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Computing Boundaries and Power · Tutorial 236 of 699

Truncating the Gaussian State Space

You will learn to select finite integration limits for Gaussian sequential statistics and bound how much those limits can change a boundary-crossing probability.

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What You'll Learn

  • Define finite state-space truncation for a Gaussian sequential statistic.
  • Calculate the probability omitted at each look from its marginal Gaussian distribution.
  • Bound the effect of truncation across several looks without assuming independence.
  • Choose limits to meet a specified total omitted-probability tolerance.
  • Diagnose when a finite integration range is inadequate and distinguish truncation from quadrature error.

Why a Gaussian State Space Is Truncated

A Gaussian test statistic has support over the entire real line, but numerical integration must use a finite range or a finite collection of states. Choosing that range is not merely a computational convenience: probability outside it is omitted from the calculation. The key question is therefore not whether the range is finite, but whether the omitted probability is small enough for the intended accuracy.

Consider a group-sequential design with looks at information levels \(I_1<\cdots<I_K\). Write \(X_j\) for the standardized statistic at look \(j\). In the canonical Gaussian model with constant drift \(\theta\), assume the increments of the underlying information-scale process are independent Gaussian increments. Then \(X_j\sim N(\theta\sqrt{I_j},1)\), and, for \(j>1\),

$$ X_j\mid X_{j-1}=x\sim N\left(\sqrt{\frac{I_{j-1}}{I_j}}x+ \theta\frac{I_j-I_{j-1}}{\sqrt{I_j}}, 1-\frac{I_{j-1}}{I_j}\right). $$

In particular, under \(H_0\), set \(\theta=0\). The transition variance is positive because information increases between looks. The marginal distribution at look \(j\) has mean \(\mu_j=\theta\sqrt{I_j}\) and variance 1. The bounds below use these marginal distributions; dependence between looks is allowed and is not ignored.

Definition: At look \(j\), state-space truncation restricts integration over \(X_j\) to a finite interval \([l_j,u_j]\). The omitted marginal probability is $$ q_j=P(X_j<l_j)+P(X_j>u_j) =\Phi(l_j-\mu_j)+1-\Phi(u_j-\mu_j), $$ where \(\Phi\) is the standard normal cumulative distribution function and \(X_j\sim N(\mu_j,1)\). For a collection of looks, the total truncation error is the difference between the desired boundary-crossing probability and the probability calculated using only paths retained at every integrated look.

Intervals need not be centered at zero. Under a nonzero drift, the marginal states are shifted, so limits chosen for a null calculation may omit substantially more probability under an alternative. Limits can also differ from look to look. What matters for the error guarantee is the omitted probability under the parameter value whose crossing probability is being calculated.

A Bound on the Effect of Truncation

Let \(A\) be the event of crossing a specified sequential boundary by the final look. Define \(T\) as the event that at least one state lies outside its integration interval at a look used in the calculation. The truncated calculation retains the crossing probability from paths that never leave the chosen intervals, \(P(A\cap T^c)\). Therefore its absolute error is bounded as follows.

$$ 0\le P(A)-P(A\cap T^c) =P(A\cap T) \le P(T) \le \sum_{j=1}^{K}P(X_j\notin[l_j,u_j]) =\sum_{j=1}^{K}q_j. $$

The last inequality is the union bound. It does not require independent looks; sequential statistics are generally dependent. It can be conservative because a path may be outside the range at more than one look, and not every omitted path would have crossed a boundary. Nevertheless, it gives a transparent guarantee: if the sum of marginal tail probabilities is at most \(\varepsilon\), truncation changes the crossing probability by at most \(\varepsilon\).

This is a bound on truncation error, not on every source of numerical error. Numerical quadrature and discretization can introduce additional error. If the calculation also approximates integrals, its total discrepancy from the target is bounded by the truncation bound plus a bound for those other errors, when such bounds are available. In practice, report the chosen limits and the tail-probability bound rather than treating a finely computed integral as automatically accurate.

Worked Example: A Common Four-Standard-Deviation Range

Suppose five looks are evaluated under \(H_0\), and the marginal statistic at each look is standard normal. Use \([-4,4]\) at every look. Find the per-look omitted probability and bound the effect on a crossing probability.

At each look, \(\mu_j=0\), so $$ q_j=\Phi(-4)+1-\Phi(4)=2\Phi(-4) =2(0.0000316712)=0.0000633425. $$

Applying the union bound over five looks gives $$ \sum_{j=1}^{5}q_j =5(0.0000633424837)=0.000316712. $$

Thus the truncated crossing probability is no larger than the full crossing probability, and the difference is at most approximately \(0.0003167\), or \(0.0317\) percentage points. This is a guarantee under the stated null model and marginal distributions, not a claim that the actual error equals the bound.

Choosing Limits for a Probability Tolerance

A practical way to select limits is to allocate a total tail-probability budget across looks. Choose nonnegative values \(\varepsilon_j\) whose sum is no greater than the desired tolerance \(\varepsilon\). Then select \(l_j\) and \(u_j\) so that \(q_j\le\varepsilon_j\). A symmetric interval around the marginal mean is convenient when tails are balanced, but asymmetric limits can be more efficient when the mean is shifted or one side of the state range is more important.

For a unit-variance marginal distribution, a symmetric interval \([\mu_j-c_j,\mu_j+c_j]\) has omitted probability \(2\Phi(-c_j)\). Thus a sufficient condition for the total truncation error to be at most \(\varepsilon\) is $$ \sum_{j=1}^{K}2\Phi(-c_j)\le\varepsilon. $$

Equal allocation uses the same tail probability at every look, but it is not required. For example, more of the budget may be allocated to looks with wider integration ranges or to looks where the boundary geometry makes omitted states especially relevant. The union-bound guarantee still holds as long as the allocated probabilities sum to no more than the tolerance.

Worked Example: Limits Under a Positive Drift

Suppose three marginal statistics have unit variances and means \(0\), \(0.5\), and \(1\), respectively. Use the common limits \([-4,4]\). Calculate the omitted probability at each look and the total bound. The mean shift represents the assumed model for this calculation; it does not change the variance.

At the first look, $$ q_1=\Phi(-4)+1-\Phi(4)=0.0000633425. $$

At the second look, standardizing the endpoints by subtracting the mean \(0.5\) gives $$ q_2=\Phi(-4.5)+1-\Phi(3.5) =0.00000339767+0.000232629 =0.000236027. $$

At the third look, the standardized endpoints are \(-5\) and \(3\), so $$ q_3=\Phi(-5)+1-\Phi(3) =0.000000286652+0.00134990 =0.00135019. $$

Using the unrounded tail probabilities when summing, $$ \sum_{j=1}^{3}q_j =0.0000633424837+0.000236026752+0.0013501846832 =0.00164955. $$

The upper tail at the third look dominates because the limits are not centered on that look’s marginal mean. The total truncation error is bounded by about \(0.001650\), or \(0.1650\) percentage points. If that is too large for the intended accuracy, the upper limit should be increased, particularly at the third look. A symmetric interval around zero would not be an equally effective choice under this drift.

Worked Example: Meeting a Total Error Budget

For four looks, suppose each marginal statistic has variance 1, but its mean may vary by look. The calculation must have a truncation bound below \(0.0001\). Choose intervals centered at each look’s marginal mean with half-width \(4.3\).

For every look, $$ q_j=2\Phi(-4.3) =2(0.00000853990) =0.0000170798. $$

The union bound is therefore $$ \sum_{j=1}^{4}q_j =4(0.0000170798) =0.0000683192<0.0001. $$

The chosen limits meet the requested truncation tolerance even though the marginal means differ, because each interval is centered at its own mean. If the computed truncated crossing probability is \(0.02540\), then the full crossing probability lies between \(0.02540\) and approximately \(0.02547\), provided the integration over retained paths is exact. Any quadrature error must be considered separately.

How to Apply the Bound in a Recursive Calculation

The survivor-density recursion carries probability forward only for paths that have not crossed a boundary. Restricting each integration to a finite state interval discards additional mass. The following procedure makes that omission explicit before interpreting the resulting crossing estimate.

1
Specify the model and parameter scenario.
State the marginal mean and variance of \(X_j\) at each look. A null crossing probability and an alternative crossing probability can require different tail calculations.
2
Set candidate limits.
Choose finite \(l_j\) and \(u_j\) that cover the state range used by the recursion and retain the relevant boundary locations.
3
Calculate omitted marginal probabilities.
Evaluate \(q_j=\Phi(l_j-\mu_j)+1-\Phi(u_j-\mu_j)\) at full working precision for each look.
4
Sum the tail probabilities.
If \(\sum_j q_j\) exceeds the acceptable truncation error, widen or reposition the intervals and recalculate.
5
Report truncation separately.
State the limits and the bound alongside the crossing estimate. Do not describe the bound as the observed error or as a bound on quadrature error.

For a boundary-crossing calculation, limits should include the boundary locations at each look. If a boundary lies outside the interval, crossings in that excluded region are omitted; the tail bound still controls the probability of such omissions, but a range that cuts through a region of substantial boundary-crossing probability is a warning to widen the interval.

Diagnostics, Alternatives, and Limitations

A useful diagnostic is to compare the calculated tail bound with the precision needed for the scientific or design decision. A bound of \(0.001\) may be negligible for a rough power assessment but unacceptable when distinguishing crossing probabilities that differ by \(0.0002\). Also inspect the separate \(q_j\) values: a small total can conceal one look that contributes most of the error. Under a nonzero drift, check both tails at every look rather than assuming symmetry around zero.

State-space truncation is different from the main alternatives for Gaussian integration. A Gaussian transition quadrature can approximate an integral over an unbounded transition distribution without imposing the same state interval, though a finite numerical rule still has its own approximation error. Conversely, restricting a state grid gives direct control over where the recursion is evaluated, but it introduces a tail omission that must be budgeted. Direct multivariate Gaussian probability calculations offer another way to evaluate some crossing events, but they do not make tail or numerical accuracy checks unnecessary.

The union bound is intentionally general and can be conservative. It adds marginal tail probabilities even when the same rare path contributes to several looks, and it counts tail paths that would not contribute to the event of interest. A tighter event-specific bound may be possible, but the simple sum is dependable and does not require modeling dependence beyond the marginal distributions. Its limitations are equally important: it does not quantify quadrature error, grid discretization error, or errors from an incorrect Gaussian model.

Common Mistakes

  • Using a null tail bound for an alternative calculation. Under drift, the marginal means shift. Recalculate \(q_j\) under the parameter value used for the crossing probability.
  • Assuming look independence. The union bound applies to dependent looks; multiplying one tail probability by the number of looks is valid only when those probabilities are equal, not because the looks are independent.
  • Rounding before summing. Retain adequate precision in each tail probability, sum first, and round the final bound. For example, \(3\{\Phi(-4.5)+\Phi(-3.5)\}=0.000708080\ldots\), not a value obtained by multiplying a prematurely rounded tail sum.
  • Treating the tail bound as total numerical error. It bounds only the error from state-space truncation. Quadrature and discretization need separate assessment.
  • Calling the bound the actual error. The actual error can be much smaller, because not all omitted paths cross a boundary and the union bound can count a path more than once.
Key takeaway: For unit-variance Gaussian states, compute the marginal probability outside each finite integration interval and sum those probabilities. The sum is a valid upper bound on the change in a boundary-crossing probability caused by truncation, whether or not the looks are independent.

Check Your Understanding

Try each question, then compare your reasoning with the solutions.

  1. At one look, \(X\sim N(0,1)\) and the integration interval is \([-3,3]\). Express the omitted probability using \(\Phi\). Is it a one-sided or two-sided tail probability?
  2. Three looks each have omitted marginal probability \(0.0002\). Give a valid upper bound on the probability that at least one state is omitted. Does the bound require independent looks?
  3. At a look under an alternative, \(X\sim N(0.8,1)\), and the range is \([-4,4]\). Which tail is larger, and why?
  4. A truncated calculation gives a crossing probability of \(0.0120\), and the sum of marginal tail probabilities is \(0.0003\). Give the interval containing the full crossing probability, assuming integration over retained states is exact.
  5. Name one error source that is not covered by the sum of marginal tail probabilities.

Solutions. (1) The omitted probability is \(\Phi(-3)+1-\Phi(3)=2\Phi(-3)\), a two-sided tail probability. (2) The union bound is \(3(0.0002)=0.0006\); independence is not required. (3) The upper tail is larger because the mean is shifted toward the upper endpoint: \(4-0.8=3.2\) standard deviations, whereas \(-4\) is \(4.8\) standard deviations below the mean. (4) The truncated value omits nonnegative crossing mass, so the full value lies from \(0.0120\) to at most \(0.0123\). (5) Quadrature error or state-grid discretization error is not covered by the tail-probability bound.

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