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Partial Identification and Bounds · Tutorial 434 of 699

Diagnosing Whether Bounds Are Informative

You will learn to assess an identified interval’s width and location, interpret boundary cases around zero and decision thresholds, and separate data-driven informativeness from assumption-driven narrowing.

Advanced 11 min read

What You'll Learn

  • Calculate an identified interval’s width and interpret it in the outcome’s units.
  • Decide whether all, none, or only some identified effects meet a threshold.
  • Handle equality at zero and at a decision boundary correctly.
  • Distinguish a narrow interval supported by the data from one narrowed by added assumptions.
  • Recognize when sampling uncertainty makes an endpoint-based conclusion premature.
  • Compare bounds with point estimates and sensitivity analyses without treating them as interchangeable.

What Makes an Identified Interval Informative?

A partially identified effect is not summarized by one value, but by a set of values compatible with the observed data and the stated assumptions. That set can still answer useful questions. It may establish the sign of an effect, rule out a decision threshold, or show that every compatible effect is practically small. It can also be too wide to distinguish materially different conclusions.

In this tutorial, write the identified interval for an effect \(\tau\) as \([L,U]\), where \(L\) and \(U\) are its lower and upper endpoints and \(L\leq U\). The interval is taken to be closed: both endpoints are included. Its width is \(W=U-L\). The endpoints and width have the same units as \(\tau\), so a width is meaningful only when interpreted on the outcome’s scale and in the decision context.

Definition: An identified interval is informative for a particular question when it restricts the compatible values of the causal effect enough to answer that question. Informativeness is question-specific: an interval may settle the sign of an effect while remaining too wide to settle whether the effect exceeds a clinically or practically important threshold.

There is no universal numerical cutoff for a “narrow” interval. A width of 2 may be small for an outcome measured in thousands of dollars and large for an outcome measured in millimeters. Even after units are fixed, the relevant comparison depends on what effect sizes would matter. Assess width alongside the interval’s location and a prespecified substantive scale, such as a minimally important effect or a decision threshold.

Width, Location, and a Short Justification

The width gives the range of effects still compatible with the analysis. If \(W\) is small relative to the range of effects considered substantively important, the interval is compact for that purpose. If \(W\) spans effects with different practical implications, the interval may be uninformative for a fine-grained decision even if its endpoints are estimated precisely.

Location answers a different question. An interval can be wide but entirely positive, which settles the sign, or narrow but close to zero, which may not establish an important effect. To see why endpoint comparisons answer these questions, let \(\tau\) denote any compatible effect. Since \(L\leq\tau\leq U\), comparisons of both endpoints with zero or a threshold determine what all compatible values can do.

$$ L\leq \tau\leq U $$

For example, if \(L>0\), then \(\tau\geq L>0\) for every compatible effect, so the effect is strictly positive throughout the interval. If \(L\leq 0\leq U\), zero is among the interval’s values, so the interval does not establish a strictly positive or strictly negative effect. The same endpoint logic applies to a decision threshold \(c\), but equality must be handled according to how the threshold is defined.

Endpoint rules: If the question is whether \(\tau\) is strictly positive, \(L>0\) establishes positivity for every compatible effect, and \(U<0\) establishes negativity for every compatible effect. If zero lies in \([L,U]\), the sign is not settled. For a “meets or exceeds \(c\)” criterion, every compatible effect meets it when \(L\geq c\), none meets it when \(U<c\), and the interval contains values below \(c\) and values at or above \(c\) when \(L<c\leq U\). For a strictly greater-than-\(c\) criterion, every effect exceeds \(c\) when \(L>c\), and none does when \(U\leq c\).

Thus, when \(L<c\leq U\), the interval includes values below the threshold and values at or above it; it does not settle whether the threshold is met. If \(L<c<U\), it has values strictly on both sides. At the boundary \(U=c\), it includes values below \(c\) and the value \(c\), but no values above \(c\). That boundary still leaves the “at least \(c\)” question unsettled: some compatible effects meet the threshold and some do not.

Worked Example: A Narrow Interval That Settles the Sign

Suppose a hypothetical analysis reports an identified interval of \([0.018,0.041]\) for a treatment effect measured as a risk difference. The units are proportions, so these endpoints correspond to increases of 1.8 and 4.1 percentage points.

The width is \[ W=U-L=0.041-0.018=0.023, \] or 2.3 percentage points. Since \(L=0.018>0\), every effect in the interval is positive. The interval therefore settles the sign under the stated identification assumptions.

Now suppose the decision question is whether the increase is at least 3 percentage points, so \(c=0.030\). The endpoints satisfy \(0.018<0.030<0.041\). Some compatible effects are below 3 percentage points and some are above it, so the interval does not settle that decision question. Its sign information is strong, but its threshold information is not.

The conclusion is about the set of effects compatible with the analysis, not a claim that the effect equals the midpoint or that all values are equally plausible. The midpoint, \( (0.018+0.041)/2=0.0295\), is not a point estimate justified by the bounds alone.

Reading Intervals Against Decision Thresholds

A decision threshold should be stated in the same units as the effect and with its direction made explicit. A minimum beneficial effect might be “at least 3 mmHg reduction,” while a safety criterion might be “increase in risk less than 1 percentage point.” These are not interchangeable questions: “at least” includes equality, while “greater than” does not.

Worked Example: The Upper Endpoint Equals the Threshold

Consider a hypothetical identified interval \([2.4,5.0]\) mmHg for a reduction in systolic blood pressure. A decision rule calls a reduction of at least 5.0 mmHg important. Thus \(c=5.0\), with the rule \(\tau\geq c\).

The width is \(5.0-2.4=2.6\) mmHg. Because \(L<c=U\), the interval contains reductions below 5.0 mmHg and the endpoint reduction of exactly 5.0 mmHg. It contains no value above 5.0 mmHg.

Consequently, the bounds do not show that all compatible effects meet the “at least 5.0” criterion, and they do not show that none meet it: the endpoint itself meets the criterion. If the rule instead required a reduction strictly greater than 5.0 mmHg, no value in this interval would satisfy it, because \(U=c\). Reporting merely that the interval “crosses the threshold” would be imprecise; stating the rule and comparing the endpoints gives the correct conclusion.

Threshold analysis can also reveal useful negative conclusions. If \(U<c\), the data and assumptions rule out meeting an “at least \(c\)” criterion. If \(L\geq c\), they establish that every compatible effect meets it. If \(L<c\leq U\), the bounds leave the decision unresolved. “Unresolved” does not mean that the effect is zero, that the threshold is equally likely to be met or missed, or that no decision can be made using other considerations.

Data-Driven Precision Versus Assumption-Driven Precision

A narrow interval is not automatically evidence that the observed data strongly determine the effect. Bounds are calculated relative to a set of maintained assumptions. Additional restrictions can remove values from the identified set and narrow the interval, even when the observed data have not changed. That narrowing may be useful, but its source is the restriction, not new empirical information.

One way to diagnose the source of informativeness is to compare nested analyses using the same data. Let \(S_0\) be the set of effects compatible with the data and a baseline set of assumptions. Suppose an additional assumption retains only effects in \(S_1\), with \(S_1\subseteq S_0\). The interval implied by \(S_1\) cannot be wider than the interval implied by \(S_0\), but its smaller width alone does not establish that the extra restriction is credible.

$$ S_1\subseteq S_0 \quad\Longrightarrow\quad \inf(S_0)\leq \inf(S_1)\leq \sup(S_1)\leq \sup(S_0) $$

This endpoint comparison explains why added restrictions can tighten bounds: they exclude some previously compatible values. Whether the resulting interval deserves greater substantive confidence depends on whether the restrictions are defensible. A transparent report distinguishes information coming from the observed distribution from narrowing that depends on maintained restrictions, rather than presenting a narrow interval without explaining its basis.

Worked Example: A Narrower Interval From an Added Restriction

Suppose a hypothetical data set and baseline assumptions imply an interval for an effect in risk-difference units of \([-0.12,0.28]\). Its width is \[ 0.28-(-0.12)=0.40, \] or 40 percentage points. It includes zero and effects of both signs.

An analyst then adds a substantive restriction and obtains \([0.04,0.10]\) from the same observed data. The new width is \[ 0.10-0.04=0.06, \] or 6 percentage points. Every effect in this second interval is positive, whereas the baseline interval did not settle the sign.

The second interval is more decisive, but the comparison does not show that the data alone established a positive effect. The added restriction removed zero and negative values from consideration. A careful interpretation reports both results and explains that the positive conclusion depends on the added restriction. It would be incorrect to describe the 6-percentage-point width as purely data-driven precision.

Diagnostics, Alternatives, and Limitations

A practical diagnostic is to ask three questions separately: how wide is the interval in meaningful units, what values does it include relative to zero or a decision threshold, and which features of the data and assumptions produce that width and location? Keeping these questions separate prevents a compact interval from being mistaken for a substantively decisive one, or an assumption-driven result from being mistaken for a data-driven result.

  • Check the scale. State \(U-L\) in the effect’s units and compare it with a meaningful range or decision margin. A numerical width without context is hard to interpret.
  • Check endpoints, not just the midpoint. The midpoint can lie on one side of a threshold even when the interval includes values on the other side. It does not summarize the uncertainty represented by the bounds.
  • Check the question’s boundary convention. “At least \(c\)” and “greater than \(c\)” differ at equality. State which criterion is being assessed.
  • Check estimation uncertainty. An estimated interval’s endpoints are themselves estimated. Do not treat them as known population endpoints when sampling uncertainty could change whether an endpoint is above, below, or equal to a threshold. Use the appropriate confidence-set methods from the earlier material on confidence sets for partially identified effects and bootstrap diagnostics for estimated bounds.
  • Check what narrowed the interval. Compare results under clearly described assumption sets when possible. Narrowness that appears only after an added restriction should be attributed to that restriction.

A point estimate can be easier to act on, but it selects one value rather than representing all effects compatible with partial identification. A conventional confidence interval for a point-identified parameter addresses sampling uncertainty about that parameter; it is not a substitute for an identified interval when the parameter is only partially identified. Sensitivity curves, discussed in the earlier material on sensitivity curves for treatment effect bounds, show how bounds change as a sensitivity parameter varies. They can help reveal what drives width, but do not by themselves turn an assumption-dependent result into a data-only conclusion.

Bounds have limits. An interval may be too wide to guide a particular decision even though it is mathematically valid and informative about the range of compatible effects. Conversely, a narrow interval may be conditional on strong assumptions. And if the reported endpoints are estimated, apparent separation from zero or a threshold may not persist once sampling uncertainty is accounted for. The right conclusion is therefore specific: state what the interval does establish, what it leaves unresolved, and what assumptions that conclusion depends on.

Common Mistake

A common mistake is to call an interval informative because its midpoint is above zero, or because its width looks small in isolation. For example, an interval \([-0.01,0.05]\) has midpoint \(0.02\), but it includes zero and negative values; its midpoint does not establish a positive effect. Another mistake is to call a threshold met whenever the upper endpoint reaches the threshold. For a rule requiring at least \(c\), \(U=c\) means the endpoint meets the rule, but lower values in the interval do not. The correction is to compare both endpoints with the specific boundary and state whether the criterion includes equality.

Key takeaway: Judge informativeness relative to a question, a meaningful scale, and the assumptions that generated the bounds. Width describes spread; endpoint location determines what can be concluded about sign or thresholds; neither should be interpreted without the other.

Check Your Understanding

Answer each question, then compare with the solutions below.

  1. An identified interval for an effect is \([-0.02,0.01]\). Does it establish a strictly positive effect? What is its width?
  2. A benefit criterion is “at least 4 units,” and the interval is \([1,4]\). Does every compatible effect meet the criterion? Does any compatible effect meet it?
  3. A criterion requires an effect strictly greater than 4 units, and the interval is \([2,4]\). What can be concluded?
  4. The same data yield \([-0.10,0.20]\) under baseline assumptions and \([0.03,0.08]\) after an additional restriction. What changed, and what should be said about the source of the narrower interval?

Solutions. (1) No. Zero lies in the interval, so the sign is not established. Its width is \(0.01-(-0.02)=0.03\) effect units. (2) No, not every compatible effect meets the criterion, because values below 4 are included. Yes, at least one does: the endpoint 4 meets an “at least 4” rule. (3) No compatible effect is strictly greater than 4, because the upper endpoint equals 4. (4) The added restriction narrowed the interval and excluded zero and negative values. The positive conclusion is conditional on that restriction; the narrower result should not be attributed to the observed data alone.

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