Topic: Pediatric Ontogeny and Scaling

Prematurity and Gestational-Age Effects on Drug-Metabolizing Capacity

Propagating Ontogeny Uncertainty to Pediatric Exposure Predictions

Integrating Age-Dependent Hepatic Intrinsic Clearance

Gestational, Postnatal, and Postmenstrual Age in PBPK Models

Fitting Maturation Curves to Sparse Age-Stratified Data

Estimating Between-Child Variability in Maturation

Developmental Plasma Binding and Blood-to-Plasma Ratios

Developmental Profiles of CYP3A, CYP2D6, and CYP2C Enzymes

Developmental Renal Filtration and Secretory Transport

Diagnosing Confounding Between Age, Size, and Maturation