Respiratory Clinical Trials

Statistical methods in respiratory trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All respiratory trials

865 results

• NAVIGATORIndependent statistical analysis of the phase 3 NAVIGATOR trial (NCT03347279) of tezepelumab 210mg Q4W versus placebo in severe uncontrolled asthma: negative binomial exacerbation rate ratios, mixed-model secondary endpoints, safety and interpretation.Phase 3Results postedn = 1,061NCT03347279
• Nebulized Hypertonic Saline for Inpatient Use in COPD: Complete Statistical AnalysisIndependent statistical analysis of Nebulized Hypertonic Saline for Inpatient Use in COPD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02266875).Phase 4Results postedn = 70NCT02266875
• Nebulized Hypertonic Saline for Mechanically Ventilated Children: Complete Statistical AnalysisIndependent statistical analysis of Nebulized Hypertonic Saline for Mechanically Ventilated Children: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01945944).Phase 1/2Results postedn = 18NCT01945944
• Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma Exacerbation: Complete Statistical AnalysisIndependent statistical analysis of Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma Exacerbation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 4Results postedn = 50NCT01515995
• Neo-DIANA: Neoadjuvant Treatment for EGFR Mutated Patients: Complete Statistical AnalysisIndependent statistical analysis of Neo-DIANA: Neoadjuvant Treatment for EGFR Mutated Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04512430).Phase 2Results postedn = 4NCT04512430
• Neoadjuvant Immunotherapy in Brain Metastases: Complete Statistical AnalysisIndependent statistical analysis of Neoadjuvant Immunotherapy in Brain Metastases: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04434560).Phase 2Results postedn = 1NCT04434560
• NEOMUNIndependent statistical analysis of Neoadjuvant Anti PD-1 Immunotherapy in Resectable Non-small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03197467).Phase 2Results postedn = 30NCT03197467
• NEOSURFIndependent statistical analysis of Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase NAResults postedn = 30NCT02834624
• NEPALIndependent statistical analysis of A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Bronchiectasis: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 2Results postedn = 38NCT00769119
• NETTAn independent statistical analysis of the National Emphysema Treatment Trial (NETT), a randomized phase 3 study of lung volume reduction surgery in emphysema and related obstructive lung disease.Phase 3NCT00000606
• NeuroCovid Rehab and Recovery Related to COVID-19 Diagnosis: Complete Statistical AnalysisIndependent statistical analysis of NeuroCovid Rehab and Recovery Related to COVID-19 Diagnosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04638673).Phase 2Results postedn = 13NCT04638673
• Neuromuscular Electrical Stimulation in Chronic Obstructive Pulmonary Disease (COPD): Complete Statistical AnalysisIndependent statistical analysis of Neuromuscular Electrical Stimulation in Chronic Obstructive Pulmonary Disease (COPD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00677690).Phase 3Results postedn = 83NCT00677690
• Neuroprotective Effects of Lithium in Patients With Small Cell Lung Cancer Undergoing Radiation Therapy to the Brain: Complete Statistical AnalysisIndependent statistical analysis of Neuroprotective Effects of Lithium in Patients With Small Cell Lung Cancer Undergoing Radiation Therapy to the Brain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 1/2Results postedn = 19NCT01553916
• NextCOVEComplete statistical analysis of the phase 3 NextCOVE trial comparing mRNA-1283 with mRNA-1273 for prevention of COVID-19 in participants aged 12 years and older, including non-inferiority methodology, antibody endpoints, COVID-19 efficacy, safety,…Phase 3Results postedn = 13,553NCT05815498
• NIMBLEIndependent statistical analysis of the phase 3 NIMBLE trial (NCT04718389) comparing depemokimab with mepolizumab or benralizumab in severe eosinophilic asthma, including the negative binomial exacerbation rate ratio, non-inferiority logic, ANCOVA secondary endpoints…Phase 3Results postedn = 1,717NCT04718389
• Nitrous Oxide for Identifying the Intersegmental Plane in Segmentectomy: A Randomized Controlled Trial: Complete Statistical AnalysisIndependent statistical analysis of Nitrous Oxide for Identifying the Intersegmental Plane in Segmentectomy: A Randomized Controlled Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 81NCT04302350
• NIXIndependent statistical analysis of the phase 3 NIX trial evaluating bedaquiline, PA-824, and linezolid in participants with drug-resistant pulmonary tuberculosis, including trial design, the bacteriologic and clinical treatment-failure endpoint, planned statistical interpretation,…Phase 3Results postedn = 109NCT02333799
• NO-ASPIRATEIndependent statistical analysis of Oral Suction Intervention to Reduce Aspiration and Ventilator Events: NO-ASPIRATE: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02284178).Phase NAResults postedn = 513NCT02284178
• Non Invasive Ventilation as Airway Clearance in Patients With Cystic Fibrosis: Complete Statistical AnalysisIndependent statistical analysis of Non Invasive Ventilation as Airway Clearance in Patients With Cystic Fibrosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 32NCT02083263
• Non-Contrast 4DCT to Detect Pulmonary Thromboembolic Events: Complete Statistical AnalysisIndependent statistical analysis of Non-Contrast 4DCT to Detect Pulmonary Thromboembolic Events: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03183063).Phase NAResults postedn = 139NCT03183063
• Non-Invasive Ventilation Via a Helmet Device for Patients Respiratory Failure: Complete Statistical AnalysisIndependent statistical analysis of Non-Invasive Ventilation Via a Helmet Device for Patients Respiratory Failure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01680783).Phase NAResults postedn = 83NCT01680783
• NOTUSIndependent statistical analysis of the phase 3 NOTUS trial of dupilumab versus placebo in moderate to severe COPD with type 2 inflammation: negative binomial exacerbation-rate analysis, MMRM lung-function and SGRQ results, hierarchical…Phase 3Results postedn = 935NCT04456673
• NOVA2Independent statistical analysis of Inhaled Nitric Oxide and Neuroprotection in Premature Infants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00515281).Phase 2/3Results postedn = 273NCT00515281
• Novel Management of Airway Protection in Parkinson’s Disease: A Clinical Trial: Complete Statistical AnalysisIndependent statistical analysis of Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 2Results postedn = 65NCT02927691
• Novel Optical Surface Image Guidance System for Beam-Gated Online Adaptive SBRT Delivery in Mobile Lower Lung and Upper Abdominal Malignancies: Complete Statistical AnalysisIndependent statistical analysis of Novel Optical Surface Image Guidance System for Beam-Gated Online Adaptive SBRT Delivery in Mobile Lower Lung and Upper Abdominal Malignancies: primary endpoint results, effect estimate with confidence interval,…Phase NAResults postedn = 10NCT05030454
• NSCLCIndependent statistical analysis of Multicenter Study of Rociletinib Administered to Patients With Previously Treated Mutant EGFR Non-small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 318NCT02147990
• NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours: Complete Statistical AnalysisIndependent statistical analysis of NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 1/2Results postedn = 19NCT05714553
• Nurse Coach-Led Early Palliative Care for Older Adults With COPD and Their Care Partners: The Project EPIC Pilot RCT: Complete Statistical AnalysisIndependent statistical analysis of Nurse Coach-Led Early Palliative Care for Older Adults With COPD and Their Care Partners: The Project EPIC Pilot RCT: primary endpoint results, effect estimate with confidence interval, sample-size…Phase NAResults postedn = 50NCT05040386
• OAKTREEComplete statistical analysis of the randomized phase 3 OAKTREE trial of obeldesivir in nonhospitalized participants with COVID-19, including trial design, endpoints, survival analysis, viral-load analysis, safety, statistical methodology, results, and interpretation.Phase 3Results postedn = 2,011NCT05715528
• Obesity, Sleep Apnea, and Insulin Resistance: Complete Statistical AnalysisIndependent statistical analysis of Obesity, Sleep Apnea, and Insulin Resistance: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02192684).Phase NAResults postedn = 45NCT02192684
• Obstructive Sleep Apnea in World Trade Center Responders: Complete Statistical AnalysisIndependent statistical analysis of Obstructive Sleep Apnea in World Trade Center Responders: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01753999).Phase NAResults postedn = 317NCT01753999
• Occurrence of Potential Bacterial and Viral Pathogens in Stable Chronic Obstructive Pulmonary Disease and During Acute Exacerbations of the Disease, in Asia Pacific: Complete Statistical AnalysisIndependent statistical analysis of Occurrence of Potential Bacterial and Viral Pathogens in Stable Chronic Obstructive Pulmonary Disease and During Acute Exacerbations of the Disease, in Asia Pacific: primary endpoint results, effect estimate…Phase NAResults postedn = 197NCT03151395
• Olopatadine Eye Drops and Allergy Skin Testing: Complete Statistical AnalysisIndependent statistical analysis of Olopatadine Eye Drops and Allergy Skin Testing: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00775658).Phase NAResults postedn = 24NCT00775658
• Omalizumab in Patients With Moderate to Severe Persistent Allergic Asthma Not Adequately Controlled Despite GINA (2009) Step 4 Therapy: Complete Statistical AnalysisIndependent statistical analysis of Omalizumab in Patients With Moderate to Severe Persistent Allergic Asthma Not Adequately Controlled Despite GINA (2009) Step 4 Therapy: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 616NCT01202903
• Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive Patients: Complete Statistical AnalysisIndependent statistical analysis of Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase NAResults postedn = 2NCT04748120
• Optiflow THRIVE for Delivery of Oxygen to Patients During Total Intravenous Anesthesia While Undergoing Radiology Procedures: Complete Statistical AnalysisIndependent statistical analysis of Optiflow THRIVE for Delivery of Oxygen to Patients During Total Intravenous Anesthesia While Undergoing Radiology Procedures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase NAResults postedn = 108NCT04171037
• OPTIMISEIndependent statistical analysis of Occipital Nerve Stimulation (ONS) for Migraine: OPTIMISE: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01775735).Phase NAResults postedn = 28NCT01775735
• OPTIMIZEComplete statistical analysis of the OPTIMIZE phase 3 trial of roflumilast dosing as add-on to standard COPD treatment in severe COPD, including trial design, discontinuation endpoints, logistic and Cox regression, adverse events,…Phase 3Results postedn = 1,323NCT02165826
• Optimizing and Standardizing 129Xe Gas Exchange MRI to Visualize Regional Therapy Response in Interstitial Lung Disease: Complete Statistical AnalysisIndependent statistical analysis of Optimizing and Standardizing 129Xe Gas Exchange MRI to Visualize Regional Therapy Response in Interstitial Lung Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 47NCT04855305
• Optimizing Self-management COPD Treatment Through the American Lung Association Helpline: Complete Statistical AnalysisIndependent statistical analysis of Optimizing Self-management COPD Treatment Through the American Lung Association Helpline: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05106257).Phase NAResults postedn = 46NCT05106257
• Oral Ifetroban to Treat Aspirin Exacerbated Respiratory Disease (AERD): Complete Statistical AnalysisIndependent statistical analysis of Oral Ifetroban to Treat Aspirin Exacerbated Respiratory Disease (AERD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03028350).Phase 2Results postedn = 54NCT03028350
• Oral Paricalcitol in Kidney Transplant Recipients: Complete Statistical AnalysisIndependent statistical analysis of Oral Paricalcitol in Kidney Transplant Recipients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00587158).Phase NAResults postedn = 100NCT00587158
• ORBIT-3Independent statistical analysis of the randomized phase 3 ORBIT-3 trial evaluating ciprofloxacin dispersion for inhalation in non-CF bronchiectasis, including trial design, time-to-first-exacerbation methodology, planned analysis, and statistical interpretation.Phase 3n = 278NCT01515007
• Osimertinib for NSCLC With EGFR Exon 20 Insertion Mutation: Complete Statistical AnalysisIndependent statistical analysis of Osimertinib for NSCLC With EGFR Exon 20 Insertion Mutation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03414814).Phase 2Results postedn = 15NCT03414814
• OSTROIndependent statistical analysis of Efficacy and Safety Study of Benralizumab for Patients With Severe Nasal Polyposis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 3Results postedn = 413NCT03401229
• Outlook Quality of Life Intervention: Complete Statistical AnalysisIndependent statistical analysis of Outlook Quality of Life Intervention: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00784095).Phase NAResults postedn = 36NCT00784095
• Oxaliplatin and Docetaxel as First-line Therapy for Advanced Non-small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of Oxaliplatin and Docetaxel as First-line Therapy for Advanced Non-small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 15NCT00145418
• Oxidative Stress in Asthma: Complete Statistical AnalysisIndependent statistical analysis of Oxidative Stress in Asthma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04512547).Phase 2Results postedn = 49NCT04512547
• Oxygen Monitoring of Patients After Surgery on the Hospital General Care Floor: Complete Statistical AnalysisIndependent statistical analysis of Oxygen Monitoring of Patients After Surgery on the Hospital General Care Floor: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase NAResults postedn = 100NCT01082575
• PA-824-CL-007: Phase IIa Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis: Complete Statistical AnalysisIndependent statistical analysis of PA-824-CL-007: Phase IIa Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 2Results postedn = 69NCT00567840

← All therapeutic areas