Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
1,213 results
- Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.: Complete Statistical AnalysisIndependent statistical analysis of Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Effects of Vaporized Marijuana on Neuropathic Pain: Complete Statistical AnalysisIndependent statistical analysis of Effects of Vaporized Marijuana on Neuropathic Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01037088).
- Efficacy and Cost: Benefit Ratio of 0, 1, and 2 Medial Branch Blocks for Lumbar Facet Joint Radiofrequency Denervation: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Cost: Benefit Ratio of 0, 1, and 2 Medial Branch Blocks for Lumbar Facet Joint Radiofrequency Denervation: primary endpoint results, effect estimate with confidence interval, sample-size…
- Efficacy and Safety of Buprenorphine Transdermal Patch in Non-cancer Pain of Moderate Intensity: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Buprenorphine Transdermal Patch in Non-cancer Pain of Moderate Intensity: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Eslicarbazepine Acetate as Preventive Therapy for Subjects With Migraine: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Eslicarbazepine Acetate as Preventive Therapy for Subjects With Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Eslicarbazepine Acetate as Therapy in Subjects With Fibromyalgia: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Eslicarbazepine Acetate as Therapy in Subjects With Fibromyalgia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Efficacy and Safety of Finalgon® Cream Multiple Doses in Acute Low Back Pain: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Finalgon® Cream Multiple Doses in Acute Low Back Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Gabapentin/B-complex Versus Pregabalin in Diabetic Peripheral Neuropathy Pain Management: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Gabapentin/B-complex Versus Pregabalin in Diabetic Peripheral Neuropathy Pain Management: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of IGIV-C in Corticosteroid Dependent Patients With Generalized Myasthenia Gravis: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of IGIV-C in Corticosteroid Dependent Patients With Generalized Myasthenia Gravis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Intravenous Phenobarbital in Neonatal Seizures: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Intravenous Phenobarbital in Neonatal Seizures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04320940).
- Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Efficacy and Safety of Mebeverine + Simethicone in Patients With Functional Bowel Disorders: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Mebeverine + Simethicone in Patients With Functional Bowel Disorders: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHD: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Efficacy and Safety of Single, Low-dose Dexamethasone in Patients After Total Knee Arthroplasty: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Single, Low-dose Dexamethasone in Patients After Total Knee Arthroplasty: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Subcutaneous Administration of TEV-48125 for the Preventive Treatment of Episodic Migraine: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Subcutaneous Administration of TEV-48125 for the Preventive Treatment of Episodic Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Efficacy and Safety of VVZ-149 Injections in Patients Undergoing Laparoscopic Colectomy: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of VVZ-149 Injections in Patients Undergoing Laparoscopic Colectomy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Efficacy and Safety Study of BOTOX® Compared to Topiramate for the Prevention of Chronic Migraine in Adults: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety Study of BOTOX® Compared to Topiramate for the Prevention of Chronic Migraine in Adults: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Efficacy and Safety Study of Sirukumab in Patients With Giant Cell Arteritis: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety Study of Sirukumab in Patients With Giant Cell Arteritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Efficacy and Safety Study of Tesamorelin in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Muscle Wasting: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety Study of Tesamorelin in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Muscle Wasting: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Efficacy and Safety Study of Velaglucerase Alfa in Children and Adolescents With Type 3 Gaucher Disease: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety Study of Velaglucerase Alfa in Children and Adolescents With Type 3 Gaucher Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Efficacy and Safety Study of WTX101 (ALXN1840) in Adult Wilson Disease Patients: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety Study of WTX101 (ALXN1840) in Adult Wilson Disease Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Efficacy and Safety, Long-term Study of Zinc Acetate to Treat Wilson’s Disease in Japan.: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety, Long-term Study of Zinc Acetate to Treat Wilson's Disease in Japan.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Efficacy and Tolerability of BAF312 in Patients With Polymyositis and Dermatomyositis: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Tolerability of BAF312 in Patients With Polymyositis and Dermatomyositis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Efficacy and Tolerability of Ramelteon in Patients With Rapid Eye Movement (REM) Behavior Disorder and Parkinsonism: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Tolerability of Ramelteon in Patients With Rapid Eye Movement (REM) Behavior Disorder and Parkinsonism: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Efficacy and Tolerability of Rimegepant for the Prevention of Migraine in Adults With History of Inadequate Response to Oral Preventive Medications: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Tolerability of Rimegepant for the Prevention of Migraine in Adults With History of Inadequate Response to Oral Preventive Medications: primary endpoint results, effect estimate with confidence…
- Efficacy of 1072nm Infrared Stimulation on Executive Functioning in Dementia: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of 1072nm Infrared Stimulation on Executive Functioning in Dementia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01059877).
- Efficacy of 300 mg Ibuprofen Prolonged-Release Tablets for the Treatment of Pain After Surgical Removal of Impacted Third Molars: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of 300 mg Ibuprofen Prolonged-Release Tablets for the Treatment of Pain After Surgical Removal of Impacted Third Molars: primary endpoint results, effect estimate with confidence interval, sample-size…
- Efficacy of Botulinum Toxin Injections in the Rectus Femoris to Treat Stiff Knee Gait Following Acquired Brain Injury: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of Botulinum Toxin Injections in the Rectus Femoris to Treat Stiff Knee Gait Following Acquired Brain Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Efficacy of Haloperidol vs. Metoclopramide for Treatment of Acute Headaches and Migraines in the Emergency Department: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of Haloperidol vs. Metoclopramide for Treatment of Acute Headaches and Migraines in the Emergency Department: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Efficacy of Intercostal CryoAnalgesia in Robotic Lung Resection: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of Intercostal CryoAnalgesia in Robotic Lung Resection: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05144828).
- Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03859024).
- Efficacy of Quetiapine for Pediatric Delirium: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of Quetiapine for Pediatric Delirium: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02056171).
- Efficacy of Ramelteon on Speeding Up Sleep in Subjects With Delayed Sleep Phase Syndrome: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of Ramelteon on Speeding Up Sleep in Subjects With Delayed Sleep Phase Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Efficacy Study of Light Therapy as an Adjunctive Treatment for Parkinson’s Disease: Complete Statistical AnalysisIndependent statistical analysis of Efficacy Study of Light Therapy as an Adjunctive Treatment for Parkinson's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Efficacy, Safety and Tolerability of E2007 in Levodopa Treated Parkinson’s Disease Patients With Motor Fluctuations: Complete Statistical AnalysisIndependent statistical analysis of Efficacy, Safety and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients With Motor Fluctuations: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Efficacy, Safety and Tolerability of TRI476 (Oxcarbazepine) in Children With Inadequately Controlled Partial Onset Seizures: Complete Statistical AnalysisIndependent statistical analysis of Efficacy, Safety and Tolerability of TRI476 (Oxcarbazepine) in Children With Inadequately Controlled Partial Onset Seizures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Efficacy, Tolerability, and Safety Study of DFN-15: Complete Statistical AnalysisIndependent statistical analysis of Efficacy, Tolerability, and Safety Study of DFN-15: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03006276).
- eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed Patients: Complete Statistical AnalysisIndependent statistical analysis of eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- ELANIndependent statistical analysis of the ELAN randomized trial comparing early versus late initiation of direct oral anticoagulants in patients with ischaemic stroke and atrial fibrillation.
- Electrical Stimulation for the Treatment of Back Pain Using Peripheral Nerve Stimulation (PNS): Complete Statistical AnalysisIndependent statistical analysis of Electrical Stimulation for the Treatment of Back Pain Using Peripheral Nerve Stimulation (PNS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- EMBRACEIndependent statistical analysis of Erenumab - Comprehensive Assessment of Efficacy in (High-Frequency) Episodic Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04252742).
- EMERGEComplete statistical analysis of the randomized phase 3 EMERGE trial of aducanumab in early Alzheimer's disease, including CDR-SB, MMSE, ADAS-Cog 13, ADCS-ADL-MCI, MMRM methodology, confidence intervals, p-values, and trial limitations.
- Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia: Complete Statistical AnalysisIndependent statistical analysis of Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06482125).
- EMMYIndependent statistical analysis of Effectiveness of Quetiapine XR on the Control of Symptoms of Manic Phase of Bipolar Disorder.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- EMPOWERIndependent statistical analysis of Enhancing & Mobilizing the POtential for Wellness & Emotional Resilience Among Surrogate Decision-Makers of ICU Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- EnACTIndependent statistical analysis of Developing and Testing the Enhancing Active Caregiver Training (EnACT) Intervention for Dementia Family Caregivers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- ENCHANTEDIndependent statistical analysis of the ENCHANTED phase 3 factorial trial of low-dose versus standard-dose rtPA and intensive versus standard blood-pressure management in acute ischemic stroke.
- ENCOREIndependent statistical analysis of A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease Who Have Reached Therapeutic Goals With Enzyme Replacement Therapy (ENCORE): primary endpoint results, effect estimate with confidence…