Topic: Hepatic Uptake and Efflux Transporters

Worked Example of Extended Clearance Calculation

Unbound Intracellular Concentrations in Transport Models

Using Membrane Vesicles to Measure Transporter Activity

Using Sandwich-Cultured Hepatocytes for Biliary Efflux

Translating Hepatic Transporter Activity Across Species

Testing Extended Clearance Models Against In Vivo Evidence

Sinusoidal and Canalicular Transporter Topology

Scaling Transporter Activity From In Vitro to Liver

Representing Hepatic Zonation in Transporter Models

Reading Plasma and Biliary Data for Transporter Mechanisms