Topic: Sensitivity Analysis and Parameter Reduction

Morris Screening for PBPK Parameters

Local Sensitivity as an Output Derivative

Lumping Parameters with Similar Effects

Interpreting Local Sensitivity Rankings

Grouped Sensitivity for Physiological Processes

Global Sensitivity with Correlated Parameters

Finite-Difference Sensitivity Calculations

Fixing Low-Influence Parameters

Forward Sensitivity Equations for PBPK ODEs

Dimensionless Sensitivity Coefficients