QSP Models of Hemodynamics
Learn how quantitative systems pharmacology models represent hemodynamics by connecting cardiac output, vascular resistance, blood pressure, blood volume, and drug effects within mechanistic cardiovascular models.
QSP Models of Glucose-Insulin Regulation
Learn how quantitative systems pharmacology models describe glucose-insulin regulation, including glucose production and uptake, insulin secretion, insulin action, feedback, and how mechanistic QSP models connect physiology to pharmacologic interventions.
QSP Models of Diabetes Therapies
An introduction to quantitative systems pharmacology models of diabetes therapies, including glucose-insulin regulation, insulin resistance, beta-cell function, drug mechanisms, biomarkers, combination therapy, and model-based prediction.
QSP Models of Cytokine Signaling
Learn how quantitative systems pharmacology models represent cytokine production, receptor binding, JAK-STAT signaling, feedback, immune-cell communication, pharmacologic modulation, and cytokine-driven disease biology.
QSP Models of Combination Therapy
Learn how quantitative systems pharmacology models represent combination therapies, including target interactions, synergy, competition, pathway modulation, combination mechanisms, model construction, calibration, and simulation.
QSP Models of Cancer Signaling Pathways
Learn how quantitative systems pharmacology models represent cancer signaling pathways, connect molecular mechanisms to drug exposure and tumor response, and support mechanistic interpretation, simulation, and therapeutic decision-making.
QSP Models of CAR-T Cell Therapy
An introduction to quantitative systems pharmacology models of CAR-T cell therapy, including CAR-T expansion, trafficking, target engagement, tumor killing, cytokine dynamics, persistence, and sources of variability.
QSP Models of Bispecific Antibodies
Learn how quantitative systems pharmacology models describe bispecific antibodies, including dual-target binding, target engagement, ternary complex formation, immune-cell activation, tumor killing, cytokine release, PK, PD, and model-based dose and regimen prediction.
QSP Models of Autoimmune Disease
An introduction to quantitative systems pharmacology models of autoimmune disease, including immune-cell dynamics, cytokine signaling, target engagement, disease mechanisms, treatment response, biomarkers, and mechanistic simulation.
QSP Models of Antiviral Drug Action
Learn how quantitative systems pharmacology models describe antiviral drug action by connecting pharmacokinetics, viral dynamics, target cells, infected cells, immune responses, and mechanisms of antiviral therapy.