Topic: Hepatic Uptake and Efflux Transporters

Recognizing Uptake-Limited and Elimination-Limited Clearance

Partitioning Intracellular Loss Between Bile and Blood

Modeling Hepatocyte Efflux Pathways

Michaelis-Menten Models of Hepatic Uptake

Kinetic Parameters for Hepatic Transporters

Implementing Transporter Fluxes in a Hepatic ODE Model

Estimating Uptake Clearance From Hepatocyte Assays

Embedding Transporter Clearance in the Well-Stirred Liver

Diagnosing Uptake and Metabolism Parameter Identifiability

Deriving the Hepatocyte Intracellular Mass Balance