Statistical methods in gastroenterology & hepatology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
Cochran-Mantel-Haenszel test
Risk difference
ANCOVA
Non-inferiority trial design
Multiple imputation / missing data
Odds ratio
Fisher exact test
Mixed-effects model
All gastroenterology & hepatology trials
455 results
- A Study of Avastin (Bevacizumab) Plus Xeloda (Capecitabine) in Patients With Locally Advanced Rectal Cancer.: Complete Statistical AnalysisIndependent statistical analysis of A Study of Avastin (Bevacizumab) Plus Xeloda (Capecitabine) in Patients With Locally Advanced Rectal Cancer.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study of Capecitabine [Xeloda] in Combination With Trastuzumab [Herceptin] and Oxaliplatine in Patients With Resectable Gastric Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Capecitabine [Xeloda] in Combination With Trastuzumab [Herceptin] and Oxaliplatine in Patients With Resectable Gastric Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study of CellCept (Mycophenolate Mofetil) in Combination Therapy in Liver Transplant Patients.: Complete Statistical AnalysisIndependent statistical analysis of A Study of CellCept (Mycophenolate Mofetil) in Combination Therapy in Liver Transplant Patients.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007): Complete Statistical AnalysisIndependent statistical analysis of A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007): primary endpoint results, effect estimate with confidence…
- A Study of Combination of Gemcitabine, Oxaliplatin (GEMOX)-Sorafenib in Patients With Advanced Biliary Tract Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Combination of Gemcitabine, Oxaliplatin (GEMOX)-Sorafenib in Patients With Advanced Biliary Tract Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study of Combination or Sequential Treatment With PEGASYS (Peginterferon Alfa-2a) and Entecavir in Patients With HBeAg Positive Chronic Hepatitis B: Complete Statistical AnalysisIndependent statistical analysis of A Study of Combination or Sequential Treatment With PEGASYS (Peginterferon Alfa-2a) and Entecavir in Patients With HBeAg Positive Chronic Hepatitis B: primary endpoint results, effect estimate with confidence…
- A Study of Creon (Pancrelipase) in Resected and Non-resected Pancreatic Cancer Participants With Exocrine Pancreatic Insufficiency (EPI): Complete Statistical AnalysisIndependent statistical analysis of A Study of Creon (Pancrelipase) in Resected and Non-resected Pancreatic Cancer Participants With Exocrine Pancreatic Insufficiency (EPI): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study of Daclatasvir and Sofosbuvir With Ribavirin in Subjects With Cirrhosis and Genotype 3 Hepatitis C Infection: Complete Statistical AnalysisIndependent statistical analysis of A Study of Daclatasvir and Sofosbuvir With Ribavirin in Subjects With Cirrhosis and Genotype 3 Hepatitis C Infection: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study of Darvadstrocel for Treating Complex Perianal Fistulas in Children and Teenagers With Crohn’s Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study of Darvadstrocel for Treating Complex Perianal Fistulas in Children and Teenagers With Crohn's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of DCC-2618 (Ripretinib) In Patients With With Advanced Gastrointestinal Stromal Tumors (GIST): Complete Statistical AnalysisIndependent statistical analysis of A Study of DCC-2618 (Ripretinib) In Patients With With Advanced Gastrointestinal Stromal Tumors (GIST): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of Dexlansoprazole Modified Release Formulation to Treat Night Heartburn: Complete Statistical AnalysisIndependent statistical analysis of A Study of Dexlansoprazole Modified Release Formulation to Treat Night Heartburn: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis: Complete Statistical AnalysisIndependent statistical analysis of A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis: primary endpoint results, effect estimate with confidence interval,…
- A Study of IMC-1121B (Ramucirumab) in Colorectal Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of IMC-1121B (Ramucirumab) in Colorectal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00862784).
- A Study of Intravenous Vedolizumab Administered Every 4 Weeks in Japanese Participants With Moderate to Severe Ulcerative Colitis or Crohn’s Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study of Intravenous Vedolizumab Administered Every 4 Weeks in Japanese Participants With Moderate to Severe Ulcerative Colitis or Crohn's Disease: primary endpoint results, effect estimate with confidence…
- A Study of Irinotecan, Levofolinate, and 5-Fluorouracil (FOLFIRI) Plus Ramucirumab (IMC-1121B): Complete Statistical AnalysisIndependent statistical analysis of A Study of Irinotecan, Levofolinate, and 5-Fluorouracil (FOLFIRI) Plus Ramucirumab (IMC-1121B): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus: Complete Statistical AnalysisIndependent statistical analysis of A Study of Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus: primary endpoint results, effect estimate…
- A Study of Nab-Paclitaxel and Gemcitabine With or Without Olaratumab (LY3012207) in Participants With Metastatic Pancreatic Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Nab-Paclitaxel and Gemcitabine With or Without Olaratumab (LY3012207) in Participants With Metastatic Pancreatic Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study of Nanrilkefusp Alfa (SOT101) in Combination With Cetuximab to Evaluate the Efficacy and Safety in Patients With Colorectal Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Nanrilkefusp Alfa (SOT101) in Combination With Cetuximab to Evaluate the Efficacy and Safety in Patients With Colorectal Cancer: primary endpoint results, effect estimate with confidence…
- A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Hepatitis Be Antigen (HBeAg) Positive Chronic Hepatitis B (CHB).: Complete Statistical AnalysisIndependent statistical analysis of A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Hepatitis Be Antigen (HBeAg) Positive Chronic Hepatitis B (CHB).: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of Peginterferon Alfa-2a (40KD) (PEGASYS®) in Participants With Hepatitis B Envelope Antigen (HBeAg) – Positive Chronic Hepatitis B: Complete Statistical AnalysisIndependent statistical analysis of A Study of Peginterferon Alfa-2a (40KD) (PEGASYS®) in Participants With Hepatitis B Envelope Antigen (HBeAg) - Positive Chronic Hepatitis B: primary endpoint results, effect estimate with confidence interval,…
- A Study of Peginterferon Alfa-2a With or Without Ribavirin in Participants With Chronic Hepatitis D (CHD): Complete Statistical AnalysisIndependent statistical analysis of A Study of Peginterferon Alfa-2a With or Without Ribavirin in Participants With Chronic Hepatitis D (CHD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems: Complete Statistical AnalysisIndependent statistical analysis of A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study of Pharmacokinetics, Efficacy, Safety, Tolerability, of the Combination of Simeprevir (TMC435), Daclatasvir (BMS-790052), and Ribavirin (RBV) in Patients With Recurrent Chronic Hepatitis C Genotype 1b Infection After Orthotopic Liver Transplantation: Complete Statistical AnalysisIndependent statistical analysis of A Study of Pharmacokinetics, Efficacy, Safety, Tolerability, of the Combination of Simeprevir (TMC435), Daclatasvir (BMS-790052), and Ribavirin (RBV) in Patients With Recurrent Chronic Hepatitis C Genotype 1b Infection…
- A Study of Safety and Efficacy of Vaniprevir Administered With Pegylated-Interferon and Ribavirin in Japanese Participants With Chronic Hepatitis C Infection (7009-016): Complete Statistical AnalysisIndependent statistical analysis of A Study of Safety and Efficacy of Vaniprevir Administered With Pegylated-Interferon and Ribavirin in Japanese Participants With Chronic Hepatitis C Infection (7009-016): primary endpoint results, effect estimate with…
- A Study of SHR-1210 in Combination With Apatinib or Chemotherapy in Subjects With Advanced PLC or BTC: Complete Statistical AnalysisIndependent statistical analysis of A Study of SHR-1210 in Combination With Apatinib or Chemotherapy in Subjects With Advanced PLC or BTC: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study of TAK-625 for the Treatment of Alagille Syndrome (ALGS): Complete Statistical AnalysisIndependent statistical analysis of A Study of TAK-625 for the Treatment of Alagille Syndrome (ALGS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of TAK-954 to Treat Gastrointestinal Dysfunction in Adults After Surgery: Complete Statistical AnalysisIndependent statistical analysis of A Study of TAK-954 to Treat Gastrointestinal Dysfunction in Adults After Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of Teduglutide in Japanese Children With Short Bowel Syndrome Aged 4 Months or Older: Complete Statistical AnalysisIndependent statistical analysis of A Study of Teduglutide in Japanese Children With Short Bowel Syndrome Aged 4 Months or Older: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of the Effect of SYN-010 on Subjects With IBS-C: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effect of SYN-010 on Subjects With IBS-C: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Moderately to Severely Active Crohn’s Disease Who Have Inadequately Responded to or Are Intolerant to Biologic Therapy: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to…
- A Study of the Safety and Efficacy of Infliximab(REMICADE ) in Pediatric Patients With Moderately to SeverelyActive Ulcerative Colitis: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of Infliximab(REMICADE ) in Pediatric Patients With Moderately to SeverelyActive Ulcerative Colitis: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of the Safety, Efficacy, and Biomarker Response of BMS-986165 in Participants With Moderate to Severe Ulcerative Colitis: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety, Efficacy, and Biomarker Response of BMS-986165 in Participants With Moderate to Severe Ulcerative Colitis: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of Trastuzumab Emtansine Versus Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Gastric Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Trastuzumab Emtansine Versus Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Gastric Cancer: primary endpoint results, effect estimate with confidence interval,…
- A Study of V419 Given Concomitantly With Prevnar 13™ and RotaTeq™ (V419-006): Complete Statistical AnalysisIndependent statistical analysis of A Study of V419 Given Concomitantly With Prevnar 13™ and RotaTeq™ (V419-006): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) With Concurrent Chemotherapy and Bevacizumab As First-Line Therapy for Metastatic Colorectal Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) With Concurrent Chemotherapy and Bevacizumab As First-Line Therapy for Metastatic Colorectal Cancer: primary endpoint results, effect estimate with confidence interval,…
- A Study on the Correlation Between Interleukin 28B Genotypes With Clinical and Demographic Characteristics in Treatment-Naïve and Treatment-Experienced Patients With Chronic Hepatitis C: Complete Statistical AnalysisIndependent statistical analysis of A Study on the Correlation Between Interleukin 28B Genotypes With Clinical and Demographic Characteristics in Treatment-Naïve and Treatment-Experienced Patients With Chronic Hepatitis C: primary endpoint results, effect estimate…
- A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study to Assess the Effect of Y-90 Therapy on Non-target/Background Liver: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Effect of Y-90 Therapy on Non-target/Background Liver: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study to Assess the Efficacy, Safety and Tolerability of IRL201104 in Adults With Active Eosinophilic Esophagitis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Efficacy, Safety and Tolerability of IRL201104 in Adults With Active Eosinophilic Esophagitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study to Assess the Safety and Effects of Intravenous (IV) Conivaptan on the Hepatic Hemodynamic Response in Cirrhotic Patients: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Safety and Effects of Intravenous (IV) Conivaptan on the Hepatic Hemodynamic Response in Cirrhotic Patients: primary endpoint results, effect estimate with confidence interval,…
- A Study To Assess The Safety And Efficacy Of SU11248 In Patients With Gastrointestinal Stromal Tumor(GIST): Complete Statistical AnalysisIndependent statistical analysis of A Study To Assess The Safety And Efficacy Of SU11248 In Patients With Gastrointestinal Stromal Tumor(GIST): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Brensocatib Tablets in Adults With Cystic Fibrosis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Brensocatib Tablets in Adults With Cystic Fibrosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Non-Alcoholic Steatohepatitis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Non-Alcoholic Steatohepatitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study to Compare How Different Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Handled by the Body of Healthy People and People With Liver Cirrhosis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Compare How Different Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Handled by the Body of Healthy People and People With Liver Cirrhosis: primary endpoint results,…
- A Study to Compare Tenofovir DF Versus the Combination of Emtricitabine Plus Tenofovir DF for the Treatment of Chronic Hepatitis B in Patients With Normal Alanine Aminotransferase (ALT): Complete Statistical AnalysisIndependent statistical analysis of A Study to Compare Tenofovir DF Versus the Combination of Emtricitabine Plus Tenofovir DF for the Treatment of Chronic Hepatitis B in Patients With Normal Alanine Aminotransferase (ALT):…
- A Study to Compare the Number of Patients With Gastro-Oesophageal Reflux Disease (GORD) Achieving Heartburn and Regurgitation Symptom Resolution After Treatment With Either Rabeprazole Sodium 20mg, Esomeprazole 20mg or Esomeprazole 40mg: Complete Statistical AnalysisIndependent statistical analysis of A Study to Compare the Number of Patients With Gastro-Oesophageal Reflux Disease (GORD) Achieving Heartburn and Regurgitation Symptom Resolution After Treatment With Either Rabeprazole Sodium 20mg, Esomeprazole 20mg…
- A Study to Estimate Effect of 4 Different Doses of AZD3355 on Reflux Episodes, Which Patients With Gastroesophageal Reflux Disease (GERD) May Experience: Complete Statistical AnalysisIndependent statistical analysis of A Study to Estimate Effect of 4 Different Doses of AZD3355 on Reflux Episodes, Which Patients With Gastroesophageal Reflux Disease (GERD) May Experience: primary endpoint results, effect estimate…
- A Study to Evaluate How Ontamalimab Works and Assess Its Safety and Tolerability in People With Nonalcoholic Steatohepatitis With Fibrosis Stages 1 to 4: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate How Ontamalimab Works and Assess Its Safety and Tolerability in People With Nonalcoholic Steatohepatitis With Fibrosis Stages 1 to 4: primary endpoint results, effect…
- A Study to Evaluate Preemptive Therapy in Hepatitis C (HCV) Organ Transplant Recipients: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate Preemptive Therapy in Hepatitis C (HCV) Organ Transplant Recipients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…