Trials that use: Interim analysis / alpha spending
New to this method? Read the tutorial →
3,770 results
- A Study in Healthy Men to Test the Effects of Different Doses of BI 1467335 on MAO-B Activity in the Brain.: Complete Statistical AnalysisIndependent statistical analysis of A Study in Healthy Men to Test the Effects of Different Doses of BI 1467335 on MAO-B Activity in the Brain.: primary endpoint results, effect estimate with confidence…
- A Study in Healthy Men to Test Whether Food Affects the Amount of BI 894416 in the Blood: Complete Statistical AnalysisIndependent statistical analysis of A Study in Healthy Men to Test Whether Food Affects the Amount of BI 894416 in the Blood: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study in Healthy People to Test Whether BI 730357 Influences the Amount of Caffeine, Warfarin, Omeprazole, and Midazolam in the Blood: Complete Statistical AnalysisIndependent statistical analysis of A Study in Healthy People to Test Whether BI 730357 Influences the Amount of Caffeine, Warfarin, Omeprazole, and Midazolam in the Blood: primary endpoint results, effect estimate with…
- A Study in Healthy Women to Test Whether BI 1358894 Influences the Amount of a Contraceptive in the Blood: Complete Statistical AnalysisIndependent statistical analysis of A Study in Healthy Women to Test Whether BI 1358894 Influences the Amount of a Contraceptive in the Blood: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study In Japanese Healthy Male Volunteers To Investigate The Safety, Tolerability And Pharmacokinetics Of PF-02341066: Complete Statistical AnalysisIndependent statistical analysis of A Study In Japanese Healthy Male Volunteers To Investigate The Safety, Tolerability And Pharmacokinetics Of PF-02341066: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study in Participants With Acute Major Bleeding to Evaluate the Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Direct and Indirect Oral Anticoagulants (Extension Study): Complete Statistical AnalysisIndependent statistical analysis of A Study in Participants With Acute Major Bleeding to Evaluate the Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Direct and Indirect Oral Anticoagulants (Extension Study):…
- A Study in Participants With Diabetic Kidney Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study in Participants With Diabetic Kidney Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01113801).
- A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN): Complete Statistical AnalysisIndependent statistical analysis of A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study In Patients With Neuropathic Pain From Post-Herpetic Neuralgia (PHN): Complete Statistical AnalysisIndependent statistical analysis of A Study In Patients With Neuropathic Pain From Post-Herpetic Neuralgia (PHN): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of 2 Different Formulations of Insulin Lispro in Healthy Participants: Complete Statistical AnalysisIndependent statistical analysis of A Study of 2 Different Formulations of Insulin Lispro in Healthy Participants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of a Mastoid Device in Subjects With Ménière’s Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study of a Mastoid Device in Subjects With Ménière's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of Abemaciclib (LY2835219) Alone or in Combination With Other Agents in Participants With Previously Treated Pancreatic Ductal Adenocarcinoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Abemaciclib (LY2835219) Alone or in Combination With Other Agents in Participants With Previously Treated Pancreatic Ductal Adenocarcinoma: primary endpoint results, effect estimate with confidence interval,…
- A Study of Abemaciclib in Indian Women With Advanced Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Abemaciclib in Indian Women With Advanced Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of Abemaciclib in Participants With Cancer That is Advanced or Has Spread to Another Part(s) of the Body: Complete Statistical AnalysisIndependent statistical analysis of A Study of Abemaciclib in Participants With Cancer That is Advanced or Has Spread to Another Part(s) of the Body: primary endpoint results, effect estimate with confidence interval,…
- A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG: Complete Statistical AnalysisIndependent statistical analysis of A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of Adalimumab After Dose Escalation in Japanese Subjects With Crohn’s Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study of Adalimumab After Dose Escalation in Japanese Subjects With Crohn's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of Adalimumab in Japanese Subjects With Moderately to Severely Active Ulcerative Colitis: Complete Statistical AnalysisIndependent statistical analysis of A Study of Adalimumab in Japanese Subjects With Moderately to Severely Active Ulcerative Colitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of Adjuvant Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab for Resected High-Risk Melanoma in Participants With High-Risk Stage II-IV Melanoma (MK-7684A-010/KEYVIBE-010): Complete Statistical AnalysisIndependent statistical analysis of A Study of Adjuvant Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab for Resected High-Risk Melanoma in Participants With High-Risk Stage II-IV Melanoma (MK-7684A-010/KEYVIBE-010): primary endpoint results, effect estimate with confidence interval,…
- A Study of AG-348 in Adult Participants With Pyruvate Kinase (PK) Deficiency: Complete Statistical AnalysisIndependent statistical analysis of A Study of AG-348 in Adult Participants With Pyruvate Kinase (PK) Deficiency: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of AGN-195263 for the Treatment of Meibomian Gland Dysfunction: Complete Statistical AnalysisIndependent statistical analysis of A Study of AGN-195263 for the Treatment of Meibomian Gland Dysfunction: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of AGS-16C3F vs. Axitinib in Metastatic Renal Cell Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of AGS-16C3F vs. Axitinib in Metastatic Renal Cell Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of ALXN1840 (Non-coated) Administered With And Without Omeprazole In Healthy Adults: Complete Statistical AnalysisIndependent statistical analysis of A Study of ALXN1840 (Non-coated) Administered With And Without Omeprazole In Healthy Adults: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of an Investigational Drug Sitagliptin for Type 2 Diabetes Mellitus (0431-044): Complete Statistical AnalysisIndependent statistical analysis of A Study of an Investigational Drug Sitagliptin for Type 2 Diabetes Mellitus (0431-044): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of an Investigational Regimen Combining FDA Approved HIV Drugs in HIV-Infected Subjects: Complete Statistical AnalysisIndependent statistical analysis of A Study of an Investigational Regimen Combining FDA Approved HIV Drugs in HIV-Infected Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of an Investigational V212/Heat-Treated Varicella-Zoster Virus (VZV) Vaccine in Immunocompromised Adults (V212-002): Complete Statistical AnalysisIndependent statistical analysis of A Study of an Investigational V212/Heat-Treated Varicella-Zoster Virus (VZV) Vaccine in Immunocompromised Adults (V212-002): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19: Complete Statistical AnalysisIndependent statistical analysis of A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of Aripiprazole Lauroxil (Also Known as ARISTADA TM) in Subjects With Schizophrenia: Complete Statistical AnalysisIndependent statistical analysis of A Study of Aripiprazole Lauroxil (Also Known as ARISTADA TM) in Subjects With Schizophrenia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of ASP2215 (Gilteritinib), Administered as Maintenance Therapy Following Induction/Consolidation Therapy for Subjects With FMS-like Tyrosine Kinase 3 (FLT3/ITD) Acute Myeloid Leukemia (AML) in First Complete Remission: Complete Statistical AnalysisIndependent statistical analysis of A Study of ASP2215 (Gilteritinib), Administered as Maintenance Therapy Following Induction/Consolidation Therapy for Subjects With FMS-like Tyrosine Kinase 3 (FLT3/ITD) Acute Myeloid Leukemia (AML) in First Complete Remission:…
- A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation: Complete Statistical AnalysisIndependent statistical analysis of A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation: primary endpoint results, effect estimate…
- A Study of Aspirin and Simvastatin in Pulmonary Arterial Hypertension: Complete Statistical AnalysisIndependent statistical analysis of A Study of Aspirin and Simvastatin in Pulmonary Arterial Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00384865).
- A Study of Atezolizumab in Combination With Carboplatin or Cisplatin + Pemetrexed Compared With Carboplatin or Cisplatin + Pemetrexed in Participants Who Are Chemotherapy-Naive and Have Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower 132): Complete Statistical AnalysisIndependent statistical analysis of A Study of Atezolizumab in Combination With Carboplatin or Cisplatin + Pemetrexed Compared With Carboplatin or Cisplatin + Pemetrexed in Participants Who Are Chemotherapy-Naive and Have Stage IV…
- A Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer (Cohort 1): Complete Statistical AnalysisIndependent statistical analysis of A Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer (Cohort 1): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of Auxora in Patients With Critical COVID-19 Pneumonia: Complete Statistical AnalysisIndependent statistical analysis of A Study of Auxora in Patients With Critical COVID-19 Pneumonia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04661540).
- A Study of Avastin (Bevacizumab) Added to a Chemotherapeutic Regimen in Patients With Metastatic Pancreatic Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Avastin (Bevacizumab) Added to a Chemotherapeutic Regimen in Patients With Metastatic Pancreatic Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of Avastin (Bevacizumab) And Fotemustine in Patients With Recurrent Glioblastoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Avastin (Bevacizumab) And Fotemustine in Patients With Recurrent Glioblastoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of Avastin (Bevacizumab) and Xeloda (Capecitabine) in Patients With Advanced or Metastatic Liver Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Avastin (Bevacizumab) and Xeloda (Capecitabine) in Patients With Advanced or Metastatic Liver Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Breast Cancer Progressing After First-Line Therapy With Avastin and Chemotherapy (TANIA): Complete Statistical AnalysisIndependent statistical analysis of A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Breast Cancer Progressing After First-Line Therapy With Avastin and Chemotherapy (TANIA): primary endpoint results, effect estimate…
- A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF): Complete Statistical AnalysisIndependent statistical analysis of A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF): primary endpoint results, effect estimate with confidence interval,…
- A Study of Baricitinib (LY3009104) in Adult and Pediatric Japanese Participants With NNS/CANDLE, SAVI, and AGS: Complete Statistical AnalysisIndependent statistical analysis of A Study of Baricitinib (LY3009104) in Adult and Pediatric Japanese Participants With NNS/CANDLE, SAVI, and AGS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of BBI503 in Asymptomatic Recurrent Ovarian Cancer Patients With CA-125 Elevation: Complete Statistical AnalysisIndependent statistical analysis of A Study of BBI503 in Asymptomatic Recurrent Ovarian Cancer Patients With CA-125 Elevation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of BBI608 Administered With Paclitaxel in Adult Patients With Advanced Malignancies: Complete Statistical AnalysisIndependent statistical analysis of A Study of BBI608 Administered With Paclitaxel in Adult Patients With Advanced Malignancies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural Mesothelioma: Complete Statistical AnalysisIndependent statistical analysis of A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural Mesothelioma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study of Belimumab in the Prevention of Kidney Transplant Rejection: Complete Statistical AnalysisIndependent statistical analysis of A Study of Belimumab in the Prevention of Kidney Transplant Rejection: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of Bempegaldesleukin (NKTR-214: BEMPEG) in Combination With Nivolumab Compared With the Investigator’s Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib or Cabozantinib Monotherapy) for Advanced Metastatic Renal Cell Carcinoma (RCC): Complete Statistical AnalysisIndependent statistical analysis of A Study of Bempegaldesleukin (NKTR-214: BEMPEG) in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib or Cabozantinib Monotherapy) for…
- A Study of Bevacizumab (Avastin) in Combination With Dacarbazine in Participants With Unresectable/Metastatic Melanoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Bevacizumab (Avastin) in Combination With Dacarbazine in Participants With Unresectable/Metastatic Melanoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of BGB324 (Bemcentinib) in Combination With Erlotinib in Patients With Non-Small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of BGB324 (Bemcentinib) in Combination With Erlotinib in Patients With Non-Small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of BMS-863233 in Patients With Advanced and/or Metastatic Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of A Study of BMS-863233 in Patients With Advanced and/or Metastatic Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of Bonviva (Ibandronate) and Alendronate on Renal Function in Postmenopausal Women With Osteoporosis at High Risk for Renal Disease.: Complete Statistical AnalysisIndependent statistical analysis of A Study of Bonviva (Ibandronate) and Alendronate on Renal Function in Postmenopausal Women With Osteoporosis at High Risk for Renal Disease.: primary endpoint results, effect estimate with confidence…
- A Study of Bonviva (Ibandronate) Once Monthly in Post-Menopausal Women With Osteopenia: Complete Statistical AnalysisIndependent statistical analysis of A Study of Bonviva (Ibandronate) Once Monthly in Post-Menopausal Women With Osteopenia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…