Topic: Target Trial Emulation

Outcome Definitions and Ascertainment

Outcome Measurement Under Unequal Observation

New-User Designs for Treatment Initiation

Intention-to-Treat Analogs in Observational Data

Interpreting Differences from a Randomized Trial

Grace Periods for Treatment Initiation

Handling Treatment Changes After Assignment

Immortal Time Bias from Misaligned Treatment Definitions

Feasibility Checks Before Emulation

Follow-Up Windows and Trial Endpoints