Respiratory Clinical Trials

Statistical methods in respiratory trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All respiratory trials

865 results

• Photodynamic Therapy Using HPPH in Treating Patients With Advanced Non-Small Cell Lung Cancer That Blocks the Air Passages: Complete Statistical AnalysisIndependent statistical analysis of Photodynamic Therapy Using HPPH in Treating Patients With Advanced Non-Small Cell Lung Cancer That Blocks the Air Passages: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 2Results postedn = 6NCT00528775
• PICASSOIndependent statistical analysis of A Study to Learn About the Safety and Immune Activity of RSVpreF in Children 2 toPhase 1Results postedn = 128NCT05900154
• PiiitchIndependent statistical analysis of Feasibility of Cocooning Immunization Strategy With Influenza Vaccine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00570037).Phase NAResults postedn = 544NCT00570037
• PIIPPIIndependent statistical analysis of COVID-19: Povidone-Iodine Intranasal Prophylaxis in Front-line Healthcare Personnel and Inpatients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04364802).Phase 2Results postedn = 98NCT04364802
• Pilot and Feasibility Study for the Treatment of Pre-diabetes in Patients With Cystic Fibrosis: Complete Statistical AnalysisIndependent statistical analysis of Pilot and Feasibility Study for the Treatment of Pre-diabetes in Patients With Cystic Fibrosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase NAResults postedn = 31NCT00763412
• Pilot Study About the Harmful Effects of Blood Storage on Overweight People and the Role of iNO in This Setting: Complete Statistical AnalysisIndependent statistical analysis of Pilot Study About the Harmful Effects of Blood Storage on Overweight People and the Role of iNO in This Setting: primary endpoint results, effect estimate with confidence interval,…Phase 2Results postedn = 14NCT01529502
• Piloting ‘mPal,’ a Multilevel Strategy for Palliative Care Implementation: Complete Statistical AnalysisIndependent statistical analysis of Piloting 'mPal,' a Multilevel Strategy for Palliative Care Implementation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05270395).Phase NAResults postedn = 75NCT05270395
• PIONEERIndependent statistical analysis of the phase 2 PIONEER trial of CHF6001 in chronic obstructive pulmonary disease, including trial design, the primary FEV1 endpoint, planned statistical analysis, and interpretation.Phase 2n = 1,130NCT02986321
• Pivotal, Multicenter, Observer-Blind, Randomized Study of Influenza A (H1N1)2009 Monovalent Subunit Vaccine With and Without Adjuvant in Children Ages 6 to <36 Months: Complete Statistical AnalysisIndependent statistical analysis of Pivotal, Multicenter, Observer-Blind, Randomized Study of Influenza A (H1N1)2009 Monovalent Subunit Vaccine With and Without Adjuvant in Children Ages 6 toPhase 2/3Results postedn = 654NCT00996307
• Placebo In Chronic Back Pain – Double-Blind Randomized Control Trial: Complete Statistical AnalysisIndependent statistical analysis of Placebo In Chronic Back Pain - Double-Blind Randomized Control Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02013427).Phase 4Results postedn = 82NCT02013427
• Placebo-Controlled Trial of Antibiotic Therapy in Adults With Suspect Lower Respiratory Tract Infection (LRTI) and a Procalcitonin Level: Complete Statistical AnalysisIndependent statistical analysis of Placebo-Controlled Trial of Antibiotic Therapy in Adults With Suspect Lower Respiratory Tract Infection (LRTI) and a Procalcitonin Level: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase NAResults postedn = 514NCT03341273
• Plasma Therapy of COVID-19 in Severely Ill Patients: Complete Statistical AnalysisIndependent statistical analysis of Plasma Therapy of COVID-19 in Severely Ill Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04359810).Phase 2Results postedn = 223NCT04359810
• Platinum-Based Chemotherapy Plus Ramucirumab in Patients With Advanced NSCLC Who Have Progressed on First Line Anti-PD-1 Immunotherapy: Complete Statistical AnalysisIndependent statistical analysis of Platinum-Based Chemotherapy Plus Ramucirumab in Patients With Advanced NSCLC Who Have Progressed on First Line Anti-PD-1 Immunotherapy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 3NCT03904108
• PleuraSeal Post Market Study (Europe): Complete Statistical AnalysisIndependent statistical analysis of PleuraSeal Post Market Study (Europe): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00704171).Phase 4Results postedn = 121NCT00704171
• Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate: Complete Statistical AnalysisIndependent statistical analysis of Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00165503).Phase 2Results postedn = 16NCT00165503
• PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell Cancers: Complete Statistical AnalysisIndependent statistical analysis of PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell Cancers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 1/2Results postedn = 10NCT04209595
• POET-COPDIndependent statistical analysis of POET-COPD (NCT05083429), a completed study comparing salmeterol and tiotropium for time to first COPD exacerbation in chronic obstructive pulmonary disease.n = 8,716NCT05083429
• Post-authorisation Passive Enhanced Safety Surveillance of Seasonal Influenza Vaccines: Pilot Study in England: Complete Statistical AnalysisIndependent statistical analysis of Post-authorisation Passive Enhanced Safety Surveillance of Seasonal Influenza Vaccines: Pilot Study in England: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 23,939NCT03278067
• Post-licensure, Modified Double-blind, Multi-center Study Evaluating Safety and Immunogenicity of ADACEL® and BOOSTRIX®: Complete Statistical AnalysisIndependent statistical analysis of Post-licensure, Modified Double-blind, Multi-center Study Evaluating Safety and Immunogenicity of ADACEL® and BOOSTRIX®: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 4Results postedn = 647NCT00319553
• Precision Approach to PPI Therapy in Gastroesophageal Reflux Disease: Complete Statistical AnalysisIndependent statistical analysis of Precision Approach to PPI Therapy in Gastroesophageal Reflux Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03619811).Phase NAResults postedn = 43NCT03619811
• Preference Attributes of ELLIPTA Dry Powder Inhaler (DPI) and HANDIHALER DPI in Subjects With Chronic Obstructive Pulmonary Disease (COPD): Complete Statistical AnalysisIndependent statistical analysis of Preference Attributes of ELLIPTA Dry Powder Inhaler (DPI) and HANDIHALER DPI in Subjects With Chronic Obstructive Pulmonary Disease (COPD): primary endpoint results, effect estimate with confidence interval, sample-size…Phase 4Results postedn = 214NCT02786927
• Preoperative Pemetrexed and Carboplatin for Select Stage IB, II, and III Non-Squamous Non-Small-Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of Preoperative Pemetrexed and Carboplatin for Select Stage IB, II, and III Non-Squamous Non-Small-Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 2Results postedn = 46NCT00906282
• PREVAILIndependent statistical analysis of A Phase 2 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Patients With Multi-Site Pain Associated With Post-Acute Sequelae of SARS-CoV-2 Infection: primary endpoint results,…Phase 2Results postedn = 63NCT05472090
• PREVENTIndependent statistical analysis of Improving Patient Prioritization During Hospital-homecare Transition: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04136951).Phase NAResults postedn = 1,915NCT04136951
• PREVENTIndependent statistical analysis of Prazosin to Prevent COVID-19 (PREVENT-COVID Trial): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04365257).Phase 2Results postedn = 5NCT04365257
• PREVENT-HDA detailed statistical analysis of the phase 3 PREVENT-HD trial of rivaroxaban versus placebo in medically ill outpatients with acute symptomatic COVID-19 infection, including its time-to-event endpoints, hazard ratio, confidence interval, log-rank…Phase 3Results postedn = 1,284NCT04508023
• PREVENT-HDIndependent statistical analysis of A Study of Rivaroxaban to Reduce the Risk of Major Venous and Arterial Thrombotic Events, Hospitalization and Death in Medically Ill Outpatients With Acute, Symptomatic Coronavirus Disease 2019…Phase 3Results postedn = 1,284NCT04508023
• Prevention of Altitude Illness With Non-steroidal Anti-inflammatory Study (PAINS): Complete Statistical AnalysisIndependent statistical analysis of Prevention of Altitude Illness With Non-steroidal Anti-inflammatory Study (PAINS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01171794).Phase 3Results postedn = 89NCT01171794
• Problem-Solving Skills Training to Improve Care for Children With Asthma: Complete Statistical AnalysisIndependent statistical analysis of Problem-Solving Skills Training to Improve Care for Children With Asthma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00250588).Phase NAResults postedn = 252NCT00250588
• Prolonged Prone Positioning for COVID-19-induced Acute Respiratory Distress Syndrome (ARDS): Complete Statistical AnalysisIndependent statistical analysis of Prolonged Prone Positioning for COVID-19-induced Acute Respiratory Distress Syndrome (ARDS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04581811).Phase NAResults postedn = 52NCT04581811
• PROMIS-IIAn independent statistical analysis of PROMIS-II, a phase 3 placebo-controlled trial of colistimethate sodium in non-cystic fibrosis bronchiectasis, explaining the negative binomial analysis of the annual pulmonary exacerbation rate and its rate…Phase 3Results postedn = 287NCT03460704
• Promoting Altruism to Enhance Vaccine Acceptance: Complete Statistical AnalysisIndependent statistical analysis of Promoting Altruism to Enhance Vaccine Acceptance: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04568590).Phase NAResults postedn = 510NCT04568590
• Propel Stent vs Kenalog-soaked Nasopore After Frontal Drill-out: Complete Statistical AnalysisIndependent statistical analysis of Propel Stent vs Kenalog-soaked Nasopore After Frontal Drill-out: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03534362).Phase NAResults postedn = 1NCT03534362
• Prophylactic Efficacy of Relenza Against Influenza A and B: Complete Statistical AnalysisIndependent statistical analysis of Prophylactic Efficacy of Relenza Against Influenza A and B: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01156701).Phase NAResults postedn = 171,705NCT01156701
• Prophylactic nCPAP Following Bowel Surgery (Bio-REB File 11-27): Complete Statistical AnalysisIndependent statistical analysis of Prophylactic nCPAP Following Bowel Surgery (Bio-REB File 11-27): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01316575).Phase NAResults postedn = 40NCT01316575
• PROSEVAIndependent statistical analysis of the PROSEVA randomized trial of prone positioning in patients with severe and persistent acute respiratory distress syndrome, including trial design, mortality endpoint, planned statistical analysis, and interpretation.Phase NAn = 474NCT00527813
• PROVENTIndependent statistical analysis of Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 3Results postedn = 5,197NCT04625725
• Pulmonary Function After Hyperbaric Oxygen Therapy: Complete Statistical AnalysisIndependent statistical analysis of Pulmonary Function After Hyperbaric Oxygen Therapy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05088772).Phase NAResults postedn = 86NCT05088772
• PULSARIndependent statistical analysis of A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (PAH): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 106NCT03496207
• Pupillary Unrest as an Indicator of Central Opioid Effect in Subjects 40-60 Years of Age: Complete Statistical AnalysisIndependent statistical analysis of Pupillary Unrest as an Indicator of Central Opioid Effect in Subjects 40-60 Years of Age: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 2/3Results postedn = 10NCT05391555
• PXD101 as Second-Line Therapy in Treating Patients With Malignant Mesothelioma of the Chest That Cannot Be Removed By Surgery: Complete Statistical AnalysisIndependent statistical analysis of PXD101 as Second-Line Therapy in Treating Patients With Malignant Mesothelioma of the Chest That Cannot Be Removed By Surgery: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 2Results postedn = 13NCT00365053
• QUALIFY IPFIndependent statistical analysis of Investigating Trends in Quality of Life in Patients With Idiopathic Pulmonary Fibrosis (IPF) Under Treatment With Nintedanib: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase NAResults postedn = 180NCT03710824
• QUARTZIndependent statistical analysis of QUARTZ, an observational study comparing severe asthma exacerbation rates among cohorts receiving Airsupra or alternative rescue-treatment strategies.n = 8,000NCT07787117
• QUILT-3.040: ETBX-011 (Ad5 [E1-, E2b-]-CEA(6D)) Vaccine in Combination With ALT-803 (Super-agonist IL-15) in Subjects Having CEA-Expressing Cancer: Complete Statistical AnalysisIndependent statistical analysis of QUILT-3.040: ETBX-011 (Ad5 [E1-, E2b-]-CEA(6D)) Vaccine in Combination With ALT-803 (Super-agonist IL-15) in Subjects Having CEA-Expressing Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 1/2Results postedn = 3NCT03127098
• Randomised, Double- Blind, Cross-over Efficacy and Safety Comparison of Three Different Doses of Tiotropium Administered Once Daily Versus Placebo in Patients With Moderate Persistent Asthma.: Complete Statistical AnalysisIndependent statistical analysis of Randomised, Double- Blind, Cross-over Efficacy and Safety Comparison of Three Different Doses of Tiotropium Administered Once Daily Versus Placebo in Patients With Moderate Persistent Asthma.: primary endpoint results,…Phase 2Results postedn = 149NCT01233284
• Randomized Controlled Trial of Talc Instillation In Addition To Daily Drainage Through a Tunneled Pleural Catheter to Improve Rates of Outpatient Pleurodesis in Patients With Malignant Pleural Effusion: Complete Statistical AnalysisIndependent statistical analysis of Randomized Controlled Trial of Talc Instillation In Addition To Daily Drainage Through a Tunneled Pleural Catheter to Improve Rates of Outpatient Pleurodesis in Patients With Malignant Pleural Effusion:…Phase 4Results postedn = 4NCT04792970
• Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the Lungs: Complete Statistical AnalysisIndependent statistical analysis of Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the Lungs: primary endpoint results, effect estimate…Phase 2Results postedn = 104NCT03896503
• Randomized, Placebo-Controlled, Multidose, Study Comparing Generic Budesonide/Formoterol Fumarate Dihydrate to Symbicort® in Asthmatic Participants: Complete Statistical AnalysisIndependent statistical analysis of Randomized, Placebo-Controlled, Multidose, Study Comparing Generic Budesonide/Formoterol Fumarate Dihydrate to Symbicort® in Asthmatic Participants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 3Results postedn = 1,714NCT02495168
• Rapid Switch From Flolan to Remodulin in the Outpatient Clinic: Complete Statistical AnalysisIndependent statistical analysis of Rapid Switch From Flolan to Remodulin in the Outpatient Clinic: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00643604).Phase 4Results postedn = 7NCT00643604
• REACH 5Independent statistical analysis of Activity, Safety and Pharmacokinetics in Pediatric Subjects With Moderate and Severe Chronic Graft vs. Host Disease After Allogeneic Stem Cell Transplant: primary endpoint results, effect estimate with confidence…Phase 2Results postedn = 46NCT03774082

← All therapeutic areas