Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
845 results
- BeyondComplete statistical analysis of the Beyond phase 3 trial of interferon beta-1b in relapsing-remitting multiple sclerosis, including trial design, registered endpoints, safety analyses, confidence intervals, and statistical interpretation.
- BFFIndependent statistical analysis of Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03496545).
- Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management: Complete Statistical AnalysisIndependent statistical analysis of Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04567407).
- Bilateral Transversus Abdominis Plane Block With Exparel Verus Continuous Epidural Analgesia With Bupivacaine: Complete Statistical AnalysisIndependent statistical analysis of Bilateral Transversus Abdominis Plane Block With Exparel Verus Continuous Epidural Analgesia With Bupivacaine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- BingocizeIndependent statistical analysis of Bingocize: A Novel Mobile Application for Older Adult Health: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03629912).
- Bioequivalence Study of Paracetamol With Oral Single Dose Administration in Healthy Adult Subjects Under Fasting Conditions: Complete Statistical AnalysisIndependent statistical analysis of Bioequivalence Study of Paracetamol With Oral Single Dose Administration in Healthy Adult Subjects Under Fasting Conditions: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Biomechanical Validation of the Transfer Assessment Instrument (TAI): Complete Statistical AnalysisIndependent statistical analysis of Biomechanical Validation of the Transfer Assessment Instrument (TAI): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01183546).
- Blinded Randomized Placebo-Controlled Study Efficacy and Safety of Injectafer in ID Patients With Fibromyalgia: Complete Statistical AnalysisIndependent statistical analysis of Blinded Randomized Placebo-Controlled Study Efficacy and Safety of Injectafer in ID Patients With Fibromyalgia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Body Weight, Sleep, and Heart Health: Complete Statistical AnalysisIndependent statistical analysis of Body Weight, Sleep, and Heart Health: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03388788).
- BOMPIndependent statistical analysis of Evaluation of a Millimeter Wave Emission Bracelet for Improving Parkinson's Disease Symptoms: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Boosterability of Live Attenuated Japanese Encephalitis (JE) Vaccine in Children Who Have Previously Received Inactivated JE Vaccine: Complete Statistical AnalysisIndependent statistical analysis of Boosterability of Live Attenuated Japanese Encephalitis (JE) Vaccine in Children Who Have Previously Received Inactivated JE Vaccine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Botox + FESIndependent statistical analysis of Efficacy of Functional Electrical Stimulation (FES) in Persons Receiving Botulinum Neurotoxin for Upper Extremity Spasticity: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- BOTOX® Economic Spasticity Trial (BEST): Complete Statistical AnalysisIndependent statistical analysis of BOTOX® Economic Spasticity Trial (BEST): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00549783).
- BOTOX® Prophylaxis in Patients With Chronic Migraine: Complete Statistical AnalysisIndependent statistical analysis of BOTOX® Prophylaxis in Patients With Chronic Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01432379).
- Brain Training to Enhance Frontal Lobe Reasoning: Complete Statistical AnalysisIndependent statistical analysis of Brain Training to Enhance Frontal Lobe Reasoning: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01552473).
- BRAiN-MIndependent statistical analysis of Bringing Relief to Adolescents Naturally Using Melatonin for Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02344316).
- BRAVE-EPAIndependent statistical analysis of Brain Amyloid and Vascular Effects of Eicosapentaenoic Acid: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02719327).
- BRAVOComplete statistical analysis of the BRAVO phase 3 trial of laquinimod in participants with relapsing-remitting multiple sclerosis, including its annualized confirmed relapse-rate analysis, negative binomial regression methodology, confidence intervals, and statistical interpretation.
- Break MBIndependent statistical analysis of A Study of GSK2118436 in BRAF Mutant Metastatic Melanoma to the Brain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Brexpiprazole for the Long-term Treatment of Patients With Agitation Associated With Dementia of the Alzheimer’s Type: Complete Statistical AnalysisIndependent statistical analysis of Brexpiprazole for the Long-term Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's Type: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- BRIDGE Percutaneous Nerve Stimulation for Cesarean Delivery Pain Control: Complete Statistical AnalysisIndependent statistical analysis of BRIDGE Percutaneous Nerve Stimulation for Cesarean Delivery Pain Control: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04365465).
- Brief Cognitive Behavioral Therapy for Chronic Pain to Improve Functioning Among Veterans: Complete Statistical AnalysisIndependent statistical analysis of Brief Cognitive Behavioral Therapy for Chronic Pain to Improve Functioning Among Veterans: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Brigatinib Before Brain Irradiation Trial (B3i Trial): Complete Statistical AnalysisIndependent statistical analysis of Brigatinib Before Brain Irradiation Trial (B3i Trial): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04634110).
- Bryostatin Treatment of Moderately Severe Alzheimer’s Disease: Complete Statistical AnalysisIndependent statistical analysis of Bryostatin Treatment of Moderately Severe Alzheimer's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04538066).
- buffering SLNIndependent statistical analysis of Does Alkalinization Reduce Perceived Pain Levels During Sentinel Lymph Node Imaging?: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- BULLETIndependent statistical analysis of BULLET: Bladder Ultrasound Limits Length (of Time), Expedites Treatment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03860311).
- Buprenorphine and Methadone for Opioid Dependent Chronic Pain Patients: Complete Statistical AnalysisIndependent statistical analysis of Buprenorphine and Methadone for Opioid Dependent Chronic Pain Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00879996).
- Buprenorphine Plus Baclofen to Increase Analgesia in Healthy Volunteers: Complete Statistical AnalysisIndependent statistical analysis of Buprenorphine Plus Baclofen to Increase Analgesia in Healthy Volunteers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04251819).
- Buspirone Therapy for Localized Epilepsy: Complete Statistical AnalysisIndependent statistical analysis of Buspirone Therapy for Localized Epilepsy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01496612).
- Buzzy Versus Vapocoolant Spray: Pediatric Needle Pain Relief: Complete Statistical AnalysisIndependent statistical analysis of Buzzy Versus Vapocoolant Spray: Pediatric Needle Pain Relief: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00919100).
- BWP-ADIndependent statistical analysis of Enhancing Consent for Alzheimer's Research: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00453544).
- C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain: Complete Statistical AnalysisIndependent statistical analysis of C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- CAIndependent statistical analysis of Effectiveness Study of Different Local Anesthetic Mixtures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01243112).
- Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors: Complete Statistical AnalysisIndependent statistical analysis of Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- CAFIIndependent statistical analysis of Coil Assisted Flow Diversion Safety and Performance Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04187573).
- CAIROAn independent statistical analysis of the randomized phase 4 CAIRO trial of clopidogrel and aspirin in ischemic cerebrovascular accident, covering trial design, neurologic endpoints, planned analyses, statistical interpretation, and limitations.
- CAMMPSIndependent statistical analysis of Comprehensive vs. Assisted Management of Mood and Pain Symptoms: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01757301).
- Can Transcranial Direct Current Stimulation Improve Ambulation and Fatigue Resistance in People With MS?: Complete Statistical AnalysisIndependent statistical analysis of Can Transcranial Direct Current Stimulation Improve Ambulation and Fatigue Resistance in People With MS?: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Can Virtual Reality Reduce Pain and Anxiety During Blood Draw: Complete Statistical AnalysisIndependent statistical analysis of Can Virtual Reality Reduce Pain and Anxiety During Blood Draw: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04449341).
- Cannabidiol and Management of Endometriosis Pain: Complete Statistical AnalysisIndependent statistical analysis of Cannabidiol and Management of Endometriosis Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04527003).
- Cannabinoids for Pain Control During Medical Abortion: Complete Statistical AnalysisIndependent statistical analysis of Cannabinoids for Pain Control During Medical Abortion: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03604341).
- Cannabis for Spasticity in Multiple Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of Cannabis for Spasticity in Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00682929).
- CANTOSAn independent statistical analysis of the phase 3 CANTOS trial (NCT01327846), comparing three canakinumab doses with placebo for first adjudicated major adverse cardiovascular events in 10066 participants with atherosclerosis, with hazard ratios,…
- CAPSYSIndependent statistical analysis of Computer-Aided Prevention System: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02444715).
- Carboplatin and Temozolomide (Temodar) for Recurrent and Symptomatic Residual Brain Metastases: Complete Statistical AnalysisIndependent statistical analysis of Carboplatin and Temozolomide (Temodar) for Recurrent and Symptomatic Residual Brain Metastases: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- CARDIOSA-12Independent statistical analysis of Hypoglossal Nerve Stimulation on Cardiovascular Outcomes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03359096).
- Care Partner Assisted Intervention to Improve Oral Health of Individuals With Mild Dementia: Complete Statistical AnalysisIndependent statistical analysis of Care Partner Assisted Intervention to Improve Oral Health of Individuals With Mild Dementia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- CARE-ACTIndependent statistical analysis of Caregivers' and Physicians' Treatment Preference in Parkinson Patients Treated With Neupro® Requiring Caregiver Support: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- CARESComplete statistical analysis of the CARES phase 3 trial of febuxostat versus allopurinol in participants with gout and cardiovascular comorbidities, including MACE, cardiovascular death, myocardial infarction, stroke, and survival-analysis methodology.
- Caring for Babies During the Newborn Screening Blood Test: Complete Statistical AnalysisIndependent statistical analysis of Caring for Babies During the Newborn Screening Blood Test: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02608892).