Topic: Biological Plausibility and Parameter Uncertainty

Worked Plausibility Audit for Tissue Distribution

Worked Uncertainty Analysis for Hepatic Exposure

Uncertainty in Reference Physiology Across Populations

Separating Parameter Uncertainty from Output Variability

Sampling Parameter Sets for PBPK Uncertainty Analysis

Representing Correlated Parameter Uncertainty

Propagating Uncertainty Under Parameter Dependence

Propagating Parameter Uncertainty Through a Tissue Model

Plausibility Audits for PBPK Parameter Sets

Plausibility Checks for Physicochemical Parameter Combinations