitabine With or Without Olaratumab (LY3012207) in Participants With Metastatic Pancreatic Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study of Nanrilkefusp Alfa (SOT101) in Combination With Cetuximab to Evaluate the Efficacy and Safety in Patients With Colorectal Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Nanrilkefusp Alfa (SOT101) in Combination With Cetuximab to Evaluate the Efficacy and Safety in Patients With Colorectal Cancer: primary endpoint results, effect estimate with confidence…
- A Study of Necitumumab in the First-Line Treatment of Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC): Complete Statistical AnalysisIndependent statistical analysis of A Study of Necitumumab in the First-Line Treatment of Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of NOX66 and External Beam Radiotherapy in Patients With Metastatic Castration-resistant Prostate Cancer and Other Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of A Study of NOX66 and External Beam Radiotherapy in Patients With Metastatic Castration-resistant Prostate Cancer and Other Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of Obinutuzumab + Bendamustine (BG) in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL): Complete Statistical AnalysisIndependent statistical analysis of A Study of Obinutuzumab + Bendamustine (BG) in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of Obinutuzumab in Combination With Idasanutlin and Venetoclax in Participants With Relapsed or Refractory (R/R) Follicular Lymphoma (FL) or Rituximab in Combination With Idasanutlin and Venetoclax in Participants With R/R Diffuse Large B-Cell Lymphoma (DLBCL): Complete Statistical AnalysisIndependent statistical analysis of A Study of Obinutuzumab in Combination With Idasanutlin and Venetoclax in Participants With Relapsed or Refractory (R/R) Follicular Lymphoma (FL) or Rituximab in Combination With Idasanutlin and Venetoclax…
- A Study of ONO-7475 in Patients With Acute Leukemias: Complete Statistical AnalysisIndependent statistical analysis of A Study of ONO-7475 in Patients With Acute Leukemias: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03176277).
- A Study of Oprozomib, Pomalidomide, and Dexamethasone in Adults With Primary Refractory or Relapsed and Refractory Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Oprozomib, Pomalidomide, and Dexamethasone in Adults With Primary Refractory or Relapsed and Refractory Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study of Oral Rucaparib in Patients With a Solid Tumor (Phase I) or With gBRCA Mutation Ovarian Cancer (Phase II): Complete Statistical AnalysisIndependent statistical analysis of A Study of Oral Rucaparib in Patients With a Solid Tumor (Phase I) or With gBRCA Mutation Ovarian Cancer (Phase II): primary endpoint results, effect estimate with confidence…
- A Study of Participant Preference With Subcutaneous Versus Intravenous MabThera/Rituxan in Participants With CD20+ Diffuse Large B-Cell Lymphoma or CD20+ Follicular Non-Hodgkin’s Lymphoma Grades 1, 2 or 3a: Complete Statistical AnalysisIndependent statistical analysis of A Study of Participant Preference With Subcutaneous Versus Intravenous MabThera/Rituxan in Participants With CD20+ Diffuse Large B-Cell Lymphoma or CD20+ Follicular Non-Hodgkin's Lymphoma Grades 1, 2 or 3a:…
- A Study of Patients Who Received Inotuzumab Ozogamicin for B-cell ALL (Acute Lymphoblastic Leukemia) That Occurred Again After the Last Treatment: Complete Statistical AnalysisIndependent statistical analysis of A Study of Patients Who Received Inotuzumab Ozogamicin for B-cell ALL (Acute Lymphoblastic Leukemia) That Occurred Again After the Last Treatment: primary endpoint results, effect estimate with confidence…
- A Study of PCI-32765 (Ibrutinib) Versus Rituximab in Relapsed or Refractory Chronic Leukemia/Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of PCI-32765 (Ibrutinib) Versus Rituximab in Relapsed or Refractory Chronic Leukemia/Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of Pembrolizumab (MK-3475) in Combination With Chemotherapy or Immunotherapy in Participants With Non-small Cell Lung Cancer (MK-3475-021/KEYNOTE-021): Complete Statistical AnalysisIndependent statistical analysis of A Study of Pembrolizumab (MK-3475) in Combination With Chemotherapy or Immunotherapy in Participants With Non-small Cell Lung Cancer (MK-3475-021/KEYNOTE-021): primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of Pembrolizumab (MK-3475) in Relapsed or Refractory Classical Hodgkin’s Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-B68): Complete Statistical AnalysisIndependent statistical analysis of A Study of Pembrolizumab (MK-3475) in Relapsed or Refractory Classical Hodgkin's Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-B68): primary endpoint results, effect…
- A Study of Pembrolizumab (MK-3475) Versus Paclitaxel, Docetaxel, or Vinflunine for Participants With Advanced Urothelial Cancer (MK-3475-045/KEYNOTE-045): Complete Statistical AnalysisIndependent statistical analysis of A Study of Pembrolizumab (MK-3475) Versus Paclitaxel, Docetaxel, or Vinflunine for Participants With Advanced Urothelial Cancer (MK-3475-045/KEYNOTE-045): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study of Pembrolizumab Plus Epacadostat With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-06/ECHO-306-06): Complete Statistical AnalysisIndependent statistical analysis of A Study of Pembrolizumab Plus Epacadostat With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-06/ECHO-306-06): primary endpoint results, effect estimate…
- A Study of Pemetrexed and Carboplatin/Cisplatin or Gemcitabine and Carboplatin/Cisplatin With or Without IMC-1121B in Participants Previously Untreated With Recurrent or Advanced Non-Small Cell Lung Cancer (NSCLC): Complete Statistical AnalysisIndependent statistical analysis of A Study of Pemetrexed and Carboplatin/Cisplatin or Gemcitabine and Carboplatin/Cisplatin With or Without IMC-1121B in Participants Previously Untreated With Recurrent or Advanced Non-Small Cell Lung Cancer (NSCLC): primary…
- A Study of Pemetrexed and Cyclophosphamide Given Every 21 Days in Advanced Breast Cancer Patients: Complete Statistical AnalysisIndependent statistical analysis of A Study of Pemetrexed and Cyclophosphamide Given Every 21 Days in Advanced Breast Cancer Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study of Pemetrexed in Recurrent Cervical Adenocarcinomas: Complete Statistical AnalysisIndependent statistical analysis of A Study of Pemetrexed in Recurrent Cervical Adenocarcinomas: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02868892).
- A Study of Pertuzumab in Participants With Metastatic Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Pertuzumab in Participants With Metastatic Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02491892).
- A Study of Pertuzumab in Participants With Prostate Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Pertuzumab in Participants With Prostate Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02480010).
- A Study of Pertuzumab With Erlotinib in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC): Complete Statistical AnalysisIndependent statistical analysis of A Study of Pertuzumab With Erlotinib in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems: Complete Statistical AnalysisIndependent statistical analysis of A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study Of PF-04449913 In Japanese Patients With Select Hematologic Malignancies: Complete Statistical AnalysisIndependent statistical analysis of A Study Of PF-04449913 In Japanese Patients With Select Hematologic Malignancies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study Of PF-04449913 In Select Hematologic Malignancies: Complete Statistical AnalysisIndependent statistical analysis of A Study Of PF-04449913 In Select Hematologic Malignancies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00953758).
- A Study Of PF-06647020 For Adult Patients With Advanced Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of A Study Of PF-06647020 For Adult Patients With Advanced Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study Of PF-06664178 In Patients With Advanced Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of A Study Of PF-06664178 In Patients With Advanced Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02122146).
- A Study Of Pharmacokinetics, Whole Body And Organ Dosimetry, And Biodistribution Of Fission-Derived Iodine I 131 Tositumomab (BEXXAR®) For Patients With Previously Untreated Or Relapsed Follicular Or Transformed Non-Hodgkin’s Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study Of Pharmacokinetics, Whole Body And Organ Dosimetry, And Biodistribution Of Fission-Derived Iodine I 131 Tositumomab (BEXXAR®) For Patients With Previously Untreated Or Relapsed Follicular Or Transformed…
- A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia: Complete Statistical AnalysisIndependent statistical analysis of A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of Radiation Therapy and Paclitaxel and Carboplatin in Patients With Uterine Papillary Serous Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Radiation Therapy and Paclitaxel and Carboplatin in Patients With Uterine Papillary Serous Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of Ramucirumab in Participants With Metastatic Renal Cell Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Ramucirumab in Participants With Metastatic Renal Cell Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of Recombinant Vaccinia Virus in Combination With Cemiplimab for Renal Cell Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Recombinant Vaccinia Virus in Combination With Cemiplimab for Renal Cell Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of REGN2810 and Ipilimumab in Patients With Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of REGN2810 and Ipilimumab in Patients With Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of Rituximab (MabThera) in Participants With Chronic Lymphocytic Leukemia (CLL): Complete Statistical AnalysisIndependent statistical analysis of A Study of Rituximab (MabThera) in Participants With Chronic Lymphocytic Leukemia (CLL): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of Sacituzumab With Chemoimmunotherapy to Treat Advanced Triple-Negative Breast Cancer After Prior Therapies: Complete Statistical AnalysisIndependent statistical analysis of A Study of Sacituzumab With Chemoimmunotherapy to Treat Advanced Triple-Negative Breast Cancer After Prior Therapies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study of Safety and Clinical Activity of Immunotherapy Plus Chemotherapy in Metastatic Melanoma Patients: Complete Statistical AnalysisIndependent statistical analysis of A Study of Safety and Clinical Activity of Immunotherapy Plus Chemotherapy in Metastatic Melanoma Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers (Pegathor Skin 201): Complete Statistical AnalysisIndependent statistical analysis of A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers (Pegathor Skin 201): primary endpoint results, effect estimate with confidence interval,…
- A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With HNSCC (Master Protocol) (Pegathor Head and Neck 204): Complete Statistical AnalysisIndependent statistical analysis of A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With HNSCC (Master Protocol) (Pegathor Head and Neck 204): primary endpoint results, effect estimate…
- A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202): Complete Statistical AnalysisIndependent statistical analysis of A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202): primary endpoint results, effect estimate with…
- A Study of Setanaxib Co-Administered With Pembrolizumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN): Complete Statistical AnalysisIndependent statistical analysis of A Study of Setanaxib Co-Administered With Pembrolizumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN): primary endpoint results, effect estimate with confidence…
- A Study of SHR-1210 in Combination With Apatinib or Chemotherapy in Subjects With Advanced PLC or BTC: Complete Statistical AnalysisIndependent statistical analysis of A Study of SHR-1210 in Combination With Apatinib or Chemotherapy in Subjects With Advanced PLC or BTC: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study of Single-Agent Eribulin Mesylate as First-Line Therapy for Locally Recurrent or Metastatic Human Epidermal Growth Factor Receptor Two (HER2) Negative Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Single-Agent Eribulin Mesylate as First-Line Therapy for Locally Recurrent or Metastatic Human Epidermal Growth Factor Receptor Two (HER2) Negative Breast Cancer: primary endpoint results, effect…
- A Study of Sipuleucel-T With Administration of Enzalutamide in Men With Metastatic Castrate-Resistant Prostate Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Sipuleucel-T With Administration of Enzalutamide in Men With Metastatic Castrate-Resistant Prostate Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…