Trials that use: Interim analysis / alpha spending
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11,819 results
- Safety Study of Intravenous Ertapenem in Combination With Zidebactam (WCK 6777): Complete Statistical AnalysisIndependent statistical analysis of Safety Study of Intravenous Ertapenem in Combination With Zidebactam (WCK 6777): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Safety Study of IV Peramivir in Hospitalized Subjects With Confirmed or Suspected Influenza: Complete Statistical AnalysisIndependent statistical analysis of Safety Study of IV Peramivir in Hospitalized Subjects With Confirmed or Suspected Influenza: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Safety Study of KPT-330 (Selinexor) in Patients With Advanced or Metastatic Solid Tumor Cancer: Complete Statistical AnalysisIndependent statistical analysis of Safety Study of KPT-330 (Selinexor) in Patients With Advanced or Metastatic Solid Tumor Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Safety Study of MK-8237 Treatment in House-Dust-Mite Allergic Adolescents (MK-8237-008): Complete Statistical AnalysisIndependent statistical analysis of Safety Study of MK-8237 Treatment in House-Dust-Mite Allergic Adolescents (MK-8237-008): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01678807).
- Safety Study of Oral Edaravone Administered in Subjects With ALS: Complete Statistical AnalysisIndependent statistical analysis of Safety Study of Oral Edaravone Administered in Subjects With ALS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04165824).
- Safety Study of Oral Pirfenidone in Patients With Pulmonary Fibrosis/Idiopathic Pulmonary Fibrosis: Complete Statistical AnalysisIndependent statistical analysis of Safety Study of Oral Pirfenidone in Patients With Pulmonary Fibrosis/Idiopathic Pulmonary Fibrosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Safety Study of RMJH-111b to Treat Essential Hypertension: Complete Statistical AnalysisIndependent statistical analysis of Safety Study of RMJH-111b to Treat Essential Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02822222).
- Safety Study of Subcutaneously-Injected Prandial INSULIN-PH20 NP Compared to Insulin Lispro Injection in Participants With Type 1 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of Safety Study of Subcutaneously-Injected Prandial INSULIN-PH20 NP Compared to Insulin Lispro Injection in Participants With Type 1 Diabetes Mellitus: primary endpoint results, effect estimate with confidence interval, sample-size…
- Safety Study of Tezepelumab (AMG 157) in Healthy Adults and Adults With Atopic Dermatitis: Complete Statistical AnalysisIndependent statistical analysis of Safety Study of Tezepelumab (AMG 157) in Healthy Adults and Adults With Atopic Dermatitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Safety Study of the Effects of Inhaled Fluticasone Furoate/GW642444 on the Hypothalamic-Pituitary-Adrenal (HPA) Axis: Complete Statistical AnalysisIndependent statistical analysis of Safety Study of the Effects of Inhaled Fluticasone Furoate/GW642444 on the Hypothalamic-Pituitary-Adrenal (HPA) Axis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Safety Study of the Proteasome Inhibitor PR-171 (Carfilzomib for Injection) in Patients With Hematological Malignancies: Complete Statistical AnalysisIndependent statistical analysis of Safety Study of the Proteasome Inhibitor PR-171 (Carfilzomib for Injection) in Patients With Hematological Malignancies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Safety Study of XP12B in Women With Menorrhagia: Complete Statistical AnalysisIndependent statistical analysis of Safety Study of XP12B in Women With Menorrhagia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00113568).
- Safety Study That Compares Perlane to Perlane With Lidocaine (Perlane-L) While Correcting Wrinkles in the Area Around Your Nose: Complete Statistical AnalysisIndependent statistical analysis of Safety Study That Compares Perlane to Perlane With Lidocaine (Perlane-L) While Correcting Wrinkles in the Area Around Your Nose: primary endpoint results, effect estimate with confidence interval, sample-size…
- Safety, Dose Tolerance, Pharmacokinetics, Pharmacodynamics of CPX-POM in Patients With Newly Diagnosed or Recurrent Bladder Tumors: Complete Statistical AnalysisIndependent statistical analysis of Safety, Dose Tolerance, Pharmacokinetics, Pharmacodynamics of CPX-POM in Patients With Newly Diagnosed or Recurrent Bladder Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Safety, Efficacy and Pharmacokinetics of Rifaximin in Patients With Moderate-to-severe Papulopustular Rosacea: Complete Statistical AnalysisIndependent statistical analysis of Safety, Efficacy and Pharmacokinetics of Rifaximin in Patients With Moderate-to-severe Papulopustular Rosacea: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Safety, Efficacy and Tolerability of Vilazodone in (GAD) Generalized Anxiety Disorder: Complete Statistical AnalysisIndependent statistical analysis of Safety, Efficacy and Tolerability of Vilazodone in (GAD) Generalized Anxiety Disorder: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Safety, Efficacy and Tolerability Study of Paliperidone Extended-Release (ER) in Participants With Schizophrenia: Complete Statistical AnalysisIndependent statistical analysis of Safety, Efficacy and Tolerability Study of Paliperidone Extended-Release (ER) in Participants With Schizophrenia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Safety, Efficacy, and Pharmacokinetic Behavior of Leuprolide Mesylate (LMIS 25 mg) in Subjects With Prostate Cancer: Complete Statistical AnalysisIndependent statistical analysis of Safety, Efficacy, and Pharmacokinetic Behavior of Leuprolide Mesylate (LMIS 25 mg) in Subjects With Prostate Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Safety, Efficacy, and Pharmacokinetics of SKY0402 Administered as a Nerve Block in Subjects Undergoing Bunionectomy: Complete Statistical AnalysisIndependent statistical analysis of Safety, Efficacy, and Pharmacokinetics of SKY0402 Administered as a Nerve Block in Subjects Undergoing Bunionectomy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Safety, Efficacy, and Treatment Satisfaction Switching From Flolan to Remodulin Using the Crono Five Ambulatory Pump in Patients With PAH: Complete Statistical AnalysisIndependent statistical analysis of Safety, Efficacy, and Treatment Satisfaction Switching From Flolan to Remodulin Using the Crono Five Ambulatory Pump in Patients With PAH: primary endpoint results, effect estimate with confidence interval,…
- Safety, Efficacy, Longitudinal Costs and Patient-Centered Outcomes Using a TAAA Debranching Device: Complete Statistical AnalysisIndependent statistical analysis of Safety, Efficacy, Longitudinal Costs and Patient-Centered Outcomes Using a TAAA Debranching Device: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Safety, Immunogenicity and Compatibility With DTP of a Typhoid Fever Vaccine in Infants: Complete Statistical AnalysisIndependent statistical analysis of Safety, Immunogenicity and Compatibility With DTP of a Typhoid Fever Vaccine in Infants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Safety, Immunogenicity of RTS,S/AS02A, and RTS,S/AS01B Malaria Vaccines in Malaria-experienced Adults.: Complete Statistical AnalysisIndependent statistical analysis of Safety, Immunogenicity of RTS,S/AS02A, and RTS,S/AS01B Malaria Vaccines in Malaria-experienced Adults.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Safety, Immunogenicity, and Relative Efficacy of H1N1 Vaccines in Adults Aged 18 Years and Older: Complete Statistical AnalysisIndependent statistical analysis of Safety, Immunogenicity, and Relative Efficacy of H1N1 Vaccines in Adults Aged 18 Years and Older: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Safety, Pharmacokinetics and Efficacy of an ATIII Concentrate: Complete Statistical AnalysisIndependent statistical analysis of Safety, Pharmacokinetics and Efficacy of an ATIII Concentrate: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00319228).
- Safety, Pharmacokinetics and Efficacy Study of QCC374 in PAH Patients: Complete Statistical AnalysisIndependent statistical analysis of Safety, Pharmacokinetics and Efficacy Study of QCC374 in PAH Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02927366).
- Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411: Complete Statistical AnalysisIndependent statistical analysis of Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04101357).
- Safety, Pharmacokinetics,and Antiviral Activity of RV299 Against Respiratory Syncytical Virus (RSV): Complete Statistical AnalysisIndependent statistical analysis of Safety, Pharmacokinetics,and Antiviral Activity of RV299 Against Respiratory Syncytical Virus (RSV): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Safety, PK and Effectiveness of IV Peramivir Versus Oseltamivir in Pediatric Subjects With Uncomplicated Influenza: Complete Statistical AnalysisIndependent statistical analysis of Safety, PK and Effectiveness of IV Peramivir Versus Oseltamivir in Pediatric Subjects With Uncomplicated Influenza: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Safety, Tolerability and Drug- Drug Interaction Study of Ubrogepant With Erenumab or Galcanezumab in Participants With Migraine: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Drug- Drug Interaction Study of Ubrogepant With Erenumab or Galcanezumab in Participants With Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Safety, Tolerability and Efficacy of SPD503 in Treating ADHD in Children Aged 6-17: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Efficacy of SPD503 in Treating ADHD in Children Aged 6-17: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Safety, Tolerability and Efficacy Study of STX209 in Subjects With Fragile X Syndrome: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Efficacy Study of STX209 in Subjects With Fragile X Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Safety, Tolerability and Immunogenicity of HPV (Human Papilloma Virus) Vaccine in Healthy Females 9 to 15 Years of Age in India (V501-029): Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Immunogenicity of HPV (Human Papilloma Virus) Vaccine in Healthy Females 9 to 15 Years of Age in India (V501-029): primary endpoint results, effect estimate with…
- Safety, Tolerability and Immunogenicity of Three Doses of Novartis Meningococcal B Vaccine When Administered to Healthy At-risk Adults: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Immunogenicity of Three Doses of Novartis Meningococcal B Vaccine When Administered to Healthy At-risk Adults: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Safety, Tolerability and Immunogenicity of V114 in Healthy Adults and Infants (V114-004): Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Immunogenicity of V114 in Healthy Adults and Infants (V114-004): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Safety, Tolerability and Long-term Immunogenicity of Different Formulations of a Chikungunya Vaccine (V184-005): Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Long-term Immunogenicity of Different Formulations of a Chikungunya Vaccine (V184-005): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Safety, Tolerability and Pharmacokinetic Investigation of GSK3882347 in Healthy Participants.: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Pharmacokinetic Investigation of GSK3882347 in Healthy Participants.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04488770).
- Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Locally Advanced or Metastatic Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Locally Advanced or Metastatic Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size…
- Safety, Tolerability and Pharmacokinetics of Different Multiple Doses of BI 207127 BID and Multiple Doses of BI 207127 Combined With Faldaprevir in Healthy Male and Female Subjects: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Pharmacokinetics of Different Multiple Doses of BI 207127 BID and Multiple Doses of BI 207127 Combined With Faldaprevir in Healthy Male and Female Subjects: primary…
- Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of BI 691751 in Healthy Asian Male Volunteers: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of BI 691751 in Healthy Asian Male Volunteers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Safety, Tolerability and Pharmacokinetics Study of MK-7252 in Healthy Adult Participants (MK-7252-001): Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Pharmacokinetics Study of MK-7252 in Healthy Adult Participants (MK-7252-001): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Safety, Tolerability and PK of Intravenous (IV) ETI-204 Alone and in Presence of Ciprofloxacin in Adult Volunteers: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and PK of Intravenous (IV) ETI-204 Alone and in Presence of Ciprofloxacin in Adult Volunteers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Safety, Tolerability and PK of Multiple-ascending Doses of Emodepside: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and PK of Multiple-ascending Doses of Emodepside: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03383614).
- Safety, Tolerability and Preliminary Pharmacokinetics (PK) and Pharmacodynamics (PD) of Single and Repeat Oral Doses of GSK3008356 in Healthy and Obese Subjects: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Preliminary Pharmacokinetics (PK) and Pharmacodynamics (PD) of Single and Repeat Oral Doses of GSK3008356 in Healthy and Obese Subjects: primary endpoint results, effect estimate with…
- Safety, Tolerability and Prophylactic Antiviral Activity of Neumifil Against Influenza Via a Human Viral Challenge Model: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability and Prophylactic Antiviral Activity of Neumifil Against Influenza Via a Human Viral Challenge Model: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19: Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19: primary endpoint results, effect estimate with confidence…
- Safety, Tolerability, and Efficacy of Monotherapy and Combination Regimens in Participants With Nonalcoholic Steatohepatitis (NASH): Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability, and Efficacy of Monotherapy and Combination Regimens in Participants With Nonalcoholic Steatohepatitis (NASH): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Safety, Tolerability, and Efficacy Study of rAvPAL-PEG Administered Daily in Subjects With Phenylketonuria (PKU): Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability, and Efficacy Study of rAvPAL-PEG Administered Daily in Subjects With Phenylketonuria (PKU): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Safety, Tolerability, and Immunogenicity of a Single Dose of Merck 0657nI Staphylococcus Aureus Vaccine With or Without Merck Aluminum Adjuvant (V710-002): Complete Statistical AnalysisIndependent statistical analysis of Safety, Tolerability, and Immunogenicity of a Single Dose of Merck 0657nI Staphylococcus Aureus Vaccine With or Without Merck Aluminum Adjuvant (V710-002): primary endpoint results, effect estimate with confidence…