Statistical methods in respiratory trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Hazard ratio
Mixed-effects model
Odds ratio
Non-inferiority trial design
Cox proportional-hazards model
Logistic regression
Risk difference
All respiratory trials
865 results
- Immunogenicity and Safety Study to Assess Influenza Vaccine Formulated With Haemagglutinin (HA) Antigen From Two Different Suppliers: Complete Statistical AnalysisIndependent statistical analysis of Immunogenicity and Safety Study to Assess Influenza Vaccine Formulated With Haemagglutinin (HA) Antigen From Two Different Suppliers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Immunogenicity of Fluzone HD,A High Dose Influenza Vaccine, In Children With Cancer or HIV: Complete Statistical AnalysisIndependent statistical analysis of Immunogenicity of Fluzone HD,A High Dose Influenza Vaccine, In Children With Cancer or HIV: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Immunogenicity of High-dose Inactivated, Split-virion Influenza Vaccine Versus Standard Fluzone Vaccine in the Elderly: Complete Statistical AnalysisIndependent statistical analysis of Immunogenicity of High-dose Inactivated, Split-virion Influenza Vaccine Versus Standard Fluzone Vaccine in the Elderly: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- IMPACT COPDAn independent statistical analysis of IMPACT COPD (NCT05062304), examining a claims-data replication of COPD therapies and the planned analysis of the annual rate of moderate or severe COPD exacerbations.
- Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block: Complete Statistical AnalysisIndependent statistical analysis of Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Impact of COVID-19 on Marshallese Communities in the U.S.: Complete Statistical AnalysisIndependent statistical analysis of Impact of COVID-19 on Marshallese Communities in the U.S.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04474496).
- Impact of Oxytocin on Obstructive Sleep Apnea Induced Changes in Sleep: Complete Statistical AnalysisIndependent statistical analysis of Impact of Oxytocin on Obstructive Sleep Apnea Induced Changes in Sleep: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- IMPALAIndependent statistical analysis of Efficacy and Safety of Inhaled Molgramostim (rhGM-CSF) in Autoimmune Pulmonary Alveolar Proteinosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- IMPOSEIndependent statistical analysis of Impulse Oscillometry Measurements in Severe Eosinophilic Asthmatics Before and After Anti-IL-5 Factor Initiation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Improving Cognitive Health in COVID-19 Survivors: Complete Statistical AnalysisIndependent statistical analysis of Improving Cognitive Health in COVID-19 Survivors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04843930).
- Improving COVID-19 Vaccine Uptake in Nursing Homes: Complete Statistical AnalysisIndependent statistical analysis of Improving COVID-19 Vaccine Uptake in Nursing Homes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04732819).
- Improving Obstructive Sleep Apnea Management Via Wireless Telemonitoring: Complete Statistical AnalysisIndependent statistical analysis of Improving Obstructive Sleep Apnea Management Via Wireless Telemonitoring: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00682838).
- Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients: Complete Statistical AnalysisIndependent statistical analysis of Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01284140).
- Increasing Influenza and Tdap Vaccination of Pregnant Women: Complete Statistical AnalysisIndependent statistical analysis of Increasing Influenza and Tdap Vaccination of Pregnant Women: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04444518).
- Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis: Complete Statistical AnalysisIndependent statistical analysis of Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Influenza Challenge Study to Determine the Optimal Infection Dose and Safety of a Recombinant H3N2 (A/Texas/71/2017 (H3N2, Clade 3C3a) Influenza Strain: Complete Statistical AnalysisIndependent statistical analysis of Influenza Challenge Study to Determine the Optimal Infection Dose and Safety of a Recombinant H3N2 (A/Texas/71/2017 (H3N2, Clade 3C3a) Influenza Strain: primary endpoint results, effect estimate with confidence…
- Influenza Vaccine in Pregnant Women: Complete Statistical AnalysisIndependent statistical analysis of Influenza Vaccine in Pregnant Women: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00905125).
- Influenza Vaccine Post Allogeneic Transplant: Complete Statistical AnalysisIndependent statistical analysis of Influenza Vaccine Post Allogeneic Transplant: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01215981).
- Inhaled Mannitol as a Mucoactive Therapy for Bronchiectasis: Complete Statistical AnalysisIndependent statistical analysis of Inhaled Mannitol as a Mucoactive Therapy for Bronchiectasis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00669331).
- Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia: Complete Statistical AnalysisIndependent statistical analysis of Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03576885).
- INS-2Independent statistical analysis of Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- InShapeIIIIndependent statistical analysis of CTEPH Identification an Standard Computerised Tomography Pulmonary Angiography in Pulmonary Embolism Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- INSTAGEIndependent statistical analysis of the INSTAGE phase 3 trial of nintedanib co-administered with sildenafil in patients with idiopathic pulmonary fibrosis and advanced lung function impairment, including trial design, endpoints, MMRM methodology, reported…
- Investigate the Impact of Early Treatment Initiation With Tiotropium in Patients Recovering From Hospitalization for an Acute COPD Exacerbation 2: Complete Statistical AnalysisIndependent statistical analysis of Investigate the Impact of Early Treatment Initiation With Tiotropium in Patients Recovering From Hospitalization for an Acute COPD Exacerbation 2: primary endpoint results, effect estimate with confidence interval,…
- Investigation of GSK2879552 in Subjects With Relapsed/Refractory Small Cell Lung Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of Investigation of GSK2879552 in Subjects With Relapsed/Refractory Small Cell Lung Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Investigation of the 24 Hour Forced Expiratory Flow in 1 Second (FEV1) Profile of a Single Dose of Indacaterol/Mometasone Delivered Via the TWISTHALER® Device in Adult Patients With Persistent Asthma: Complete Statistical AnalysisIndependent statistical analysis of Investigation of the 24 Hour Forced Expiratory Flow in 1 Second (FEV1) Profile of a Single Dose of Indacaterol/Mometasone Delivered Via the TWISTHALER® Device in Adult Patients With…
- INVIGORATEIndependent statistical analysis of Exacerbation Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00845728).
- Iota-Carrageenan Nasal Spray in Common Cold: Complete Statistical AnalysisIndependent statistical analysis of Iota-Carrageenan Nasal Spray in Common Cold: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01944631).
- IPF-201Independent statistical analysis of Phase 2a Evaluation of PLN-74809 on αvβ6 Receptor Occupancy Using PET Imaging in Participants With IPF/: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Irinotecan and Carboplatin in Treating Patients With Metastatic or Recurrent Small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of Irinotecan and Carboplatin in Treating Patients With Metastatic or Recurrent Small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- ISABELA1Independent statistical analysis of A Clinical Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care: primary endpoint results,…
- ISABELA2Independent statistical analysis of A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care: primary endpoint results,…
- Juno Perth Clinical Trial: Complete Statistical AnalysisIndependent statistical analysis of Juno Perth Clinical Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02317042).
- KEYNOTE-782Independent statistical analysis of Biomarkers of Response to Pembrolizumab Combined With Chemotherapy in Non-Small Cell Lung Cancer (KEYNOTE-782, MK-3475-782): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- KNOCOUT PEIndependent statistical analysis of An International Pulmonary Embolism Registry Using EKOS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03426124).
- LASORIndependent statistical analysis of Randomized Phase Lll Study of Imatinib Dose Optimization vs Nilotinib in CML Patients With Suboptimal Response to Imatinib: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- LCCC1407Independent statistical analysis of Cisplatin and Nab-paclitaxel for (N2) Defined NSCLC: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02276560).
- LDK378 Versus Chemotherapy in ALK Rearranged (ALK Positive) Patients Previously Treated With Chemotherapy (Platinum Doublet) and Crizotinib: Complete Statistical AnalysisIndependent statistical analysis of LDK378 Versus Chemotherapy in ALK Rearranged (ALK Positive) Patients Previously Treated With Chemotherapy (Platinum Doublet) and Crizotinib: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- LDP0114Independent statistical analysis of Clinical Trial of Efficacy and Safety of Levopront® 30 mg/5 ml in Patients With Dry Cough: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Lenalidomide (Revlimid®) as Second Line Therapy in Patients With Chronic Graft-Vs-Host Disease (GVHD): Complete Statistical AnalysisIndependent statistical analysis of Lenalidomide (Revlimid®) as Second Line Therapy in Patients With Chronic Graft-Vs-Host Disease (GVHD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- LIBERTY ASTHMA QUESTAn independent statistical analysis of the phase 3 LIBERTY ASTHMA QUEST trial of dupilumab 200 mg and 300 mg every two weeks versus matched placebo in persistent asthma, covering negative binomial rate…
- Linsitinib or Topotecan Hydrochloride in Treating Patients With Relapsed Small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of Linsitinib or Topotecan Hydrochloride in Treating Patients With Relapsed Small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- LIPS-A: Lung Injury Prevention Study With Aspirin: Complete Statistical AnalysisIndependent statistical analysis of LIPS-A: Lung Injury Prevention Study With Aspirin: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01504867).
- LiveWellIndependent statistical analysis of DBT for Metastatic Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04973436).
- Long Term Safety of Tobramycin Inhalation Powder in Patients With Cystic Fibrosis: Complete Statistical AnalysisIndependent statistical analysis of Long Term Safety of Tobramycin Inhalation Powder in Patients With Cystic Fibrosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Long-Term Open-Label, Safety Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients: Complete Statistical AnalysisIndependent statistical analysis of Long-Term Open-Label, Safety Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Longitudinal Follow up to Assess Biomarkers Predictive of Emphysema Progression in Patients With COPD (Chronic Obstructive Pulmonary Disease): Complete Statistical AnalysisIndependent statistical analysis of Longitudinal Follow up to Assess Biomarkers Predictive of Emphysema Progression in Patients With COPD (Chronic Obstructive Pulmonary Disease): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- LOVSA statistical analysis and educational interpretation of the LOVS phase 3 randomized trial evaluating lung open ventilation strategies in acute respiratory distress syndrome.
- Lower Dose Chemotherapy Given More Frequent With Avastin to Treat Advanced Non-Squamous Non-Small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of Lower Dose Chemotherapy Given More Frequent With Avastin to Treat Advanced Non-Squamous Non-Small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- LUDICASIndependent statistical analysis of Characteristics of Sexual Dysfunction in Patients With Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06018376).