Respiratory Clinical Trials

Statistical methods in respiratory trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All respiratory trials

865 results

• Design and Usability Testing of a Tailored Intervention About Sleep and Sleep Disorders Among Transportation Workers: Complete Statistical AnalysisIndependent statistical analysis of Design and Usability Testing of a Tailored Intervention About Sleep and Sleep Disorders Among Transportation Workers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase NAResults postedn = 38NCT05039528
• DESTINATIONIndependent statistical analysis of the DESTINATION phase 3 trial of tezepelumab in adults and adolescents with severe, uncontrolled asthma, including trial design, registered endpoints, annualized asthma exacerbation rate results, safety, and statistical…Phase 3Results postedn = 951NCT03706079
• DESTINATIONIndependent statistical analysis of Extension Study to Evaluate the Safety and Tolerability of Tezepelumab in Adults and Adolescents With Severe, Uncontrolled Asthma: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 3Results postedn = 951NCT03706079
• Development of Childhood Anti-Influenza Immunity: Complete Statistical AnalysisIndependent statistical analysis of Development of Childhood Anti-Influenza Immunity: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03673345).Phase 4Results postedn = 125NCT03673345
• Diaphragm Pacing in Individuals With Spinal Cord Injuries: Complete Statistical AnalysisIndependent statistical analysis of Diaphragm Pacing in Individuals With Spinal Cord Injuries: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04179799).Phase NAResults postedn = 6NCT04179799
• Dietary Control Alone Versus Dietary Control Plus Use of Proton Pump Inhibitors to Treat Pediatric Hoarseness: Complete Statistical AnalysisIndependent statistical analysis of Dietary Control Alone Versus Dietary Control Plus Use of Proton Pump Inhibitors to Treat Pediatric Hoarseness: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 4Results postedn = 9NCT00637416
• Dietary Nitrate for Heart Failure: Complete Statistical AnalysisIndependent statistical analysis of Dietary Nitrate for Heart Failure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01682356).Phase 1/2Results postedn = 17NCT01682356
• Digital Interventions to Treat Hazardous Drinking: Complete Statistical AnalysisIndependent statistical analysis of Digital Interventions to Treat Hazardous Drinking: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04890652).Phase NAResults postedn = 33NCT04890652
• Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension: Complete Statistical AnalysisIndependent statistical analysis of Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02981082).Phase 1Results postedn = 6NCT02981082
• Dimethyl Fumarate for Obstructive Sleep Apnea: Complete Statistical AnalysisIndependent statistical analysis of Dimethyl Fumarate for Obstructive Sleep Apnea: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02438137).Phase 2Results postedn = 65NCT02438137
• Disposable Powered Articulating Linear Cutter Stapler in Total-Thoracoscopic Anatomic Lobectomy (Segmentectomy): Complete Statistical AnalysisIndependent statistical analysis of Disposable Powered Articulating Linear Cutter Stapler in Total-Thoracoscopic Anatomic Lobectomy (Segmentectomy): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 164NCT05329402
• Docetaxel & Oxaliplatin in Combination With Bevacizumab as First-Line Treatment in Subjects With Non-Small Cell Lung Cancer (NSCLC): Complete Statistical AnalysisIndependent statistical analysis of Docetaxel & Oxaliplatin in Combination With Bevacizumab as First-Line Treatment in Subjects With Non-Small Cell Lung Cancer (NSCLC): primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 2Results postedn = 53NCT00356122
• Docetaxel With or Without FGFR Inhibitor AZD4547 in Treating Patients With Recurrent Non-Small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of Docetaxel With or Without FGFR Inhibitor AZD4547 in Treating Patients With Recurrent Non-Small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 1/2Results postedn = 2NCT01824901
• Dosage Schedule Study of Pemetrexed Monochemotherapy for Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC): Complete Statistical AnalysisIndependent statistical analysis of Dosage Schedule Study of Pemetrexed Monochemotherapy for Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 19NCT00370292
• Dose Escalation Study MORAb-066 Targeting Tissue Factor (TF)-Expressing Malignancies Including Breast, Pancreatic, Colorectal, NSCLC: Complete Statistical AnalysisIndependent statistical analysis of Dose Escalation Study MORAb-066 Targeting Tissue Factor (TF)-Expressing Malignancies Including Breast, Pancreatic, Colorectal, NSCLC: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 1Results postedn = 27NCT01761240
• Dose Escalation Study of QR-010 in Homozygous ΔF508 Cystic Fibrosis Patients: Complete Statistical AnalysisIndependent statistical analysis of Dose Escalation Study of QR-010 in Homozygous ΔF508 Cystic Fibrosis Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 1/2Results postedn = 70NCT02532764
• Dose Escalation Trial of Intra-Tumoral Injection of NIS Measles Virus in Combination With Atezolizumab: Complete Statistical AnalysisIndependent statistical analysis of Dose Escalation Trial of Intra-Tumoral Injection of NIS Measles Virus in Combination With Atezolizumab: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 1Results postedn = 2NCT02919449
• Dose Finding Study of Fluticasone Furoate Nasal Spray for Uncomplicated Acute Rhinosinusitis: Complete Statistical AnalysisIndependent statistical analysis of Dose Finding Study of Fluticasone Furoate Nasal Spray for Uncomplicated Acute Rhinosinusitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 741NCT01018030
• Dose Ranging Study Evaluating the Efficacy and Safety of GSK2190915 Administered Once Daily: Complete Statistical AnalysisIndependent statistical analysis of Dose Ranging Study Evaluating the Efficacy and Safety of GSK2190915 Administered Once Daily: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 2Results postedn = 700NCT01147744
• DREAMIndependent statistical analysis of the DREAM phase 2 dose-ranging trial of intravenous mepolizumab in severe asthma, explaining the negative binomial regression, exacerbation rate ratios, confidence intervals and serious adverse events by dose.Phase 2Results postedn = 621NCT01000506
• Driving Neuroplasticity With Nerve Stimulation and Modified CIT: Complete Statistical AnalysisIndependent statistical analysis of Driving Neuroplasticity With Nerve Stimulation and Modified CIT: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02587234).Phase 1/2Results postedn = 21NCT02587234
• Drug-Drug Interaction Study of TAK-788 and Midazolam in Participants With Advanced Non-small Cell Lung Cancer (NSCLC): Complete Statistical AnalysisIndependent statistical analysis of Drug-Drug Interaction Study of TAK-788 and Midazolam in Participants With Advanced Non-small Cell Lung Cancer (NSCLC): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 1Results postedn = 26NCT04051827
• Durability of Hypertonic Saline for Enhancing Mucociliary Clearance in Cystic Fibrosis: Complete Statistical AnalysisIndependent statistical analysis of Durability of Hypertonic Saline for Enhancing Mucociliary Clearance in Cystic Fibrosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 1Results postedn = 16NCT01094704
• DW224-III-3Independent statistical analysis of A Study to Evaluate Efficacy and Safety Profile of Zabofloxacin Tablet 400mg and Moxifloxacin Tablet 400mg: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 345NCT01658020
• Dymista Allergen Chamber – Onset of Action Study: Complete Statistical AnalysisIndependent statistical analysis of Dymista Allergen Chamber - Onset of Action Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04652245).Phase 4Results postedn = 216NCT04652245
• DYNAGITOIndependent statistical analysis of DYNAGITO (NCT02296138), a phase 3 trial of tiotropium/olodaterol 5/5 µg versus tiotropium 5 µg for moderate to severe COPD exacerbations: negative binomial rate ratios, 99% confidence intervals, a…Phase 3Results postedn = 7,903NCT02296138
• E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease: Complete Statistical AnalysisIndependent statistical analysis of E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03863509).Phase NAResults postedn = 450NCT03863509
• E-TRaINIndependent statistical analysis of Effectiveness of Interventions to Teach Respiratory Inhaler Technique (E-TRaIN): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01426581).Phase NAResults postedn = 120NCT01426581
• Early Antibiotics After Aspiration in ICU Patients: Complete Statistical AnalysisIndependent statistical analysis of Early Antibiotics After Aspiration in ICU Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05079620).Phase 4Results postedn = 5NCT05079620
• Early Insulin and Development of ARDS: Complete Statistical AnalysisIndependent statistical analysis of Early Insulin and Development of ARDS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00605696).Phase 2Results postedn = 18NCT00605696
• EASI-AS-ODTIndependent statistical analysis of Early Administration of Steroids in the Ambulance Setting: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03962894).Phase 4Results postedn = 834NCT03962894
• eCareIndependent statistical analysis of Developing a Virtual Stress Management Intervention for Spousal/Partnered Caregivers of Solid Tumor Cancer Patients.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase NAResults postedn = 538NCT04739696
• ECLIPSEIndependent statistical analysis of the ECLIPSE clinical trial evaluating longitudinal identification of predictive surrogate endpoints and patient subtypes in chronic obstructive pulmonary disease.n = 2,747NCT00292552
• EDENIndependent statistical analysis of EDEN (NCT00883948), a phase 3 randomized trial comparing minimal trophic feeding with full feeding in people with acute lung injury or acute respiratory distress syndrome.Phase 3n = 1,000NCT00883948
• EDUCATEIndependent statistical analysis of Clinical Trial to Evaluate the Immunogenicity of an Adjuvanted Influenza Vaccine Among HCP: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 3Results postedn = 192NCT06054269
• Effect of Brovana and Tiotropium in Chronic Obstructive Pulmonary Disease (COPD): Complete Statistical AnalysisIndependent statistical analysis of Effect of Brovana and Tiotropium in Chronic Obstructive Pulmonary Disease (COPD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 4Results postedn = 20NCT00773786
• Effect of Dalcetrapib in Patients With Confirmed Mild to Moderate COVID-19: Complete Statistical AnalysisIndependent statistical analysis of Effect of Dalcetrapib in Patients With Confirmed Mild to Moderate COVID-19: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 2Results postedn = 227NCT04676867
• Effect of Gefapixant (MK-7264/AF-219) on Cough Reflex Sensitivity in Healthy and Chronic Cough Participants (MK-7264-014): Complete Statistical AnalysisIndependent statistical analysis of Effect of Gefapixant (MK-7264/AF-219) on Cough Reflex Sensitivity in Healthy and Chronic Cough Participants (MK-7264-014): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 2Results postedn = 36NCT02476890
• Effect of Hypertonic Saline on Mucus Clearance in Children Ages 5-12 With Cystic Fibrosis: Complete Statistical AnalysisIndependent statistical analysis of Effect of Hypertonic Saline on Mucus Clearance in Children Ages 5-12 With Cystic Fibrosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase NAResults postedn = 23NCT01031706
• Effect of Indacaterol on Inspiratory Capacity (IC): Complete Statistical AnalysisIndependent statistical analysis of Effect of Indacaterol on Inspiratory Capacity (IC): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01012765).Phase 3Results postedn = 173NCT01012765
• Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH: Complete Statistical AnalysisIndependent statistical analysis of Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 10NCT02734953
• Effect of Liraglutide in Obese Subjects With Moderate or Severe Obstructive Sleep Apnoea: SCALE™ – Sleep Apnoea: Complete Statistical AnalysisIndependent statistical analysis of Effect of Liraglutide in Obese Subjects With Moderate or Severe Obstructive Sleep Apnoea: SCALE™ - Sleep Apnoea: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 3Results postedn = 359NCT01557166
• Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic Bronchitis: Complete Statistical AnalysisIndependent statistical analysis of Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic Bronchitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 4Results postedn = 31NCT02416102
• Effect of Macrolide Antibiotics on Airway Inflammation in People With Chronic Obstructive Pulmonary Disease (COPD): Complete Statistical AnalysisIndependent statistical analysis of Effect of Macrolide Antibiotics on Airway Inflammation in People With Chronic Obstructive Pulmonary Disease (COPD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase NAResults postedn = 53NCT00549445
• Effect of Symbicort ® on GR in Sputum in COPD: Complete Statistical AnalysisIndependent statistical analysis of Effect of Symbicort ® on GR in Sputum in COPD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01787097).Phase 4Results postedn = 31NCT01787097
• Effect of Tranexamic Acid on Postoperative Bleeding Following Sinus and Nasal Surgery: Complete Statistical AnalysisIndependent statistical analysis of Effect of Tranexamic Acid on Postoperative Bleeding Following Sinus and Nasal Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 4Results postedn = 40NCT04754230
• Effect of Veramyst on the Nasal and Ocular Symptoms of the Early Reaction to Nasal Challenge With Allergen: Complete Statistical AnalysisIndependent statistical analysis of Effect of Veramyst on the Nasal and Ocular Symptoms of the Early Reaction to Nasal Challenge With Allergen: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 4Results postedn = 15NCT00791973
• Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients: Complete Statistical AnalysisIndependent statistical analysis of Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 3Results postedn = 295NCT01533922
• Effectiveness of a Computer Application in Improving Pulmonary Artery Catheter Waveform Interpretation: Complete Statistical AnalysisIndependent statistical analysis of Effectiveness of a Computer Application in Improving Pulmonary Artery Catheter Waveform Interpretation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase NAResults postedn = 55NCT00138073
• Effectiveness of Chinese Herbal Therapy for Asthma: Complete Statistical AnalysisIndependent statistical analysis of Effectiveness of Chinese Herbal Therapy for Asthma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00712296).Phase 1/2Results postedn = 66NCT00712296

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