Topic: Target Trial Emulation

Worked Emulation of a Treatment-Initiation Trial

Worked Emulation of Sustained Treatment Strategies

The Target Trial Protocol as a Causal Question

Treatment Assignment and Its Observational Analog

Treatment Strategies as Operational Rules

Selection Bias from Eligibility and Treatment Classification

Sensitivity Analysis for Protocol Choices

Sequential Trial Emulation with Repeated Eligibility

Protocol Audit for Immortal Time and Selection Bias

Per-Protocol Effects Under Sustained Strategies