Respiratory Clinical Trials

Statistical methods in respiratory trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All respiratory trials

625 results

• A Study of Trastuzumab Emtansine in Participants With Human Epidermal Growth Factor Receptor (HER)2 Immunohistochemistry (IHC)-Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC): Complete Statistical AnalysisIndependent statistical analysis of A Study of Trastuzumab Emtansine in Participants With Human Epidermal Growth Factor Receptor (HER)2 Immunohistochemistry (IHC)-Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC): primary endpoint results,…Phase 2Results postedn = 49NCT02289833
• A Study of Treprostinil to Treat Interstitial Lung Disease Pulmonary Hypertension: Complete Statistical AnalysisIndependent statistical analysis of A Study of Treprostinil to Treat Interstitial Lung Disease Pulmonary Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 2Results postedn = 29NCT05564637
• A Study of V419 Given Concomitantly With Prevnar 13™ and RotaTeq™ (V419-006): Complete Statistical AnalysisIndependent statistical analysis of A Study of V419 Given Concomitantly With Prevnar 13™ and RotaTeq™ (V419-006): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 3Results postedn = 2,808NCT01340937
• A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults: Complete Statistical AnalysisIndependent statistical analysis of A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 1/2Results postedn = 45NCT00745251
• A Study on the Immune Response and Safety of the Shingles Vaccine and the Influenza Vaccine When Either is Given to Healthy Adults at the Same Time or Following a COVID-19 Booster Vaccine: Complete Statistical AnalysisIndependent statistical analysis of A Study on the Immune Response and Safety of the Shingles Vaccine and the Influenza Vaccine When Either is Given to Healthy Adults at the Same Time or…Phase 3Results postedn = 2,013NCT05047770
• A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 1/2Results postedn = 48NCT04424641
• A Study To Assess Efficacy And Safety Of Different Doses Of GW642444 In Subjects With Chronic Obstructive Pulmonary Disease (COPD): Complete Statistical AnalysisIndependent statistical analysis of A Study To Assess Efficacy And Safety Of Different Doses Of GW642444 In Subjects With Chronic Obstructive Pulmonary Disease (COPD): primary endpoint results, effect estimate with confidence interval,…Phase 2Results postedn = 602NCT00606684
• A Study To Assess Single Dosage Strength Of GW685698/GW642444 Chronic Obstructive Pulmonary Disease (COPD): Complete Statistical AnalysisIndependent statistical analysis of A Study To Assess Single Dosage Strength Of GW685698/GW642444 Chronic Obstructive Pulmonary Disease (COPD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 2Results postedn = 60NCT00731822
• A Study to Assess the Effect of CK-2127107 on Physical Function in Subjects With Chronic Obstructive Pulmonary Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Effect of CK-2127107 on Physical Function in Subjects With Chronic Obstructive Pulmonary Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 2Results postedn = 46NCT02662582
• A Study to Assess the Safety and Efficacy of Treprostinil to Facilitate Liver Transplantation in Patients With Portopulmonary Hypertension: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Safety and Efficacy of Treprostinil to Facilitate Liver Transplantation in Patients With Portopulmonary Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size…Phase NAResults postedn = 13NCT01028651
• A Study to Assess the Safety and Tolerability of N-Acetylcysteine When Administered With Pirfenidone to Participants With Idiopathic Pulmonary Fibrosis (IPF): Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Safety and Tolerability of N-Acetylcysteine When Administered With Pirfenidone to Participants With Idiopathic Pulmonary Fibrosis (IPF): primary endpoint results, effect estimate with confidence…Phase 2Results postedn = 123NCT02707640
• A Study to Assess the Safety and Tolerability of Once Daily Inhaled Doses of GSK573719 Made With Magnesium Stearate in Subjects With Chronic Obstructive Pulmonary Disease(COPD)for 7 Days: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Safety and Tolerability of Once Daily Inhaled Doses of GSK573719 Made With Magnesium Stearate in Subjects With Chronic Obstructive Pulmonary Disease(COPD)for 7 Days:…Phase 2Results postedn = 37NCT00732472
• A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Brensocatib Tablets in Adults With Cystic Fibrosis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Brensocatib Tablets in Adults With Cystic Fibrosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 29NCT05090904
• A Study to Compare the Efficacy and Safety of Umeclidinium/Vilanterol and Fluticasone Propionate/Salmeterol in Subjects With Chronic Obstructive Pulmonary Disease (COPD): Complete Statistical AnalysisIndependent statistical analysis of A Study to Compare the Efficacy and Safety of Umeclidinium/Vilanterol and Fluticasone Propionate/Salmeterol in Subjects With Chronic Obstructive Pulmonary Disease (COPD): primary endpoint results, effect estimate with confidence…Phase 3Results postedn = 707NCT01817764
• A Study to Evaluate Safety, Tolerability, & Immunogenicity of Multiple Formulations of BNT162b2 Against COVID-19 in Healthy Adults: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate Safety, Tolerability, & Immunogenicity of Multiple Formulations of BNT162b2 Against COVID-19 in Healthy Adults: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 3Results postedn = 629NCT04816669
• A Study to Evaluate the 24 Hour Spirometric Effect (FEV1) of Fluticasone Furoate/Vilanterol Inhalation Powder (100mcg Fluticasone Furoate (FF)/25mcg Vilanterol (VI)) Compared With Salmeterol/Fluticasone Propionate Inhalation Powder (50mcg Salmeterol/500mcg Fluticasone Propionate (FP)): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the 24 Hour Spirometric Effect (FEV1) of Fluticasone Furoate/Vilanterol Inhalation Powder (100mcg Fluticasone Furoate (FF)/25mcg Vilanterol (VI)) Compared With Salmeterol/Fluticasone Propionate Inhalation Powder (50mcg…Phase 3Results postedn = 528NCT01342913
• A Study to Evaluate the Effect of a Single-Dose Intravenous Administration of MEDI-528: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effect of a Single-Dose Intravenous Administration of MEDI-528: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 2Results postedn = 11NCT00483041
• A Study to Evaluate the Effect of Umeclidinium (UMEC) as Combination Therapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effect of Umeclidinium (UMEC) as Combination Therapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD): primary endpoint results, effect estimate with confidence interval,…Phase 4Results postedn = 236NCT02257372
• A Study to Evaluate the Efficacy and Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 1,334NCT05037929
• A Study to Evaluate the Efficacy and Safety of Fluticasone Furoate (FF)/GW642444 Inhalation Powder in Subjects With Chronic Obstructive Pulmonary Disease (COPD): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of Fluticasone Furoate (FF)/GW642444 Inhalation Powder in Subjects With Chronic Obstructive Pulmonary Disease (COPD): primary endpoint results, effect estimate with…Phase 3Results postedn = 1,626NCT01009463
• A Study to Evaluate the Efficacy and Safety of Reslizumab (0.3 or 3.0 mg/kg) as Treatment for Patients (12-75 Years of Age) With Eosinophilic Asthma: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of Reslizumab (0.3 or 3.0 mg/kg) as Treatment for Patients (12-75 Years of Age) With Eosinophilic Asthma: primary endpoint results,…Phase 3Results postedn = 315NCT01270464
• A Study to Evaluate the Efficacy and Safety of Reslizumab (3.0 mg/kg) in the Reduction of Clinical Asthma Exacerbations in Patients (12-75 Years of Age) With Eosinophilic Asthma: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of Reslizumab (3.0 mg/kg) in the Reduction of Clinical Asthma Exacerbations in Patients (12-75 Years of Age) With Eosinophilic Asthma:…Phase 3Results postedn = 489NCT01287039
• A Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR Mutation: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR…Phase 3Results postedn = 168NCT02516410
• A Study to Evaluate the Immunogenicity and Safety of Seqirus Quadrivalent Influenza Vaccine (QIV) in a Pediatric Population 5 Through 17 Years of Age: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Immunogenicity and Safety of Seqirus Quadrivalent Influenza Vaccine (QIV) in a Pediatric Population 5 Through 17 Years of Age: primary endpoint results, effect…Phase 3Results postedn = 2,278NCT02545543
• A Study to Evaluate the Immunogenicity and Safety of Seqirus Quadrivalent Influenza Vaccine (QIV) in a Pediatric Population 6 Months Through 59 Months of Age.: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Immunogenicity and Safety of Seqirus Quadrivalent Influenza Vaccine (QIV) in a Pediatric Population 6 Months Through 59 Months of Age.: primary endpoint results,…Phase 3Results postedn = 2,250NCT02914275
• A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Perennial Allergies: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Perennial Allergies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 581NCT00712920
• A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 506NCT00824473
• A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 2Results postedn = 173NCT00955279
• A Study to Evaluate the Safety and Efficacy of AVTX-002 for the Treatment of Poorly Controlled Non-Eosinophilic Asthma.: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Efficacy of AVTX-002 for the Treatment of Poorly Controlled Non-Eosinophilic Asthma.: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 2Results postedn = 91NCT05288504
• A Study to Evaluate the Safety of Combination Montelukast/Loratadine in Mexican Participants With Allergic Rhinitis (MK-0476A-484): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety of Combination Montelukast/Loratadine in Mexican Participants With Allergic Rhinitis (MK-0476A-484): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 69NCT01673620
• A Study to Evaluate the Safety, Tolerability, and Antitumor Activity of INCB001158 Plus Epacadostat, With or Without Pembrolizumab, in Advanced Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety, Tolerability, and Antitumor Activity of INCB001158 Plus Epacadostat, With or Without Pembrolizumab, in Advanced Solid Tumors: primary endpoint results, effect estimate with…Phase 1/2Results postedn = 5NCT03361228
• A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Inhaled Montelukast (MK-0476) in Participants With Mild or Moderate Asthma (MK-0476-380 AM3)(COMPLETED): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Inhaled Montelukast (MK-0476) in Participants With Mild or Moderate Asthma (MK-0476-380 AM3)(COMPLETED): primary endpoint results, effect estimate with…Phase 1Results postedn = 46NCT00636207
• A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF): Complete Statistical AnalysisIndependent statistical analysis of A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF): primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 3Results postedn = 1,177NCT05321069
• A Study to Find the Dose and Assess the Immune Response and Safety of a Vaccine Against Influenza in Healthy Younger and Older Adults: Complete Statistical AnalysisIndependent statistical analysis of A Study to Find the Dose and Assess the Immune Response and Safety of a Vaccine Against Influenza in Healthy Younger and Older Adults: primary endpoint results, effect…Phase 2Results postedn = 845NCT06431607
• A Study to Investigate the Pharmacokinetics, Efficacy and Safety of INM005 in Patients With COVID-19.: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate the Pharmacokinetics, Efficacy and Safety of INM005 in Patients With COVID-19.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 2/3Results postedn = 243NCT04494984
• A Study To Investigate The Pharmacokinetics, Safety And Tolerability Of An Intravenous And Oral Form Of A Compound In Subjects With Varying Degrees Of Renal Impairment And Normal Renal Function: Complete Statistical AnalysisIndependent statistical analysis of A Study To Investigate The Pharmacokinetics, Safety And Tolerability Of An Intravenous And Oral Form Of A Compound In Subjects With Varying Degrees Of Renal Impairment And Normal…Phase 1Results postedn = 29NCT00759564
• A Study to Learn About New COVD-19 RNA Vaccine Candidates for New Variants in Healthy Individuals: Complete Statistical AnalysisIndependent statistical analysis of A Study to Learn About New COVD-19 RNA Vaccine Candidates for New Variants in Healthy Individuals: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2/3Results postedn = 1,051NCT05997290
• A Study to Look at Day to Day Changes in Lung Function in COPD Subjects Taking Albuterol/Salbutamol and Ipratropium: Complete Statistical AnalysisIndependent statistical analysis of A Study to Look at Day to Day Changes in Lung Function in COPD Subjects Taking Albuterol/Salbutamol and Ipratropium: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 4Results postedn = 56NCT01691482
• A Study to Test How Taking BI 1015550 for 12 Weeks Affects Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF): Complete Statistical AnalysisIndependent statistical analysis of A Study to Test How Taking BI 1015550 for 12 Weeks Affects Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF): primary endpoint results, effect estimate with confidence…Phase 2Results postedn = 147NCT04419506
• A Time-motion Study Comparing Self- to Nurse-vaccination With Influenza Vaccine: Complete Statistical AnalysisIndependent statistical analysis of A Time-motion Study Comparing Self- to Nurse-vaccination With Influenza Vaccine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01665807).Phase 4Results postedn = 868NCT01665807
• A Trial Comparing Safety and Efficacy of Carboplatin and Paclitaxel Plus or Minus Sorafenib (BAY43-9006) in Chemonaive Patients With Stage IIIB-IV Non-Small Cell Lung Cancer (NSCLC): Complete Statistical AnalysisIndependent statistical analysis of A Trial Comparing Safety and Efficacy of Carboplatin and Paclitaxel Plus or Minus Sorafenib (BAY43-9006) in Chemonaive Patients With Stage IIIB-IV Non-Small Cell Lung Cancer (NSCLC): primary endpoint…Phase 3Results postedn = 91NCT00558636
• A Trial Comparing Treatment With Tiotropium Inhalation Capsules to Combivent Inhalation Aerosol in COPD Patients.: Complete Statistical AnalysisIndependent statistical analysis of A Trial Comparing Treatment With Tiotropium Inhalation Capsules to Combivent Inhalation Aerosol in COPD Patients.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 4Results postedn = 349NCT00359788
• A Trial of GC4419 in Patients With Critical Illness Due to COVID-19: Complete Statistical AnalysisIndependent statistical analysis of A Trial of GC4419 in Patients With Critical Illness Due to COVID-19: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 16NCT04555096
• A Trial to Evaluate the Safety and Immunogenicity of ADACEL® Vaccine in Persons 65 Years of Age and Older: Complete Statistical AnalysisIndependent statistical analysis of A Trial to Evaluate the Safety and Immunogenicity of ADACEL® Vaccine in Persons 65 Years of Age and Older: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 4Results postedn = 1,564NCT00457249
• A Trial With Chemotherapy, Immunotherapy, and Radiotherapy for Patients With Newly Diagnosed Stage IV Small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Trial With Chemotherapy, Immunotherapy, and Radiotherapy for Patients With Newly Diagnosed Stage IV Small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 2Results postedn = 6NCT04951115
• AAINTVAPIndependent statistical analysis of Aerosolized Antibiotics in the Treatment of Ventilator Associated Pneumonia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02478710).Phase 4Results postedn = 16NCT02478710
• Abatacept in Treating Adults With Mild Relapsing Wegener’s Granulomatosis: Complete Statistical AnalysisIndependent statistical analysis of Abatacept in Treating Adults With Mild Relapsing Wegener's Granulomatosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00468208).Phase 1/2Results postedn = 20NCT00468208
• ACTIV-6: COVID-19 Study of Repurposed Medications: Complete Statistical AnalysisIndependent statistical analysis of ACTIV-6: COVID-19 Study of Repurposed Medications: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04885530).Phase 3Results postedn = 10,956NCT04885530
• ActiveCOPDIndependent statistical analysis of Active for Life: Chronic Obstructive Pulmonary Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03201198).Phase NAResults postedn = 182NCT03201198
• ACTT-3Independent statistical analysis of ACTT-3, the phase 3 randomized trial of remdesivir plus interferon beta-1a versus remdesivir plus placebo in COVID-19, including time-to-recovery, subgroup hazard ratios, safety, and statistical interpretation.Phase 3Results postedn = 969NCT04492475

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