Statistical methods in critical care & injury trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
Logistic regression
Odds ratio
ANCOVA
Hazard ratio
t-test
Fisher exact test
Non-inferiority trial design
Wilcoxon / Mann-Whitney test
All critical care & injury trials
184 results
- A Comparison of Propofol Versus Midazolam to Sedate Critically Brain Injury; Measurement of Cytokine Response and Assessment of Function: Complete Statistical AnalysisIndependent statistical analysis of A Comparison of Propofol Versus Midazolam to Sedate Critically Brain Injury; Measurement of Cytokine Response and Assessment of Function: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Comparison of Ropivacaine Alone Versus Combination of Dexamethasone and Clonidine for Block: Complete Statistical AnalysisIndependent statistical analysis of A Comparison of Ropivacaine Alone Versus Combination of Dexamethasone and Clonidine for Block: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Foot/Ankle: Complete Statistical AnalysisIndependent statistical analysis of A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Foot/Ankle: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Phase 2 Extension Study To Enroll Subjects Who Were Enrolled In B5301001 Study: Complete Statistical AnalysisIndependent statistical analysis of A Phase 2 Extension Study To Enroll Subjects Who Were Enrolled In B5301001 Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Pilot Trial to Determine the Effective N-acetylcysteine Dose for Opioid Reduction for Spine Surgery.: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Trial to Determine the Effective N-acetylcysteine Dose for Opioid Reduction for Spine Surgery.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1: Complete Statistical AnalysisIndependent statistical analysis of A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1: primary endpoint results, effect…
- A Safety Study of of AG-920 Sterile Topical Ophthalmic Solution: Complete Statistical AnalysisIndependent statistical analysis of A Safety Study of of AG-920 Sterile Topical Ophthalmic Solution: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05501860).
- A Study of Fisetin to Treat Carpal Tunnel Syndrome: Complete Statistical AnalysisIndependent statistical analysis of A Study of Fisetin to Treat Carpal Tunnel Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05416515).
- A Study of TAK-954 to Treat Gastrointestinal Dysfunction in Adults After Surgery: Complete Statistical AnalysisIndependent statistical analysis of A Study of TAK-954 to Treat Gastrointestinal Dysfunction in Adults After Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study to Compare the Safety and Efficacy of a New Eye Drop Formulation With REFRESH PLUS® in Participants Following LASIK Refractive Surgery: Complete Statistical AnalysisIndependent statistical analysis of A Study to Compare the Safety and Efficacy of a New Eye Drop Formulation With REFRESH PLUS® in Participants Following LASIK Refractive Surgery: primary endpoint results, effect estimate…
- A Telerehabilitation Program for SCI: Complete Statistical AnalysisIndependent statistical analysis of A Telerehabilitation Program for SCI: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04977037).
- AC105Independent statistical analysis of AC105 in Patients With Acute Traumatic Spinal Cord Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01750684).
- Acupuncture ACL (Anterior Cruciate Ligament): Complete Statistical AnalysisIndependent statistical analysis of Acupuncture ACL (Anterior Cruciate Ligament): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03711734).
- Acute Neurobehavioral Program for Improving Functional Status After TBI: Complete Statistical AnalysisIndependent statistical analysis of Acute Neurobehavioral Program for Improving Functional Status After TBI: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01166386).
- AHAvsSIMIndependent statistical analysis of A Trial to Compare American Heart Association (AHA) and Simple (SIM)Method to Give Adenosine to Treat Supra-ventricular Tachycardia (SVT): primary endpoint results, effect estimate with confidence interval, sample-size…
- ALCIndependent statistical analysis of Acetyl-L-Carnitine in the Treatment of Septic Shock: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00592488).
- Algorithm for Predicting the Unfavorable Course of Sepsis in Children: Complete Statistical AnalysisIndependent statistical analysis of Algorithm for Predicting the Unfavorable Course of Sepsis in Children: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05908162).
- Alkaline Water in Reducing Skin Toxicity in Women With Breast Cancer Undergoing Radiation Therapy: Complete Statistical AnalysisIndependent statistical analysis of Alkaline Water in Reducing Skin Toxicity in Women With Breast Cancer Undergoing Radiation Therapy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain: Complete Statistical AnalysisIndependent statistical analysis of An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- ANDROMEDA-SHOCKIndependent statistical analysis of the ANDROMEDA-SHOCK randomized trial comparing peripheral perfusion versus lactate targeted fluid resuscitation in septic shock, including trial design, endpoints, statistical methodology, and interpretation.
- Anidulafungin In Treatment Of Candidemia In Asian Subjects: Complete Statistical AnalysisIndependent statistical analysis of Anidulafungin In Treatment Of Candidemia In Asian Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00537329).
- Anthropometric and US-Guided Difficult Intubation Prediction With ML Models: Complete Statistical AnalysisIndependent statistical analysis of Anthropometric and US-Guided Difficult Intubation Prediction With ML Models: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06904586).
- Approach to Sexuality From Occupational Therapy in People With Acquired Brain Injury in Subacute Stage: Complete Statistical AnalysisIndependent statistical analysis of Approach to Sexuality From Occupational Therapy in People With Acquired Brain Injury in Subacute Stage: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Aprepitant for PONV Prophylaxis in Outpatient Plastic Surgery: Complete Statistical AnalysisIndependent statistical analysis of Aprepitant for PONV Prophylaxis in Outpatient Plastic Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00659945).
- ARISEIndependent statistical analysis of the ARISE phase 3 trial evaluating Early Goal Directed Therapy in severe sepsis, including trial design, endpoints, planned analysis, statistical methodology, and interpretation.
- Aspirin and Enoxaparin for VTE in Trauma: Complete Statistical AnalysisIndependent statistical analysis of Aspirin and Enoxaparin for VTE in Trauma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02396732).
- Assessing Neuroinflammation in GWI Using MRS: Complete Statistical AnalysisIndependent statistical analysis of Assessing Neuroinflammation in GWI Using MRS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04638998).
- Assessment of Dystussia in Traumatic Brain Injury: Complete Statistical AnalysisIndependent statistical analysis of Assessment of Dystussia in Traumatic Brain Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02240329).
- ATNIndependent statistical analysis of Acute Renal Failure Trial Network (ATN) Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00076219).
- Augment® Bone Graft (Formerly GEM OS™1 Bone Graft) Compared to Autologous Bone Graft in Foot and Ankle Fusions: Complete Statistical AnalysisIndependent statistical analysis of Augment® Bone Graft (Formerly GEM OS™1 Bone Graft) Compared to Autologous Bone Graft in Foot and Ankle Fusions: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Avenir Müller Hip Stem Post Market Surveillance Study: Complete Statistical AnalysisIndependent statistical analysis of Avenir Müller Hip Stem Post Market Surveillance Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04079127).
- BASILICAIndependent statistical analysis of the BASILICA prospective investigation in native and valve-in-valve aortic valve failure, including trial design, endpoints, statistical methodology, safety, limitations, and interpretation.
- BEST (Burn Center Evaluation of Standard Therapies) Ventilator Mode Study-: Complete Statistical AnalysisIndependent statistical analysis of BEST (Burn Center Evaluation of Standard Therapies) Ventilator Mode Study-: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00351741).
- BFFIndependent statistical analysis of Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03496545).
- Biomechanical Validation of the Transfer Assessment Instrument (TAI): Complete Statistical AnalysisIndependent statistical analysis of Biomechanical Validation of the Transfer Assessment Instrument (TAI): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01183546).
- Botox + FESIndependent statistical analysis of Efficacy of Functional Electrical Stimulation (FES) in Persons Receiving Botulinum Neurotoxin for Upper Extremity Spasticity: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Botulinum Toxin as a Novel Treatment for Prevention of Post-Traumatic Elbow Stiffness: Complete Statistical AnalysisIndependent statistical analysis of Botulinum Toxin as a Novel Treatment for Prevention of Post-Traumatic Elbow Stiffness: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Brain Training to Enhance Frontal Lobe Reasoning: Complete Statistical AnalysisIndependent statistical analysis of Brain Training to Enhance Frontal Lobe Reasoning: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01552473).
- Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis: Complete Statistical AnalysisIndependent statistical analysis of Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Bundling and Unbundling the Laparoscopic Electrosurgery Cord With the Camera Cord: Complete Statistical AnalysisIndependent statistical analysis of Bundling and Unbundling the Laparoscopic Electrosurgery Cord With the Camera Cord: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- BWSP3Independent statistical analysis of Black Widow Spider Antivenin for Patients With Systemic Latrodectism: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00657540).
- Calibration and Validation of Masimo’s O3 Regional Oximetry Device in Neonates, Infants and Children: Complete Statistical AnalysisIndependent statistical analysis of Calibration and Validation of Masimo's O3 Regional Oximetry Device in Neonates, Infants and Children: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Can Adequacy of Anesthesia Depth and Quality of Recovery be Influenced by the Level of Neuromuscular Blockade?: Complete Statistical AnalysisIndependent statistical analysis of Can Adequacy of Anesthesia Depth and Quality of Recovery be Influenced by the Level of Neuromuscular Blockade?: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- CAN-COVIDIndependent statistical analysis of CAN-COVID, a randomized phase 3 study of canakinumab versus placebo for cytokine release syndrome in participants with COVID-19-induced pneumonia, including its primary binary endpoint, logistic regression, odds ratio,…
- CDP-Choline and Working Memory After TBI: A Neuroimaging Study: Complete Statistical AnalysisIndependent statistical analysis of CDP-Choline and Working Memory After TBI: A Neuroimaging Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00727246).
- CENSERIndependent statistical analysis of CENSER (NCT01945983), a randomized trial evaluating early norepinephrine in septic shock resuscitation, including design, endpoints, planned analysis, and statistical interpretation.
- CEUS For Intraoperative Spinal Cord Injury: Complete Statistical AnalysisIndependent statistical analysis of CEUS For Intraoperative Spinal Cord Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05530798).
- Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia: Complete Statistical AnalysisIndependent statistical analysis of Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Clinical Evaluation of a Dental Glass Ceramic: Complete Statistical AnalysisIndependent statistical analysis of Clinical Evaluation of a Dental Glass Ceramic: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04933123).
- Clinical Outcomes Mandible: Buffered 1% vs. Non-Buffered 1% Lidocaine: Complete Statistical AnalysisIndependent statistical analysis of Clinical Outcomes Mandible: Buffered 1% vs. Non-Buffered 1% Lidocaine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03127943).