Statistical methods in oncology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
Hazard ratio
Log-rank test
Cochran-Mantel-Haenszel test
Odds ratio
Cox proportional-hazards model
Fisher exact test
Risk difference
Stratified log-rank test
All oncology trials
2,067 results
- Magnetic Resonance Imaging (MRI) Brachytherapy Applicator Study: Complete Statistical AnalysisIndependent statistical analysis of Magnetic Resonance Imaging (MRI) Brachytherapy Applicator Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01706705).
- Magnetic Resonance Spectroscopy Imaging in Predicting Response to Vorinostat and Temozolomide in Patients With Recurrent or Progressive Glioblastoma: Complete Statistical AnalysisIndependent statistical analysis of Magnetic Resonance Spectroscopy Imaging in Predicting Response to Vorinostat and Temozolomide in Patients With Recurrent or Progressive Glioblastoma: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- MAGNIFYIndependent statistical analysis of Lenalidomide Plus Rituximab Followed by Lenalidomide Versus Rituximab Maintenance for Relapsed/Refractory Follicular, Marginal Zone or Mantle Cell Lymphoma.: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- MAGNITUDEIndependent statistical analysis of the phase 3 MAGNITUDE trial of niraparib in combination with abiraterone acetate and prednisone versus abiraterone acetate and prednisone in castration-resistant prostate cancer, including rPFS, hazard ratios, confidence…
- MAINTAINAn educational statistical analysis of the randomized phase 2 MAINTAIN trial evaluating ribociclib after progression on CDK4/6 inhibition in patients with HR+ HER2- advanced breast cancer.
- MAJICAn independent statistical analysis of the phase 3 MAJIC trial evaluating acalabrutinib plus venetoclax versus venetoclax plus obinutuzumab in previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma.
- Malignant Pleural Effusion With ZD6474: Complete Statistical AnalysisIndependent statistical analysis of Malignant Pleural Effusion With ZD6474: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00402896).
- Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia: Complete Statistical AnalysisIndependent statistical analysis of Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Managing Distress in Malignant Brain Cancer: Complete Statistical AnalysisIndependent statistical analysis of Managing Distress in Malignant Brain Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05087095).
- Managing Pain and Symptom Burden Caused by Chemotherapy in People With Myeloma or Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Managing Pain and Symptom Burden Caused by Chemotherapy in People With Myeloma or Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- MANGO OV2Independent statistical analysis of MANGO OV2, a phase 4 single-group ovarian cancer study evaluating clinical and biological prognostic factors during carboplatin, paclitaxel, and bevacizumab treatment.
- MANTAIndependent statistical analysis of the randomized phase 2 MANTA trial of AZD2014 in combination with fulvestrant in metastatic or advanced estrogen receptor positive breast cancer, including trial design, progression-free survival, planned analysis,…
- MAPSIndependent statistical analysis of MRI-Mapped Dose-Escalated Salvage Radiotherapy Post-Prostatectomy: The MAPS Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01411345).
- Massive Iron Deposit Assessment: Complete Statistical AnalysisIndependent statistical analysis of Massive Iron Deposit Assessment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01572922).
- Mast Cell Activation Test in Allergic Disease: Complete Statistical AnalysisIndependent statistical analysis of Mast Cell Activation Test in Allergic Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03406325).
- Mastectomy Flap Temperature Study: Complete Statistical AnalysisIndependent statistical analysis of Mastectomy Flap Temperature Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05395936).
- MasterKey-01Independent statistical analysis of A Study of BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Mature B-Cell Lymphoma And Leukemia Study III: Complete Statistical AnalysisIndependent statistical analysis of Mature B-Cell Lymphoma And Leukemia Study III: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01046825).
- McCAVEIndependent statistical analysis of A Study Comparing the Efficacy and Safety of Vanucizumab and FOLFOX With Bevacizumab and FOLFOX in Participants With Untreated Metastatic Colorectal Cancer: primary endpoint results, effect estimate with…
- MDX-010 in Treating Patients With Stage IV Pancreatic Cancer That Cannot Be Removed By Surgery: Complete Statistical AnalysisIndependent statistical analysis of MDX-010 in Treating Patients With Stage IV Pancreatic Cancer That Cannot Be Removed By Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- MDX1106-01Independent statistical analysis of A Study of MDX-1106 in Patients With Selected Refractory or Relapsed Malignancies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Measuring Fatty Acid Oxidation in Gliomas Using 18F-FPIA PET/MRI: Complete Statistical AnalysisIndependent statistical analysis of Measuring Fatty Acid Oxidation in Gliomas Using 18F-FPIA PET/MRI: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04097535).
- MEK InhibitorIndependent statistical analysis of MEK Inhibitor PD-0325901 Trial in Adolescents and Adults With NF1: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02096471).
- MEK Inhibitor AZD6244 in Treating Patients With Stage III or Stage IV Melanoma: Complete Statistical AnalysisIndependent statistical analysis of MEK Inhibitor AZD6244 in Treating Patients With Stage III or Stage IV Melanoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- MEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC): Complete Statistical AnalysisIndependent statistical analysis of MEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Melatonin Postoperative Sleep Study in Breast Cancer Patients: Complete Statistical AnalysisIndependent statistical analysis of Melatonin Postoperative Sleep Study in Breast Cancer Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00506064).
- Melatonin Supplementation for Cancer-related Fatigue in Patients Receiving Radiotherapy: Complete Statistical AnalysisIndependent statistical analysis of Melatonin Supplementation for Cancer-related Fatigue in Patients Receiving Radiotherapy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02332928).
- Melphalan and Panobinostat (LBH589) for the Treatment of Patients With Recurrent Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Melphalan and Panobinostat (LBH589) for the Treatment of Patients With Recurrent Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Men Together Making a Difference: Reducing HIV/STD Risk Behavior Among South African Men: Complete Statistical AnalysisIndependent statistical analysis of Men Together Making a Difference: Reducing HIV/STD Risk Behavior Among South African Men: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Menopur® Versus Follistim® in Polycystic Ovarian Syndrome (PCOS): Complete Statistical AnalysisIndependent statistical analysis of Menopur® Versus Follistim® in Polycystic Ovarian Syndrome (PCOS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00805935).
- MERCURY IIAn independent statistical analysis of MERCURY II (NCT02005965), a study evaluating CRM positivity and quality of life outcomes in low rectal cancer surgery.
- Merits of Performing a Modified Template Retroperitoneal Lymph Node Dissection: Complete Statistical AnalysisIndependent statistical analysis of Merits of Performing a Modified Template Retroperitoneal Lymph Node Dissection: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00751140).
- MERMAID-1Independent statistical analysis of Phase III Study to Determine the Efficacy of Durvalumab in Combination With Chemotherapy in Completely Resected Stage II-III Non-small Cell Lung Cancer (NSCLC): primary endpoint results, effect estimate…
- Mesothelin-Targeted Immunotoxin LMB-100 in Combination With SEL-110 in Subjects With Malignant Pleural or Peritoneal Mesothelioma: Complete Statistical AnalysisIndependent statistical analysis of Mesothelin-Targeted Immunotoxin LMB-100 in Combination With SEL-110 in Subjects With Malignant Pleural or Peritoneal Mesothelioma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia: Complete Statistical AnalysisIndependent statistical analysis of Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery: Complete Statistical AnalysisIndependent statistical analysis of Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01433913).
- Metformin in Non Small Cell Lung Cancer (NSCLC): Complete Statistical AnalysisIndependent statistical analysis of Metformin in Non Small Cell Lung Cancer (NSCLC): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02285855).
- Metformin Pharmacology in Human Cancers: A Proof of Principle Study: Complete Statistical AnalysisIndependent statistical analysis of Metformin Pharmacology in Human Cancers: A Proof of Principle Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03477162).
- Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer: Complete Statistical AnalysisIndependent statistical analysis of Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia: Complete Statistical AnalysisIndependent statistical analysis of Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Methotrexate With or Without Cyclophosphamide in Treating Patients With Lymphocytic Leukemia: Complete Statistical AnalysisIndependent statistical analysis of Methotrexate With or Without Cyclophosphamide in Treating Patients With Lymphocytic Leukemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Methotrexate, Vincristine, Pegylated L-Asparaginase and Dexamethasone (MOAD) in Acute Lymphoblastic Leukemia (ALL) Salvage: Complete Statistical AnalysisIndependent statistical analysis of Methotrexate, Vincristine, Pegylated L-Asparaginase and Dexamethasone (MOAD) in Acute Lymphoblastic Leukemia (ALL) Salvage: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- METROIndependent statistical analysis of Metformin and Carbohydrate Restriction With Platinum Based Chemotherapy In Stage IIIB/IV Non-Squamous Non-Small Cell Lung Cancer (NS-NSCLC): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Metvix PDT in Participant With “High Risk” Basal Cell Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of Metvix PDT in Participant With "High Risk" Basal Cell Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00473343).
- MGC018 With or Without MGA012 in Advanced Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of MGC018 With or Without MGA012 in Advanced Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03729596).
- Microscopic Fluorescence-guided Vestibular Schwannoma Resection Using Fluorescein Sodium and YELLOW 560: Complete Statistical AnalysisIndependent statistical analysis of Microscopic Fluorescence-guided Vestibular Schwannoma Resection Using Fluorescein Sodium and YELLOW 560: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma: Complete Statistical AnalysisIndependent statistical analysis of Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Midostaurin and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia and FLT3 Mutation: Complete Statistical AnalysisIndependent statistical analysis of Midostaurin and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia and FLT3 Mutation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- MINDACTIndependent statistical analysis of the MINDACT phase 3 trial, examining genetic testing and clinical assessment in determining the need for chemotherapy in women with breast cancer involving no more than 3 lymph…
- Mindfulness Therapy for Individuals With Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of Mindfulness Therapy for Individuals With Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01565980).