Statistical methods in psychiatry & mental health trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Cochran-Mantel-Haenszel test
Kaplan-Meier estimation
Time-to-event endpoints
Odds ratio
All psychiatry & mental health trials
3 results
- ENGAGEIndependent statistical analysis of the ENGAGE phase 3 trial of aducanumab in early Alzheimer's disease, including randomized trial design, CDR-SB and cognitive endpoints, MMRM methodology, confidence intervals, p-values, and safety.
- EXPEDITION 3Independent statistical analysis of EXPEDITION 3 (NCT01900665), a randomized phase 3 trial comparing solanezumab with placebo in participants with mild Alzheimer's disease, including the registered ADAS-Cog14 endpoint, mixed-effects analysis, confidence interval, p-value,…
- TRAILBLAZER-ALZ 2A detailed statistical analysis of TRAILBLAZER-ALZ 2, a randomized phase 3 study of donanemab versus placebo in participants with early Alzheimer's disease, including endpoint results, mixed-effects models, ANCOVA, confidence intervals, and interpretation.