Statistical methods in oncology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
Hazard ratio
Log-rank test
Cochran-Mantel-Haenszel test
Odds ratio
Cox proportional-hazards model
Fisher exact test
Risk difference
Stratified log-rank test
All oncology trials
2,067 results
- Immunogenicity of Fluzone HD,A High Dose Influenza Vaccine, In Children With Cancer or HIV: Complete Statistical AnalysisIndependent statistical analysis of Immunogenicity of Fluzone HD,A High Dose Influenza Vaccine, In Children With Cancer or HIV: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Immunohistochemical Evaluation of Protein P16 Expression in Ovarian Germ Cell Tumors.: Complete Statistical AnalysisIndependent statistical analysis of Immunohistochemical Evaluation of Protein P16 Expression in Ovarian Germ Cell Tumors.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Immunologic Determinants of Response to Pembrolizumab (MK-3475) in Advanced Melanoma (MK-3475-161/KEYNOTE-161): Complete Statistical AnalysisIndependent statistical analysis of Immunologic Determinants of Response to Pembrolizumab (MK-3475) in Advanced Melanoma (MK-3475-161/KEYNOTE-161): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions: Complete Statistical AnalysisIndependent statistical analysis of Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Immunotherapy With or Without Radiation Therapy for Metastatic Urothelial Cancer: Complete Statistical AnalysisIndependent statistical analysis of Immunotherapy With or Without Radiation Therapy for Metastatic Urothelial Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04936230).
- IMOVAIndependent statistical analysis of Evaluation of Response to the Neoadjuvant Chemotherapy for Advanced Ovarian Cancer by Multimodal Functional Imaging: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Impact of Ga-68 DOTATOC PET-CT Imaging in Management of Neuroendocrine Tumors: Complete Statistical AnalysisIndependent statistical analysis of Impact of Ga-68 DOTATOC PET-CT Imaging in Management of Neuroendocrine Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Impact of Oral Nutritional Supplements on Patients Undergoing Haematopoietic Stem Cell Transplantation: Complete Statistical AnalysisIndependent statistical analysis of Impact of Oral Nutritional Supplements on Patients Undergoing Haematopoietic Stem Cell Transplantation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Impact of Robot-assisted Radical Prostatectomy Technique on Short-term Continence Recovery: Complete Statistical AnalysisIndependent statistical analysis of Impact of Robot-assisted Radical Prostatectomy Technique on Short-term Continence Recovery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02352103).
- Impact of Symbiotic Administration on Intestinal Function of Head and Neck Patients Surgically Treated: Complete Statistical AnalysisIndependent statistical analysis of Impact of Symbiotic Administration on Intestinal Function of Head and Neck Patients Surgically Treated: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- IMpassion030Independent statistical analysis of IMpassion030, a randomized phase 3 trial of atezolizumab plus adjuvant anthracycline/taxane-based chemotherapy versus chemotherapy alone in operable triple-negative breast cancer.
- Implantable Microdevice for In Vivo Drug Sensitivity Testing in Patients With Early Stage, HER2-Positive or Triple Negative Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of Implantable Microdevice for In Vivo Drug Sensitivity Testing in Patients With Early Stage, HER2-Positive or Triple Negative Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size…
- IMpower130Independent statistical analysis of A Study of Atezolizumab in Combination With Carboplatin Plus (+) Nab-Paclitaxel Compared With Carboplatin+Nab-Paclitaxel in Participants With Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC): primary endpoint results,…
- Imprime PGG, Alemtuzumab, and Rituximab in Treating Patients With High Risk Chronic Lymphocytic Leukemia: Complete Statistical AnalysisIndependent statistical analysis of Imprime PGG, Alemtuzumab, and Rituximab in Treating Patients With High Risk Chronic Lymphocytic Leukemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Improving Bowel Preparation for Colonoscopy With a Simple Educational Card: Complete Statistical AnalysisIndependent statistical analysis of Improving Bowel Preparation for Colonoscopy With a Simple Educational Card: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00643682).
- Improving Cancer Pain Management Through Self-Care: Complete Statistical AnalysisIndependent statistical analysis of Improving Cancer Pain Management Through Self-Care: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00708019).
- Improving Urinary Continence and Quality of Life in Prostate Cancer Patients: Complete Statistical AnalysisIndependent statistical analysis of Improving Urinary Continence and Quality of Life in Prostate Cancer Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- IMvigor010Independent statistical analysis of IMvigor010, the randomized phase 3 study of atezolizumab versus observation as adjuvant therapy after surgical resection for high-risk muscle-invasive urothelial carcinoma.
- INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Relapsed or Refractory Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Relapsed or Refractory Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Incorporating MR Imaging Into Prostate Radiotherapy Treatment Planning: Complete Statistical AnalysisIndependent statistical analysis of Incorporating MR Imaging Into Prostate Radiotherapy Treatment Planning: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02470910).
- Increasing the Dose of Survivorship Care Planning in Improving Care and Outcomes in Prostate Cancer Survivors Receiving Androgen Deprivation Therapy: Complete Statistical AnalysisIndependent statistical analysis of Increasing the Dose of Survivorship Care Planning in Improving Care and Outcomes in Prostate Cancer Survivors Receiving Androgen Deprivation Therapy: primary endpoint results, effect estimate with confidence interval,…
- Individualized Adaptive De-escalated Radiotherapy for HPV-related Oropharynx Cancer: Complete Statistical AnalysisIndependent statistical analysis of Individualized Adaptive De-escalated Radiotherapy for HPV-related Oropharynx Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03416153).
- Individualized Stereotactic Body Radiotherapy of Liver Metastases: Complete Statistical AnalysisIndependent statistical analysis of Individualized Stereotactic Body Radiotherapy of Liver Metastases: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01239381).
- Individualized Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery: Complete Statistical AnalysisIndependent statistical analysis of Individualized Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis: Complete Statistical AnalysisIndependent statistical analysis of Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Infigratinib in Recurrent High-Grade Glioma Patients: Complete Statistical AnalysisIndependent statistical analysis of Infigratinib in Recurrent High-Grade Glioma Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04424966).
- Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis: Complete Statistical AnalysisIndependent statistical analysis of Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Influenza Vaccine Post Allogeneic Transplant: Complete Statistical AnalysisIndependent statistical analysis of Influenza Vaccine Post Allogeneic Transplant: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01215981).
- Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes: Complete Statistical AnalysisIndependent statistical analysis of Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes: primary endpoint results,…
- Inhibition of Oral Tumorigenesis by Antitumor B: Complete Statistical AnalysisIndependent statistical analysis of Inhibition of Oral Tumorigenesis by Antitumor B: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04278989).
- INSIGHT 2An independent statistical analysis of INSIGHT 2 (NCT03940703), a phase 2 study of tepotinib plus osimertinib in osimertinib-relapsed MET-amplified non-small cell lung cancer.
- InterAACTIndependent statistical analysis of the InterAACT phase 2 randomized trial comparing cisplatin plus 5-FU with carboplatin plus weekly paclitaxel in advanced anal squamous cell carcinoma.
- INTERLACEIndependent statistical analysis of the INTERLACE phase 3 trial evaluating induction chemotherapy plus chemoradiation as first line treatment for locally advanced cervical cancer. Includes trial design, endpoint methodology, statistical interpretation, and limitations.
- Investigate Safety, Pharmacokinetics and Pharmacodynamics of GSK2118436 & GSK1120212: Complete Statistical AnalysisIndependent statistical analysis of Investigate Safety, Pharmacokinetics and Pharmacodynamics of GSK2118436 & GSK1120212: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01072175).
- Investigation of a New Trial Drug (FE200486) in Prostate Cancer Patients: Complete Statistical AnalysisIndependent statistical analysis of Investigation of a New Trial Drug (FE200486) in Prostate Cancer Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Investigation of GSK2879552 in Subjects With Relapsed/Refractory Small Cell Lung Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of Investigation of GSK2879552 in Subjects With Relapsed/Refractory Small Cell Lung Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Involving Family to Improve Communication in Breast Cancer Care: Complete Statistical AnalysisIndependent statistical analysis of Involving Family to Improve Communication in Breast Cancer Care: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03283553).
- IPASSIndependent statistical analysis of the randomized phase 3 IPASS trial of gefitinib versus carboplatin/paclitaxel in non-small cell lung cancer, including trial design, progression-free survival, planned statistical methods, safety, and interpretation.
- IPATunity130Independent statistical analysis of A Study of Ipatasertib in Combination With Paclitaxel as a Treatment for Participants With PIK3CA/AKT1/PTEN-Altered, Locally Advanced or Metastatic, Triple-Negative Breast Cancer or Hormone Receptor-Positive, HER2-Negative Breast Cancer:…
- IPATunity150Independent statistical analysis of IPATunity150, evaluating ipatasertib plus palbociclib and fulvestrant versus placebo plus palbociclib and fulvestrant in hormone receptor positive and HER2 negative locally advanced unresectable or metastatic breast cancer.
- Ipilimumab and Local Radiation for Selected Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of Ipilimumab and Local Radiation for Selected Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01769222).
- Irinotecan and Carboplatin in Treating Patients With Metastatic or Recurrent Small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of Irinotecan and Carboplatin in Treating Patients With Metastatic or Recurrent Small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With RAS Wild-Type Locally Advanced or Metastatic Colorectal Cancer That Cannot Be Removed by Surgery: Complete Statistical AnalysisIndependent statistical analysis of Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With RAS Wild-Type Locally Advanced or Metastatic Colorectal Cancer That Cannot Be Removed by Surgery: primary endpoint results,…
- Irinotecan and Cisplatin in Treating Patients Who Are Undergoing Surgery For Locally Advanced Cancer of the Stomach or Gastroesophageal Junction: Complete Statistical AnalysisIndependent statistical analysis of Irinotecan and Cisplatin in Treating Patients Who Are Undergoing Surgery For Locally Advanced Cancer of the Stomach or Gastroesophageal Junction: primary endpoint results, effect estimate with confidence interval,…
- Irofulven in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cancer: Complete Statistical AnalysisIndependent statistical analysis of Irofulven in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma: Complete Statistical AnalysisIndependent statistical analysis of Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Itacitinib + Everolimus in Hodgkin Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Itacitinib + Everolimus in Hodgkin Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03697408).
- Ixazomib Citrate in Treating Patients With Relapsed Multiple Myeloma That Is Not Refractory to Bortezomib: Complete Statistical AnalysisIndependent statistical analysis of Ixazomib Citrate in Treating Patients With Relapsed Multiple Myeloma That Is Not Refractory to Bortezomib: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- IXTENDIndependent statistical analysis of Randomized Study Evaluating Ixabepilone Plus Capecitabine or Docetaxel Plus Capecitabine in Metastatic Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…